scholarly journals Synapse-Assembly Proteins Maintain Synaptic Vesicle Cluster Stability and Regulate Synaptic Vesicle Transport inCaenorhabditis elegans

Genetics ◽  
2015 ◽  
Vol 201 (1) ◽  
pp. 91-116 ◽  
Author(s):  
Stacey L. Edwards ◽  
Rosalina M. Yorks ◽  
Logan M. Morrison ◽  
Christopher M. Hoover ◽  
Kenneth G. Miller
2002 ◽  
Vol 1 (1) ◽  
pp. 18-25 ◽  
Author(s):  
Megan Guziewicz ◽  
Toni Vitullo ◽  
Bethany Simmons ◽  
Rebecca Eustance Kohn

The goal of this laboratory exercise is to increase student understanding of the impact of nervous system function at both the organismal and cellular levels. This inquiry-based exercise is designed for an undergraduate course examining principles of cell biology. After observing the movement of Caenorhabditis elegans with defects in their nervous system, students examine the structure of the nervous system to categorize the type of defect. They distinguish between defects in synaptic vesicle transport and defects in synaptic vesicle fusion with membranes. The synaptic vesicles are tagged with green fluorescent protein (GFP), simplifying cellular analysis. The expected outcome of this experiment is that students will better understand the concepts of vesicle transport, neurotransmitter release, GFP, and the relation between the nervous system and behavior.


Toxicology ◽  
2013 ◽  
Vol 308 ◽  
pp. 50-59 ◽  
Author(s):  
Stéphane Lezmi ◽  
Najla Rokh ◽  
Gérard Saint-Macary ◽  
Michael Pino ◽  
Valérie Sallez ◽  
...  

2007 ◽  
Vol 10 (8) ◽  
pp. 980-989 ◽  
Author(s):  
Eunju Pack-Chung ◽  
Peri T Kurshan ◽  
Dion K Dickman ◽  
Thomas L Schwarz

2011 ◽  
Vol 71 (1) ◽  
pp. 71-77 ◽  
Author(s):  
Rafael Flores ◽  
Yuki Hirota ◽  
Brian Armstrong ◽  
Akira Sawa ◽  
Toshifumi Tomoda

PLoS Genetics ◽  
2014 ◽  
Vol 10 (10) ◽  
pp. e1004644 ◽  
Author(s):  
Qun Zheng ◽  
Shikha Ahlawat ◽  
Anneliese Schaefer ◽  
Tim Mahoney ◽  
Sandhya P. Koushika ◽  
...  

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