scholarly journals Recovery of Iodine-123 Metaiodobenzylguanidine Uptake Associated with Left Ventricular Functional Recovery in a Patient with Dilated Cardiomyopathy. Endomyocardial Histological Findings before and after the Improvement of Uptake.

1997 ◽  
Vol 38 (1) ◽  
pp. 145-150 ◽  
Author(s):  
Toshiyuki UEDA ◽  
Shozo KUSACHI ◽  
Hirosuke YAMAJI ◽  
Naoya MORISHITA ◽  
Tsutomu MIMA ◽  
...  
Keyword(s):  
Dilated Cardiomyopathy ◽  
Functional Recovery ◽  
Left Ventricular ◽  
Histological Findings ◽  
Iodine 123 Metaiodobenzylguanidine ◽  
Before And After ◽  
Iodine 123

scholarly journals Survival and echocardiographic evaluation of dogs with idiopathic dilated cardiomyopathy treated with carvedilol

2010 ◽  
Vol 62 (3) ◽  
pp. 555-563 ◽  
Author(s):  
E.C. Soares ◽  
G.G. Pereira ◽  
L.C. Petrus ◽  
M. Leomil Neto ◽  
F.L. Yamaki ◽  
...  
Keyword(s):  
Dilated Cardiomyopathy ◽  
Ventricular Remodeling ◽  
Left Ventricular ◽  
Idiopathic Dilated Cardiomyopathy ◽  
P Value ◽  
Echocardiographic Evaluation ◽  
Before And After ◽  
Group A ◽  
The Stability ◽  
Group B

Sixty dogs with idiopathic dilated cardiomyopathy were randomly treated with traditional therapy - digitalis, diuretics, angiotensin-converting inhibitors - (group A) or treated with these drugs plus carvedilol (group B). Echocardiographic variables were measured before and after 3, 13, 26, and 52 weeks of treatment or until death. Comparisons between groups and time were performed. No significant differences between groups were found in the most of the echocardiographic variables. The left ventricular end-systolic diameter indexed to body surface area (LVESDi) increased significantly in the group A dogs compared to the group B animals. The survival of groups A and B dogs were not different (P-value=0.1137). In conclusion, the stability of the LVESDi observed in the group treated with carvedilol may represent the beneficial effect over the ventricular remodeling.

Use of Technetium-99m-Labeled Methoxy-Isobutyl Isonitrile and Iodine 123-Labeled Phenyl-Methyl-Pentadecanoic Acid in the Diagnosis and Prognosis of Patients with Dilated Cardiomyopathy

2015 ◽  
Vol 1084 ◽  
pp. 532-535
Author(s):  
Yuri B. Lishmanov ◽  
Konstantin V. Zavadovsky ◽  
Marina O. Gulya ◽  
Stanislav M. Minin ◽  
Denis I. Lebedev
Keyword(s):  
Dilated Cardiomyopathy ◽  
Left Ventricular ◽  
Cardiac Resynchronization ◽  
Pentadecanoic Acid ◽  
Resynchronization Therapy ◽  
Diagnosis And Prognosis ◽  
Metabolic Defects ◽  
Iodine 123 ◽  
Selection Of Patients ◽  
Selection Of

The objectiveof this study is to assess perfusion and metabolic state of the left ventricular in patients with dilated cardiomyopathy (DCM) using scintigraphy with MIBI and BMIPP, as well as to develop the predictors of efficacy of cardiac resynchronization therapy (CRT). The study included 51 patients with DCM who underwent CRT. Correlation between the values of LV ESV after CRT and preoperative perfusion and metabolic defects sizes was detected. "Responders" and "non-responders" groups were significantly different from the perfusion and metabolic defects sizes. Myocardial perfusion-metabolic scintigraphy can be used as additional criteria for the selection of patients for CRT.

scholarly journals Relation of iodine-123 metaiodobenzylguanidine myocardial scintigraphy to endomyocardial biopsy findings in patients with dilated cardiomyopathy

1997 ◽  
Vol 20 (1) ◽  
pp. 61-66 ◽  
Author(s):  
Katsutoshi Murata ◽  
Shozo Kusachi ◽  
Takashi Murakami ◽  
Kunio Nogami ◽  
Masahiro Murakami ◽  
...  
Keyword(s):  
Dilated Cardiomyopathy ◽  
Endomyocardial Biopsy ◽  
Myocardial Scintigraphy ◽  
Iodine 123 Metaiodobenzylguanidine ◽  
Iodine 123

Abstract 17860: Cardiac Iodine-123 Metaiodobenzylguanidine Imaging Predicts Poor Prognosis Even in Patients Admitted With Acute Decompensated Heart Failure

Circulation ◽  
2015 ◽  
Vol 132 (suppl_3) ◽  
Author(s):  
Shunsuke Tamaki ◽  
Takahisa Yamada ◽  
Takashi Morita ◽  
Yoshio Furukawa ◽  
Yusuke Iwasaki ◽  
...  
Keyword(s):  
Heart Failure ◽  
Acute Decompensated Heart Failure ◽  
Decompensated Heart Failure ◽  
Left Ventricular ◽  
Left Ventricular Ejection ◽  
Washout Rate ◽  
Mibg Imaging ◽  
Ventricular Ejection Fraction ◽  
Iodine 123 Metaiodobenzylguanidine ◽  
Iodine 123

Introduction: Cardiac iodine-123 metaiodobenzylguanidine (MIBG) imaging has been shown to provide prognostic information in patients with chronic heart failure. However, little is known about the prognostic value of cardiac MIBG imaging in patients admitted with acute decompensated heart failure (ADHF). Hypothesis: We assessed the hypothesis that cardiac MIBG imaging might also be useful for the prediction of poor clinical outcome in patients admitted with ADHF. Methods: We studied 115 consecutive patients admitted for ADHF from October 2011 to January 2013 and discharged with survival (age: 74±13 years, male: 56%, NYHA class at discharge: 2.2±0.8, left ventricular ejection fraction measured by echocardiography: 47.1±15.5%). Cardiac MIBG imaging, echocardiography and venous blood sampling were performed just before discharge. The cardiac MIBG heart-to-mediastinum ratio (H/M) and washout rate were calculated from the chest anterior view images obtained at 20 and 200min after isotope injection. The endpoints were unplanned hospitalization for worsening heart failure (WHF) and pump failure death (PFD). Results: During a follow-up period of 2.0±0.8 years, 32 patients had WHF and 15 patients had PFD. At multivariate Cox analysis, out of the variables including clinical, hemodynamic, biochemical, echocardiographic and MIBG parameters, H/M on delayed image (late H/M) was independently associated with WHF (p=0.0003) and PFD (p=0.0255), although brain natriuretic peptide showed the significant association with the endpoints at univariate analysis. Kaplan-Meier analysis showed that the patients with late H/M <1.65 (mean value) had a significantly higher risk of both WHF and PFD than those with late H/M ≧1.65 (Figure). Conclusions: Cardiac MIBG imaging could predict poor outcome even in patients admitted with ADHF.

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