scholarly journals Dry Eye Diseases and Ocular Surgery: Practical Guidelines for Canadian Eye Care Practitioners

2017 ◽  
Vol 79 (4) ◽  
pp. 19-33
Author(s):  
Paul M. Karpecki ◽  
C. Lisa Prokopich ◽  
Louis Racine ◽  
Etty Bitton ◽  
Barbara Caffery ◽  
...  
Keyword(s):  
Dry Eye ◽  
Surgical Outcomes ◽  
Eye Diseases ◽  
Eye Disease ◽  
Eye Care ◽  
Consensus Panel ◽  
Ocular Surgery ◽  
Before And After ◽  
Practical Guidelines ◽  
Patient At Risk

In 2014, the Canadian Dry Eye Disease Consensus Panel published Guidelines for screening, diagnosis and management of dry eye diseases (DED). These did not address the implications of DED for individuals who are being considered for or have recently undergone ocular surgery. DED is common in certain surgical cohorts, and the perisurgical setting poses specific challenges, both because surgery can complicate preexisting DED and because symptomatic and non-symptomatic DED place the patient at risk of poor surgical outcomes. The Consensus Panel has developed this Addendum to the 2014 Guidelines to offer guidance on DED care before and after ocular surgery.

scholarly journals Crosslinked hyaluronic acid with liposomes and crocin for management symptoms of dry eye disease caused by moderate meibomian gland dysfunction

2019 ◽  
Author(s):  
José-María Sánchez-González ◽  
Concepción De-Hita-Cantalejo ◽  
María Carmen Sánchez-González
Keyword(s):  
Hyaluronic Acid ◽  
Dry Eye ◽  
Meibomian Gland ◽  
Dry Eye Disease ◽  
Eye Disease ◽  
Schirmer Test ◽  
Ocular Surface Disease Index ◽  
Artificial Tear ◽  
Before And After ◽  
Contralateral Eye

Abstract Background: To study the effect of uncrosslinked and crosslinked hyaluronic acid combined with other artificial tear components in patients with dry eye caused by moderate meibomian gland dysfunction.Method: Prospective, single-blind, contralateral eye study. Fifty eyes were analyzed (25 patients). Eye selection for each tear type was random, and the eye drop formulations Aquoral Forte® (artificial tear A) and Aquoral Lipo® (artificial tear B) were used. The determined dosing schedule was three times a day for six weeks, and the study participants underwent a clinical examination before and 45 days after lubricant treatment. The Schirmer test, tear breakup time (TBUT) test, and Ocular Surface Disease Index (OSDI) questionnaire were applied before and after instillation period with both types of artificial tears. Results: On the Schirmer test, a significant improvement was obtained with both tear A (p < 0.01) and tear B (p < 0.01). On the TBUT test, a significant improvement was obtained with tear A (p < 0.01) and tear B (p < 0.01). The OSDI score significantly decreased after instillation period with both artificial tear types (p < 0.01). Conclusion: Uncrosslinked hyaluronic acid combined with other components, such as tamarind seed polysaccharide, and crosslinked hyaluronic acid combined with liposomes and crocin are effective for management symptoms of dry eye disease.

scholarly journals Apoptosis of conjunctival epithelial cells before and after the application of autologous serum eye drops in severe dry eye disease

2016 ◽  
Vol 160 (2) ◽  
pp. 271-275 ◽  
Author(s):  
Ivana Rybickova ◽  
Viera Vesela ◽  
Ivan Fales ◽  
Pavlina Skalicka ◽  
Katerina Jirsova
Keyword(s):  
Epithelial Cells ◽  
Dry Eye ◽  
Dry Eye Disease ◽  
Autologous Serum ◽  
Eye Disease ◽  
Eye Drops ◽  
Before And After ◽  
Serum Eye Drops ◽  
Conjunctival Epithelial Cells

scholarly journals Why Internists Should Care About Dry Eye Disease

2020 ◽  
Vol 9 (2) ◽  
pp. 532 ◽  
Author(s):  
Anat Galor
Keyword(s):  
Dry Eye ◽  
Dry Eye Disease ◽  
Eye Disease ◽  
Eye Care

Dry eye disease (DED) has been diagnosed and managed under the purview of the eye care professional, with internists typically not paying much attention to the condition [...]

Reducing omission of eye drops during hospital admission

2022 ◽  
pp. 1-7
Author(s):  
Charlotte S Ho ◽  
Darren SJ Ting ◽  
Devina Gogi
Keyword(s):  
Hospital Admission ◽  
Dry Eye ◽  
Substantial Reduction ◽  
Dry Eye Disease ◽  
National Standards ◽  
Eye Disease ◽  
Eye Drops ◽  
National Guidelines ◽  
Before And After

Background/aims Chronic ophthalmic conditions, such as glaucoma and dry eye disease, are frequently encountered debilitating eye conditions that can lead to substantial reduction in vision and quality of life. However, there is ongoing evidence to suggest that topical ophthalmic therapy is inappropriately omitted on admission to hospital. The primary aim of this audit was to investigate the trust adherence to the National Institute for Health and Care Excellence guideline on the prescribing standard of eye drops during hospital admission. The secondary aim was to raise awareness and ensure successful compliance with national standards to reduce unintentional omission of eye drops on admission and subsequent complications. Method Electronic medical records of all medical and surgical adult inpatients were studied prospectively on two different occasions. The quality of documentation of eye drops in clerking notes, the length of time taken between the admission and prescription of eye drops, and the accuracy of the prescription were examined. Following the initial audit, interventions focusing on clinician education were implemented. This includes highlighting the importance of eye drops in all departmental mandatory introductory sessions and putting up posters on all the wards as prompts. The same data collection method was used in the reaudit. Results In the initial audit, 64 (mean age 81.8±8.9 years) patients with regular prescriptions for eye drops were identified; 38 (59.4%) patients had eye drops for dry eye disease only, 20 (31.3%) patients had eye drops for glaucoma only, and six (9.4%) patients had eye drops for both. In the reaudit, 57 (mean age 76.7±15.3 years) patients were identified; 42 (73.7%) patients had eye drops for dry eye disease only, 10 (17.5%) patients had eye drops for glaucoma only, and five (8.8%) patients had eye drops for both. Following the intervention, there was a significant improvement in documentation of ocular diagnosis and eye drops on clerking notes from 41% to 65% (P=0.008), and eye drop reconciliation within 24 hours of admission improved from 45% to 75% (P=0.0008). All patients (100%) received the correct eye drop prescription before and after the intervention. Conclusions Education is effective in promoting adherence to national guidelines and reducing the incidence of inappropriate omission of eye drops on admission to hospital.

scholarly journals Transcutaneous Electrical Acupoint Stimulation (Teas) In The Treatment of Dry Eye Disease

2022 ◽  
Author(s):  
Xiaotong Ren ◽  
Jiarui Yang ◽  
Hao Yuan ◽  
Rong Zhang ◽  
Xuemin Li
Keyword(s):  
Dry Eye ◽  
Therapeutic Option ◽  
Signs And Symptoms ◽  
Dry Eye Disease ◽  
Eye Disease ◽  
Blurred Vision ◽  
Before And After ◽  
Peking University ◽  
Symptoms And Signs ◽  
Acupoint Stimulation

Abstract Purpose: To assess effectiveness and safety of the Transcutaneous Electrical Acupoint Stimulation (TEAS) treatment in alleviating symptoms and signs of dry eye disease (DED).Methods: Patients diagnosed with DED at the Peking University Third Hospital Eye Center from December 2020 to February 2021 were randomly assigned in a 1:1:1 ratio to 5mA, 3mA, or 0mA Group respectively. DED signs and symptoms were evaluated before and 30min after treatment. We compared the clinical improvement among the three groups and between each two groups. Results: A total of 63 patients were included. 5mA Group had best efficacy in all the signs and most of symptoms (P<0.05), and the symptoms scores in 3mA Group were also significantly improved after treatment except pain, watering and increased secretions (P<0.05). In the comparisons between before and after treatment between each two groups, 5mA Group showed greater improvement in the signs and most of symptoms than other two groups(P<0.05). In addition, 3mA Group had greater improvement than 0mA Group in the symptoms of asthenopia (P=0.018) and blurred vision (P=0.001). During the treatment, we hadn’t gotten any adverse events from patients.Conclusions: TEAS treatment was effective in the treatment of DED, and 5mA provided greater signs and symptoms relief. TEAS might be a new therapeutic option for the treatment of DED.

scholarly journals Dry eye disease ranking among common reasons for seeking eye care in a large US claims database

2019 ◽  
Vol Volume 13 ◽  
pp. 225-232 ◽  
Author(s):  
John L. Bradley ◽  
Ipek Özer Stillman ◽  
Irina Pivneva ◽  
Annie Guerin ◽  
Amber M. Evans ◽  
...  
Keyword(s):  
Dry Eye ◽  
Dry Eye Disease ◽  
Eye Disease ◽  
Eye Care ◽  
Claims Database

scholarly journals Assessment of Prevalence and Risk Factors of Dry Eye Disease among Study Group

2020 ◽  
Vol 9 (3) ◽  
pp. 1-4
Author(s):  
Madhavi Chevuturu
Keyword(s):  
Risk Factors ◽  
Dry Eye ◽  
Contact Lens ◽  
Dry Eye Disease ◽  
Eye Disease ◽  
Study Group ◽  
Ocular Allergy ◽  
Ocular Surgery ◽  
Steroid Use ◽  
The Difference

Background: Dry eye is a multifactorial disease of the tears and ocular surface that results in symptoms of discomfort, visual disturbance.   The present study was conducted to assess prevalence and risk factors of dry eye diseases among the study group. Subjects and Methods:  The present study was conducted from February 2018 to July 2018 on 184 patients of both genders visiting the Department of Ophthalmology Mediciti institute of medical sciences with eye complaints. Slit-lamp biomicroscopy with a cobalt blue filter was used to investigate the tear film layer, and the interval from the last blink to the appearance of the first random dry spot on the cornea was noted. Schirmer’s test was performed. Whatman filter paper no 41 was placed in the lower fornix at the lateral one-third of the lower lid margin. Results: Age groups 40-50 years had 52, 50-60 years had 98 and 60-70 years had 34 patients. There were 110 males and 74 females. The difference was significant (P< 0.05). 64 (58.1%) males and 40 (54%) had a dry eye disease. The prevalence found to be 61.9%. The severity of DED was mild in 25%, moderate in 46% and severe in 29%. The difference was significant (P< 0.05). Risk factors of DED were steroid use in 14%, smoking in 56%, alcoholism in 24%, computer job in 78%, systemic allergy in 4%, ocular allergy in 32%, contact lens use in 17% and previous ocular surgery in 7%. The difference was significant (P< 0.05). Conclusion: The author found that the prevalence rate of dry eyes was 61.9%. Risk factors of DED were steroid use, smoking, alcoholism, computer job, systemic allergy, ocular allergy, contact lens use and previous ocular surgery.

scholarly journals Lymphocytes in Dry Eye Disease

2021 ◽  
Author(s):  
Alicia Vázquez-Mendoza ◽  
Danielle Vannan ◽  
Evelin G. Morales ◽  
Marisol I. González ◽  
José Luis Reyes Hernández
Keyword(s):  
Immune Response ◽  
Dry Eye ◽  
Immune Cells ◽  
Inflammatory Diseases ◽  
Dry Eye Disease ◽  
Lymphocyte Subpopulations ◽  
Eye Diseases ◽  
Ocular Tissue ◽  
Eye Disease ◽  
Inflammatory Reactions

The eye is a delicate organ that, along with other tissues such as the testicles and brain, is considered immune-privileged. Immune cells that reside in the eye must create a tolerogenic microenvironment to prevent unwanted aggressive inflammatory reactions that can compromise function. However, the eye is exposed to persistent environmental insult that may overwhelm immune tolerance and result in eye diseases from diverse origins (autoimmune, infectious, and inflammatory). The immune system plays a central role in the different phases of eye diseases, as alterations in immune cells in response to mechanical, chemical, or infectious stimuli initiate and amplify the immune response that lead to ocular tissue damage. Both resident and infiltrating immune cells also actively inhibit the immune response and promote tissue repair. Emerging evidence is leading to a better understanding of how and when lymphocytes, amongst other immune cells, contribute to inflammatory diseases such as dry eye disease (DED). We have compiled literature identifying the presence and participation of lymphocyte subpopulations that modulate DED from studies in both mice and humans. Notably, most mouse studies have relied on desiccant-stress-induced models (non-autoimmune DED), whereas human studies are predominantly in patients with Sjögren’s syndrome (autoimmune DED).

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