CRYSTAL STRUCTURES OF TETRAKIS(HYDROXYACETATO)bis(DIMETHYL-SULFOXIDE)DIRHODIUM(II)

2017 ◽  
Keyword(s):  
Dimethyl Sulfoxide ◽  
Crystal Structures

Synthesis and crystal structures of some bis(3-methyl-1H-indol-2-yl)(salicyl)methanes

2019 ◽  
Vol 75 (1) ◽  
pp. 65-69
Author(s):  
Wyatt Cole ◽  
Stephanie L. Hemmingson ◽  
Audrey C. Eisenberg ◽  
Catherine A. Ulman ◽  
Joseph M. Tanski ◽  
...  
Keyword(s):  
Hydrogen Bonding ◽  
Dimethyl Sulfoxide ◽  
Crystal Structures ◽  
Double Layer ◽  
Acid Catalysis ◽  
Double Layers ◽  
One Dimensional ◽  
Salicylaldehyde Derivatives ◽  
Central Carbon ◽  
Solvent Molecules

Four 2,2′-bisindolylmethanes (BIMs), a useful class of polyindolyl species joined to a central carbon, were synthesized using salicylaldehyde derivatives and simple acid catalysis; these are 2-[bis(3-methyl-1H-indol-2-yl)methyl]-6-methylphenol, (IIa), 2-[bis(3-methyl-1H-indol-2-yl)methyl]-4,6-dichlorophenol, (IIb), 2-[bis(3-methyl-1H-indol-2-yl)methyl]-4-nitrophenol, (IIc), and 2-[bis(3-methyl-1H-indol-2-yl)methyl]-4,6-di-tert-butylphenol, (IId). BIMs (IIa) and (IIb) were characterized crystallographically as the dimethyl sulfoxide (DMSO) disolvates, i.e. C26H24N2O·2C2H6OS and C25H20Cl2N2O·2C2H6OS, respectively. Both form strikingly similar one-dimensional hydrogen-bonding chain motifs with the DMSO solvent molecules. BIM (IIa) packs into double layers of chains whose orientations alternate every double layer, while (IIb) forms more simply packed chains along the a axis. BIM (IIa) has a remarkably long c axis.

N—H...S and N—H...O hydrogen bonds: `pure' and `mixed'R22(8) patterns in the crystal structures of eight 2-thiouracil derivatives

2014 ◽  
Vol 70 (2) ◽  
pp. 241-249 ◽  
Author(s):  
Wilhelm Maximilian Hützler ◽  
Ernst Egert
Keyword(s):  
Hydrogen Bond ◽  
Hydrogen Bonding ◽  
Hydrogen Bonds ◽  
Dimethyl Sulfoxide ◽  
Crystal Structures ◽  
Thiouracil Derivatives ◽  
Bonding Patterns

The preferred hydrogen-bonding patterns in the crystal structures of 5-propyl-2-thiouracil, C7H10N2OS, (I), 5-methoxy-2-thiouracil, C5H6N2O2S, (II), 5-methoxy-2-thiouracil–N,N-dimethylacetamide (1/1), C5H6N2O2S·C4H9NO, (IIa), 5,6-dimethyl-2-thiouracil, C6H8N2OS, (III), 5,6-dimethyl-2-thiouracil–1-methylpyrrolidin-2-one (1/1), C6H8N2OS·C5H9NO, (IIIa), 5,6-dimethyl-2-thiouracil–N,N-dimethylformamide (2/1), 2C6H8N2OS·C3H7NO, (IIIb), 5,6-dimethyl-2-thiouracil–N,N-dimethylacetamide (2/1), 2C6H8N2OS·C4H9NO, (IIIc), and 5,6-dimethyl-2-thiouracil–dimethyl sulfoxide (2/1), 2C6H8N2OS·C2H6OS, (IIId), were analysed. All eight structures containR22(8) patterns. In (II), (IIa), (III) and (IIIa), they are formed by two N—H...S hydrogen bonds, and in (I) by alternating pairs of N—H...S and N—H...O hydrogen bonds. In contrast, the structures of (IIIb), (IIIc) and (IIId) contain `mixed'R22(8) patterns with one N—H...S and one N—H...O hydrogen bond, as well asR22(8) motifs with two N—H...O hydrogen bonds.

scholarly journals Four cytotoxic N4-substituted thiosemicarbazones derived from 2-hydroxynaphthalene-1-carboxaldehyde

2003 ◽  
Vol 59 (11) ◽  
pp. o629-o633 ◽  
Author(s):  
Paul V. Bernhardt ◽  
Lorraine M. Caldwell ◽  
David B. Lovejoy ◽  
Des R. Richardson
Keyword(s):  
Dimethyl Sulfoxide ◽  
Crystal Structures ◽  
Metal Ion ◽  
Antitumour Activity ◽  
Donor Ligands ◽  
Ion Binding ◽  
Metal Ion Binding ◽  
X Ray ◽  
Conformational Variations ◽  
Optimum Conformation

The X-ray crystal structures are reported of four novel and potentially O,N,S-tridentate donor ligands that demonstrate antitumour activity. These ligands are 1-[(4-methylthiosemicarbazono)methyl]-2-naphthol, C13H13N3OS, (III), 1-[(4-ethylthiosemicarbazono)methyl]-2-naphthol, C14H15N3OS, (IV), 1-[(4-phenylthiosemicarbazono)methyl]-2-naphthol, C18H15N3OS, (V), and 1-[(4,4-dimethylthiosemicarbazono)methyl]-2-naphthol dimethyl sulfoxide solvate, C14H15N3OS·C2H6OS, (VI). These chelators are N4-substituted thiosemicarbazones, each based on the same parent aldehyde, namely 2-zhydroxynaphthalene-1-carboxaldehyde isonicotinoylhydrazone. Conformational variations within this series are discussed in relation to the optimum conformation for metal-ion binding.

Crystal Structures of the Amide and Iminol Tautomers O-(3,5-dinitrobenzoyloxy)benzohydroxamate. A Case of a Disappearing Solvate?

2016 ◽  
Vol 69 (10) ◽  
pp. 1193 ◽  
Author(s):  
Abigail L. Albright ◽  
Lucy Collins ◽  
John Li ◽  
Benjamin Harris ◽  
Jonathan M. White
Keyword(s):  
Dimethyl Sulfoxide ◽  
Crystal Structures ◽  
Infrared Spectra ◽  
Tautomeric Form ◽  
Spectral Characteristics ◽  
Benzohydroxamic Acid ◽  
Hydrogen Bonded

The O-(3,5-dinitrobenzoyl) derivative of benzohydroxamic acid 1 crystallizes in its iminol tautomeric form, hydrogen bonded to a molecule of dimethyl sulfoxide (DMSO) when crystallized from methanol in the presence of DMSO. In contrast, in the absence of DMSO, 1 crystallizes in its amide tautomeric form. Computations suggest that in the absence of DMSO, the amide tautomer of 1 is significantly more stable than the iminol form. Conversely, in the presence of DMSO, the two forms have comparable stabilities. Solution infrared spectra of 1 run in dichloromethane are consistent with the amide tautomeric form predominating; however, titration of aliquots of DMSO results in the formation of a second species with spectral characteristics consistent with the iminol tautomer.

Cobalt(II) complex with 4,4,4-trifluoro-1-thienylbutane-1,3-dione and dimethyl sulfoxide: Molecular and crystal structures

2011 ◽  
Vol 37 (6) ◽  
pp. 428-430 ◽  
Author(s):  
A. M. Magerramov ◽  
R. A. Alieva ◽  
A. V. Kurbanov ◽  
F. N. Bakhmanova ◽  
F. M. Chyragov
Keyword(s):  
Dimethyl Sulfoxide ◽  
Crystal Structures ◽  
Molecular And Crystal Structures
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