scholarly journals Increased Lipoprotein (a) and Its Relationships with Other Parameters of Lipoprotein Metabolism in Chronic Renal Failure Treated by Hemodialysis.

1997 ◽  
Vol 38 (1) ◽  
pp. 83-89 ◽  
Author(s):  
M. Ramazan YIGITOGLU ◽  
M. Fevzi POLAT ◽  
Fatih AKÇAY ◽  
Zeki ARI ◽  
B. Sami UYANIK ◽  
...  
Keyword(s):  
Renal Failure ◽  
Chronic Renal Failure ◽  
Lipoprotein Metabolism ◽  
Lipoprotein A

Dyslipidemia of chronic renal failure: the nature, mechanisms, and potential consequences

2006 ◽  
Vol 290 (2) ◽  
pp. F262-F272 ◽  
Author(s):  
N. D. Vaziri
Keyword(s):  
Renal Failure ◽  
Chronic Renal Failure ◽  
Hepatic Lipase ◽  
Low Density Lipoprotein ◽  
Plasma Concentrations ◽  
Cholesterol Acyltransferase ◽  
Lipoprotein Metabolism ◽  
Density Lipoprotein ◽  
Triglyceride Rich Lipoprotein ◽  
Density Lipoprotein Receptor

Chronic renal failure (CRF) results in profound lipid disorders, which stem largely from dysregulation of high-density lipoprotein (HDL) and triglyceride-rich lipoprotein metabolism. Specifically, maturation of HDL is impaired and its composition is altered in CRF. In addition, clearance of triglyceride-rich lipoproteins and their atherogenic remnants is impaired, their composition is altered, and their plasma concentrations are elevated in CRF. Impaired maturation of HDL in CRF is primarily due to downregulation of lecithin-cholesterol acyltransferase (LCAT) and, to a lesser extent, increased plasma cholesteryl ester transfer protein (CETP). Triglyceride enrichment of HDL in CRF is primarily due to hepatic lipase deficiency and elevated CETP activity. The CRF-induced hypertriglyceridemia, abnormal composition, and impaired clearance of triglyceride-rich lipoproteins and their remnants are primarily due to downregulation of lipoprotein lipase, hepatic lipase, and the very-low-density lipoprotein receptor, as well as, upregulation of hepatic acyl-CoA cholesterol acyltransferase (ACAT). In addition, impaired HDL metabolism contributes to the disturbances of triglyceride-rich lipoprotein metabolism. These abnormalities are compounded by downregulation of apolipoproteins apoA-I, apoA-II, and apoC-II in CRF. Together, these abnormalities may contribute to the risk of arteriosclerotic cardiovascular disease and may adversely affect progression of renal disease and energy metabolism in CRF.

Lipoprotein(a) in Diabetic Patients with and Without Chronic Renal Failure

Diabetes Care ◽  
1992 ◽  
Vol 15 (8) ◽  
pp. 976-979 ◽  
Author(s):  
P. J. Guillausseau ◽  
J. Peynet ◽  
P. Chanson ◽  
A. Legrand ◽  
J. J. Altman ◽  
...  
Keyword(s):  
Renal Failure ◽  
Chronic Renal Failure ◽  
Diabetic Patients ◽  
Lipoprotein A

scholarly journals Lipoprotein (a) in Chronic Renal Failure Patients Undergoing Hemodialysis: Does It Have an Independent Role in the Development of Further Cardiovascular Complications?

Nephron ◽  
1993 ◽  
Vol 65 (4) ◽  
pp. 644-645 ◽  
Author(s):  
Jorge del Cura ◽  
Antonio Gil-Paraiso ◽  
Luis Borque ◽  
Maria-Eugenia Carazo ◽  
Carlos Maside ◽  
...  
Keyword(s):  
Renal Failure ◽  
Chronic Renal Failure ◽  
Cardiovascular Complications ◽  
Lipoprotein A

scholarly journals Significance of lipoprotein(a) in diabetic chronic renal failure

2017 ◽  
Vol 5 (9) ◽  
pp. 3856
Author(s):  
Vasanthan M.
Keyword(s):  
Diabetes Mellitus ◽  
Metabolic Disease ◽  
Renal Failure ◽  
Chronic Renal Failure ◽  
The Other ◽  
Lipoprotein A ◽  
Positive Correlation ◽  
Duration Of Diabetes

Background: Diabetes mellitus, is a metabolic disease with an alarming prevalence worldwide. When uncontrolled, this can result in diseases such as chronic renal failure by various atherogenic factors including lipoprotein(a). Aim was to estimate the level of lipoprotein(a) in diabetic chronic renal failure patients and to correlate with healthy controls.Methods: 30 non-diabetic subjects and 30 diabetic CRF patients were included in the study. Lipoprotein(a) was estimated by immunoturbidimetric method and the other parameters by their respective methods in biochemistry auto-analyzer.Results: It was found from the study that there is a positive correlation of lipoprotein(a) levels with the duration of diabetes and was progressive with the diabetic complications.Conclusions: Lipoprotein(a) is responsible for atherogenic events in CRF patients.

scholarly journals Low-Molecular-Weight Heparin and Lipoprotein(a) in Patients with Chronic Renal Failure

Nephron ◽  
1997 ◽  
Vol 76 (1) ◽  
pp. 123-124 ◽  
Author(s):  
Andrea Sagripanti ◽  
Vincenzo Cozza ◽  
Giuliano Barsotti
Keyword(s):  
Molecular Weight ◽  
Renal Failure ◽  
Chronic Renal Failure ◽  
Low Molecular Weight Heparin ◽  
Low Molecular Weight ◽  
Lipoprotein A

Lipoprotein (a) in Chronic Renal Failure: Effect of Maintenance Hemodialysis

2003 ◽  
Vol 7 (4) ◽  
pp. 326-331 ◽  
Author(s):  
Om Prakash Kalra ◽  
Ambar Khaira ◽  
Jasvinder Kaur Gambhir ◽  
Sunil Agarwal ◽  
Satish Kumar Bhargava
Keyword(s):  
Renal Failure ◽  
Chronic Renal Failure ◽  
Maintenance Hemodialysis ◽  
Lipoprotein A

Plasma levels of lipoprotein (a) do not predict progression of human chronic renal failure

1996 ◽  
Vol 11 (11) ◽  
pp. 2237-2243 ◽  
Author(s):  
O. Samuelsson ◽  
P.-O. Attman ◽  
C. Knight-Gibson ◽  
R. Larsson ◽  
H. Mulec ◽  
...  
Keyword(s):  
Renal Failure ◽  
Chronic Renal Failure ◽  
Plasma Levels ◽  
Lipoprotein A

Lipoprotein (a) in the Interstitial Fluid and Serum of Patients with Chronic Renal Failure and Matched Controls

1996 ◽  
Vol 91 (s35) ◽  
pp. 11P-12P
Author(s):  
G.N.I. Wood ◽  
D. Bhatnagar ◽  
M.I. MacKness ◽  
W A Herd ◽  
C.D. Short ◽  
...  
Keyword(s):  
Renal Failure ◽  
Chronic Renal Failure ◽  
Interstitial Fluid ◽  
Lipoprotein A
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