scholarly journals A Multilocus Sequence Survey inArabidopsis thalianaReveals a Genome-Wide Departure From a Neutral Model of DNA Sequence Polymorphism

Genetics ◽  
2005 ◽  
Vol 169 (3) ◽  
pp. 1601-1615 ◽  
Author(s):  
Karl J. Schmid ◽  
Sebastian Ramos-Onsins ◽  
Henriette Ringys-Beckstein ◽  
Bernd Weisshaar ◽  
Thomas Mitchell-Olds
Keyword(s):  
Dna Sequence ◽  
Sequence Polymorphism ◽  
Neutral Model ◽  
Genome Wide ◽  
A Genome ◽  
Dna Sequence Polymorphism

scholarly journals DNA Polymorphism in Lycopersicon and Crossing-Over per Physical Length

Genetics ◽  
1998 ◽  
Vol 150 (4) ◽  
pp. 1585-1593 ◽  
Author(s):  
Wolfgang Stephan ◽  
Charles H Langley
Keyword(s):  
Dna Sequence ◽  
Dna Polymorphism ◽  
Sequence Polymorphism ◽  
Breeding Systems ◽  
Crossing Over ◽  
Physical Length ◽  
Interspecific Divergence ◽  
Dna Sequence Polymorphism ◽  
Outcrossing Species ◽  
Genomic Regions

Abstract Surveys in Drosophila have consistently found reduced levels of DNA sequence polymorphism in genomic regions experiencing low crossing-over per physical length, while these same regions exhibit normal amounts of interspecific divergence. Here we show that for 36 loci across the genomes of eight Lycopersicon species, naturally occurring DNA polymorphism (scaled by locus-specific divergence between species) is positively correlated with the density of crossing-over per physical length. Large between-species differences in the amount of DNA sequence polymorphism reflect breeding systems: selfing species show much less within-species polymorphism than outcrossing species. The strongest association of expected heterozygosity with crossing-over is found in species with intermediate levels of average nucleotide diversity. All of these observations appear to be in qualitative agreement with the hitchhiking effects caused by the fixation of advantageous mutations and/or “background selection” against deleterious mutations.

Minisatellite mutation rate variation associated with a flanking DNA sequence polymorphism

1994 ◽  
Vol 8 (2) ◽  
pp. 162-170 ◽  
Author(s):  
Darren G. Monckton ◽  
Rita Neumann ◽  
Tara Guram ◽  
Neale Fretwell ◽  
Keiji Tamaki ◽  
...  
Keyword(s):  
Dna Sequence ◽  
Mutation Rate ◽  
Sequence Polymorphism ◽  
Rate Variation ◽  
Dna Sequence Polymorphism ◽  
Mutation Rate Variation
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