Serum angiotensin converting enzyme (S-ACE) activity in patients with chronic renal failure on regular hemodialysis.

1984 ◽  
Vol 25 (1) ◽  
pp. 87-92 ◽  
Author(s):  
Hiroshi MIURA ◽  
Mahito NAKAYAMA ◽  
Tatsuo SATO
Keyword(s):  
Renal Failure ◽  
Chronic Renal Failure ◽  
Angiotensin Converting Enzyme ◽  
Converting Enzyme ◽  
Serum Angiotensin Converting Enzyme ◽  
Ace Activity ◽  
Regular Hemodialysis

Serum angiotensin-converting enzyme in healthy and sarcoidotic children: comparison with the reference interval for adults

1990 ◽  
Vol 36 (2) ◽  
pp. 344-346 ◽  
Author(s):  
B Bénéteau-Burnat ◽  
B Baudin ◽  
G Morgant ◽  
F C Baumann ◽  
J Giboudeau
Keyword(s):  
Angiotensin Converting Enzyme ◽  
Hormonal Regulation ◽  
Reference Interval ◽  
Healthy Children ◽  
Age Group ◽  
Converting Enzyme ◽  
Serum Angiotensin Converting Enzyme ◽  
Age Related ◽  
Ace Activity ◽  
Physiological Variations

Abstract Angiotensin-converting enzyme (ACE) was measured in serum of 187 healthy children between the ages six months and 18 years. Results were pooled for five-year age intervals and compared with the reference values for adults that we previously determined [Clin Chem 1986;32:884-6). Results for each age group were also studied as a function of sex. Children had higher ACE activities in serum than did adults (P less than 0.001), but these activities were age-related only from age four to 18 years. Adolescents showed sex-related differences, with higher serum ACE activities in boys than in girls (P less than 0.05). Both sex- and age-related differences may be related to a steroid hormonal regulation of ACE biosynthesis. We also verified that children with sarcoidosis (n = 20) had significantly increased serum ACE activity. Such physiological variations in serum ACE activity must be taken into account for diagnosing sarcoidosis in children, for following the course of the disease, and for evaluating the accuracy of therapy.

scholarly journals The potential role of serum angiotensin-converting enzyme in coronavirus disease 2019

2020 ◽  
Vol 20 (1) ◽  
Author(s):  
Zhe Zhu ◽  
Ting Cai ◽  
Lingyan Fan ◽  
Kehong Lou ◽  
Xin Hua ◽  
...  
Keyword(s):  
Angiotensin Converting Enzyme ◽  
Clinical Condition ◽  
Recovery Phase ◽  
Control Group ◽  
Converting Enzyme ◽  
Baseline Serum ◽  
Serum Angiotensin Converting Enzyme ◽  
Severe Group ◽  
Ace Activity

Abstract Background To explore the clinical significance of serum angiotensin-converting enzyme (ACE) activity in coronavirus disease 2019 (COVID-19). Methods In this retrospective study, a total of 136 consecutive patients with confirmed COVID-19 were recruited. Demographic and clinical data were recorded. The serum ACE activity was measured at baseline and during the recovery phase, and its relationship with clinical condition was analyzed. Results Of the 136 patients with confirmed COVID-19, the 16 severe patients were older and had a higher body mass index (BMI) and proportion of hypertension than the 120 nonsevere patients. In comparison to those of normal controls, the baseline serum ACE activities of subjects in the severe group and nonsevere group were decreased, with the lowest level in the severe group. However, the serum ACE activity increased in the recovery phase, and there were no significant differences among the severe group, nonsevere group and normal control group. Conclusion Serum ACE activity could be used as a marker to reflect the clinical condition of COVID-19 since low activity was associated with the severity of COVID-19 at baseline, and the activity increased with the remission of the disease.

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