scholarly journals Prognostic Value of Heart Rate Profiles During Cardiopulmonary Exercise Testing in Patients With Cardiac Disease

2009 ◽  
Vol 50 (1) ◽  
pp. 59-71 ◽  
Author(s):  
Ayumi Goda ◽  
Akira Koike ◽  
Masayo Hoshimoto- Iwamoto ◽  
Osamu Nagayama ◽  
Kaori Yamaguchi ◽  
...  
Keyword(s):  
Heart Rate ◽  
Exercise Testing ◽  
Cardiac Disease ◽  
Prognostic Value ◽  
Cardiopulmonary Exercise Testing ◽  
Cardiopulmonary Exercise

scholarly journals Impairments in Blood Pressure Regulation and Cardiac Baroreceptor Sensitivity Among Patients With Heart Failure Supported With Continuous-Flow Left Ventricular Assist Devices

2021 ◽  
Vol 14 (1) ◽  
Author(s):  
Christine Sailer ◽  
Hannah Edelmann ◽  
Cullen Buchanan ◽  
Pedro Giro ◽  
Matthew Babcock ◽  
...  
Keyword(s):  
Heart Failure ◽  
Heart Rate ◽  
Exercise Testing ◽  
Cardiopulmonary Exercise Testing ◽  
Left Ventricular ◽  
Advanced Heart Failure ◽  
Ventricular Assist Devices ◽  
Left Ventricular Assist Devices ◽  
Baroreceptor Sensitivity ◽  
Cardiopulmonary Exercise

Background: Continuous-flow (CF) left ventricular assist devices (LVADs) improve outcomes for patients with advanced heart failure (HF). However, the lack of a physiological pulse predisposes to side-effects including uncontrolled blood pressure (BP), and there are little data regarding the impact of CF-LVADs on BP regulation. Methods: Twelve patients (10 males, 60±11 years) with advanced heart failure completed hemodynamic assessment 2.7±4.1 months before, and 4.3±1.3 months following CF-LVAD implantation. Heart rate and systolic BP via arterial catheterization were monitored during Valsalva maneuver, spontaneous breathing, and a 0.05 Hz repetitive squat-stand maneuver to characterize cardiac baroreceptor sensitivity. Plasma norepinephrine levels were assessed during head-up tilt at supine, 30 o and 60 o . Heart rate and BP were monitored during cardiopulmonary exercise testing. Results: Cardiac baroreceptor sensitivity, determined by Valsalva as well as Fourier transformation and transfer function gain of Heart rate and systolic BP during spontaneous breathing and squat-stand maneuver, was impaired before and following LVAD implantation. Norepinephrine levels were markedly elevated pre-LVAD and improved—but remained elevated post-LVAD (supine norepinephrine pre-LVAD versus post-LVAD: 654±437 versus 323±164 pg/mL). BP increased during cardiopulmonary exercise testing post-LVAD, but the magnitude of change was modest and comparable to the changes observed during the pre-LVAD cardiopulmonary exercise testing. Conclusions: Among patients with advanced heart failure with reduced ejection fraction, CF-LVAD implantation is associated with modest improvements in autonomic tone, but persistent reductions in cardiac baroreceptor sensitivity. Exercise-induced increases in BP are blunted. These findings shed new light on mechanisms for adverse events such as stroke, and persistent reductions in functional capacity, among patients supported by CF-LVADs. Registration: URL: https://www.clinicaltrials.gov ; Unique identifier: NCT03078972.

Prognostic value of cardiopulmonary exercise testing in Idiopathic Dilated Cardiomyopathy

2016 ◽  
Vol 223 ◽  
pp. 596-603 ◽  
Author(s):  
Gianfranco Sinagra ◽  
Annamaria Iorio ◽  
Marco Merlo ◽  
Antonio Cannatà ◽  
Davide Stolfo ◽  
...  
Keyword(s):  
Dilated Cardiomyopathy ◽  
Exercise Testing ◽  
Prognostic Value ◽  
Cardiopulmonary Exercise Testing ◽  
Idiopathic Dilated Cardiomyopathy ◽  
Cardiopulmonary Exercise

Mo1045 Prognostic Value of Cardiopulmonary Exercise Testing (CPX) in Upper Gastrointestinal (UGI) Cancer Management

2012 ◽  
Vol 142 (5) ◽  
pp. S-580
Author(s):  
Andrew J. Beamish ◽  
David S. Chan ◽  
Tom D. Reid ◽  
Nicola C. Tanner ◽  
Ian Appadurai ◽  
...  
Keyword(s):  
Exercise Testing ◽  
Prognostic Value ◽  
Cardiopulmonary Exercise Testing ◽  
Cancer Management ◽  
Cardiopulmonary Exercise ◽  
Upper Gastrointestinal
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