The subject of this research is the examination of focal areas of providing medical aid to children of Western Siberia during the Great Patriotic War. Leaning on the previously unpublished documents, the author analyzes the data on the adoption of measures for rendering medical and sanitary services to evacuated children, as well as development of the network of specialized childcare facilities under the jurisdiction of the People's Commissariat for Health: nurseries, orphanages, children's hospitals and polyclinics, consultations, maternity hospitals, etc. The article provides materials on the changes in staffing in the indicated medical facilities, and measures on improvement of qualifications of medical personnel. The author examines the nature of changes in the quality of medical care for children that was aimed at reduction of morbidity and mortality rates. The conclusion is formulated that in Western Siberia healthcare services for children, which faced a number of problems in the prewar period, failed to prepare for multifold increase of strain with the beginning of the Great Patriotic War. Shortage of resources led to degradation of the quality of medical services provided to children, which resulted in the increased morbidity and mortality among them. However, public health authorities undertook methodical efforts towards strengthening children's healthcare system, which in the 1943-1945 turned the tide in children mortality.