STRUCTURE, AND UREASE INHIBITORY ACTIVITY OF COPPER(II) COMPLEX WITH (E)-3-(2,3-DIHYDROBENZO[B][1,4]DIOXIN-6-YL)ACRYLIC ACID

2017 ◽  
Keyword(s):  
Acrylic Acid ◽  
Inhibitory Activity ◽  
Urease Inhibitory

Structure and urease inhibitory activity of copper(II) complex with (E)-3-(2,3-dihydrobenzo[b][1,4]dioxin-6-yl)acrylic acid

2017 ◽  
Vol 58 (4) ◽  
pp. 797-803 ◽  
Author(s):  
X.-F. Chen ◽  
C.-F. Wang ◽  
S. Kong ◽  
C. Li ◽  
X. Zhou ◽  
...  
Keyword(s):  
Acrylic Acid ◽  
Inhibitory Activity ◽  
Urease Inhibitory

Synthesis and Urease Inhibitory Activity of Some 5-Aminomethylene Barbituric/Thiobarbituric Acid Derivatives

2018 ◽  
Vol 15 (4) ◽  
pp. 428-436 ◽  
Author(s):  
Mehdi Asadi ◽  
Mohammad Mahdavi ◽  
Shabnam Mahernia ◽  
Zahra Rezaei ◽  
Maliheh Safavi ◽  
...  
Keyword(s):  
Inhibitory Activity ◽  
Thiobarbituric Acid ◽  
Urease Inhibitory

THEVETIA PERUVIANA ROOTS EXTRACT MEDICATED GOLD NANOPARTICLES AND ITS UREASE INHIBITORY ACTIVITY

2021 ◽  
pp. 79-82
Author(s):  
SAUD BAWAZEER
Keyword(s):  
Gold Nanoparticles ◽  
Aqueous Extract ◽  
Inhibitory Activity ◽  
Enzyme Inhibitor ◽  
Research Work ◽  
Thevetia Peruviana ◽  
Urease Enzyme ◽  
Urease Inhibitory ◽  
Microscopy Techniques

Objective: The main objective of the current research work was synthesized of gold nanoparticles (AuNPs) of Thevetia peruviana aqueous extract,characterization, and screening for urease enzyme inhibitory activity.Methods: AuNPs were synthesized by mixing 1 mM gold salt solution with T. peruviana aqueous extract without any reducing agents. The preparedAuNPs were characterized using UV–visible spectroscopy, Fourier transform infrared spectroscopy, and scanning electron microscopy techniques. Thesynthesized AuNPs were assessed for in vitro urease enzyme inhibitory activity at 0.2 μg in comparison with the aqueous extract.Results: In this finding, we synthesized the AuNPs of T. peruviana aqueous extract for the 1st time. The AuNPs exhibited significant stability atroom temperature. The AuNPs showed significant urease inhibitory activity with IC50 67.56±1.67 at 0.2 μg as compared to aqueous extract whichexhibited good activity with IC50 39.21±1.32 μ at 0.2 mg, against standard thiourea (IC50=21.00±1.16). The formation of AuNPs correlates due to activephytochemical present in extract which is responsible for synthesizing NPs.Conclusion: T. peruviana extract and prepared AuNPs are an outstanding urease enzyme inhibitor and are capable of making fine NPs. Application:The synthesized AuNPs of T. peruviana aqueous extract which significant urease inhibitory activity may allow us to discover NPs for potentiallyeffective and safe nanoherbal therapy.

Urease inhibitory activity of simple α,β-unsaturated ketones

Life Sciences ◽  
2003 ◽  
Vol 73 (23) ◽  
pp. 2985-2990 ◽  
Author(s):  
Toru Tanaka ◽  
Masami Kawase ◽  
Satoru Tani
Keyword(s):  
Inhibitory Activity ◽  
Unsaturated Ketones ◽  
Urease Inhibitory
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