scholarly journals Evaluation of Neurocognitive Abilities in Patients Undergoing Carotid Endarterectomy Surgery

2021 ◽  
Vol 24 (1) ◽  
pp. E158-E164
Author(s):  
Zafer Cengiz Er ◽  
Kivanc Atilgan
Keyword(s):  
Carotid Endarterectomy ◽  
Cognitive Abilities ◽  
Test Score ◽  
Preoperative Period ◽  
Factors Affecting ◽  
Medicine Research ◽  
The Past ◽  
Neurocognitive Tests ◽  
The Mean ◽  
Learning Score

Objective: To evaluate the differences in neurocognitive abilities between the preoperative and postoperative periods following carotid endarterectomy (CEA), due to carotid artery stenosis, and to evaluate the effectiveness of CEA on neurocognitive abilities in the future. Material and methods: Thirty-eight cases of CEA surgery at Bozok University Faculty of Medicine Research Hospital between January 2015 and June 2020 were examined. Neurocognitive tests were performed on carotid endarterectomy patients one day before the operation and on the 2nd, 4th, and 30th postoperative days. The effect of CEA on cognitive results has been investigated. Results: Of the patients, eight were female (21.1%), 30 were male (78.9%), and the mean age was 66 ± 4.09. Thirty-two (84.21%) of the patients were operated on under general anesthesia and six (15.78%) under regional anesthesia. A shunt was used in 19 patients. Right carotid endarterectomy was performed in 20 cases and left carotid endarterectomy in 18 cases. We used the primary closure technique in two of 38 cases and patches on 36 of them. We used Dacron in 21 cases, PTFE in 12 cases, and saphenous vein as a patch in three cases. In the WMS digit spam and recall scores, the postoperative period fell on the 2nd day, and then on the 4th and 30th day after the operation, there was a low level of increase over time. Compared with the preoperative period, the learning score was found to be the lowest on the 2nd day, lower on the 4th day compared with the preoperative period and improved compared with the preoperative period on the 30th day. There was no decrease in the verbal fluency test score results after the operation, on the contrary, it was observed minimally. The test score results cumulatively were decreased in the early postoperative periods compared with the preoperative period and increased on the 30th day compared with the preoperative period. Conclusion: The purpose of CEA in the past was the prevention of ischemic stroke and cerebrovascular disease (CVD) rather than neurocognitive recovery. Factors affecting neurocognition in CEA are multifactorial. Preservation and improvement of neurocognition are more important than any other period of history. By prioritizing cognitive abilities in the treatment of carotid stenosis, individualization of the treatment will help maximize the increase in cognitive abilities by providing optimum benefit to the patient of each factor.

scholarly journals Donor demographics and factors affecting corneal utilisation in Eye Bank of North India

2021 ◽  
Vol 41 (5) ◽  
pp. 1773-1781
Author(s):  
S. K. Arya ◽  
Amit Raj ◽  
Jyoti Deswal ◽  
Piyush Kohli ◽  
Raghavendra Rai
Keyword(s):  
Age Groups ◽  
Tertiary Hospital ◽  
North India ◽  
Donor Age ◽  
Eye Bank ◽  
Factors Affecting ◽  
The Past ◽  
Northern India ◽  
The Mean ◽  
In The Beginning

Abstract Introduction Nearly 6.8 million people in India have vision less than 6/60 in at least one eye due to corneal diseases; of these, about a million had bilateral involvement. Purpose To identify the challenges faced; the trends in collection, storage and utilisation of corneal tissues in an eye bank in north India. Materials and methods The past records of Eye Bank linked to a tertiary hospital in northern India were analysed from November’1999 to October’2015 with respect to number of eye donations per year, donor demographics and utilisation of corneal tissues. Results The number of donations during the first 6 years were 100, 279 in the next 5 years and 473 in the last 5 years. The mean donor age was 63.2 ± 19.5 years. The percentage of donors less than 30, 31–60 and more than 60 years was 10%, 28% and 62%. Forty-two percent donations were from the hospital. The average time between the death and enucleation was 4.74 ± 5.31 hours. The percentage of corneas used in the donor age groups less than 30, 31–60 and above 60 years was 61.9%, 61.6% and 53.8%, respectively. The usability rate of the corneas from home and hospital was 63.7% and 55.3%, respectively. Conclusions The eye bank had a lukewarm response in the beginning, but gained momentum with time. The myths and beliefs prevalent in our society deter people from donating eyes freely. Each eye bank needs to individualise its problems and find solutions for adequate procurement and utilisation of tissue.

scholarly journals Manuscript Submission Patterns of Authors Publishing in Orthopaedic Sports Medicine Journals

2018 ◽  
Vol 6 (8) ◽  
pp. 232596711879175 ◽  
Author(s):  
Trevor J. Carver ◽  
Matthew J. Kraeutler ◽  
Keenan B. Amer ◽  
Eric C. McCarty
Keyword(s):  
Sports Medicine ◽  
Cross Sectional Study ◽  
Manuscript Submission ◽  
Cross Sectional ◽  
Medicine Research ◽  
The Past ◽  
Orthopaedic Journal ◽  
The Mean ◽  
Sports Traumatology ◽  
Publishing Journal

Background: Previous studies have examined the most cited articles in orthopaedic sports medicine research and the journals in which they were published. Purpose: To analyze the manuscript submission patterns of authors who published manuscripts in various orthopaedic sports medicine journals. Study Design: Cross-sectional study. Methods: All articles published in the March 2017 and April 2017 issues of Arthroscopy, the American Journal of Sports Medicine ( AJSM), Knee Surgery, Sports Traumatology, Arthroscopy ( KSSTA), and the Orthopaedic Journal of Sports Medicine ( OJSM) were searched. In addition, the past 50 sports medicine–related articles published in the Journal of Bone and Joint Surgery ( JBJS) dating back from April 2017 to May 2015 were searched. The corresponding author of each article was asked whether the publishing journal was the first journal of submission. If the article was previously submitted elsewhere, authors were asked which other journals, the dates of submission, and the order of submission. The proportion of articles that were initially submitted to each journal, the mean number of submissions prior to publication, and the mean duration from initial submission to date of publication were calculated for each journal. Results: A total of 298 articles were included in this study, and 221 (74%) corresponding authors responded to the survey. The mean number of submissions before acceptance was 1.05 for AJSM, 1.18 for JBJS, 1.20 for KSSTA, 1.38 for Arthroscopy, and 2.19 for OJSM. The percentage of articles that were submitted to their accepting journal first (ie, not previously submitted elsewhere) was 95% for AJSM, 85% for JBJS, 82% for KSSTA, 68% for Arthroscopy, and 13% for OJSM. Conclusion: Among the orthopaedic sports medicine journals included in this study, articles published in AJSM have the highest percentage of first submissions.

IMPROVING STUDENTS’ ACHIEVEMENT IN SPEAKING THROUGH TWO STAY TWO STRAY STRATEGY

2013 ◽  
Vol 2 (2) ◽  
Author(s):  
Dita Masyitah Sianipar And Sumarsih
Keyword(s):  
Action Research ◽  
Learning Process ◽  
Quantitative Data ◽  
Test Score ◽  
Qualitative Data ◽  
Speaking Test ◽  
The Subject ◽  
The Mean ◽  
Teaching Learning ◽  
The Way

This study deals with the way to improve students’ achievement in speaking particularly through Two Stay Two Stray Strategy. This study was conducted by using classroom action research. The subject of of the research was class X-AP SMK Swasta Harapan Danau Sijabut in Asahan Regency that consisted of 34 students. The research was conducted in two cycles consisted of three meetings in each cycle. The instruments of collecting data for quantitative data used Speaking Test and instrument for analysis of qualitative data used observation, interview and questionnaire sheet. Based on the speaking test score, students’ score kept improving in every test. In the test I the mean was 61,47, in the test II the mean was 67,41 and the test III the mean was 78,52. Based on observation sheet and questionnaire sheet, it was found that teaching learning process run well and lively. Students were active and interest in speaking. The using of Two Stay Two Stray Strategy is significantly improved students’ achievement in speaking.

Scrub typhus (Orientia tsutsugamushi), A rapidly spreading epidemic in Chennai - A standalone lab experience

2016 ◽  
Vol 5 (09) ◽  
pp. 4896
Author(s):  
Sripriya C.S.* ◽  
Shanthi B. ◽  
Arockia Doss S. ◽  
Antonie Raj I. ◽  
Mohana Priya
Keyword(s):  
Scrub Typhus ◽  
Clinical Symptoms ◽  
Clinical Manifestations ◽  
Febrile Illness ◽  
Orientia Tsutsugamushi ◽  
The Past ◽  
Igm Elisa ◽  
The Mean ◽  
Specific Symptoms ◽  
Symptoms And Signs

Scrub typhus (Orientia tsutsugamushi), is a strict intracellular bacterium which is reported to be a recent threat to parts of southern India. There is re-emergence of scrub typhus during the past few years in Chennai. Scrub typhus is an acute febrile illness which generally causes non-specific symptoms and signs. The clinical manifestations of this disease range from sub-clinical disease to organ failure to fatal disease. This study documents our laboratory experience in diagnosis of scrub typhus in patients with fever and suspected clinical symptoms of scrub typhus infection for a period of two years from April 2014 to April 2016 using immunochromatography and IgM ELISA methods. The study was conducted on 648 patients out of whom 188 patients were found to be positive for scrub typhus. Results also showed that pediatric (0 -12 years) and young adults (20 – 39 years) were more exposed to scrub typhus infection and female patients were more infected compared to male. The study also showed that the rate of infection was higher between September to February which also suggested that the infection rate is proportional to the climatic condition. Statistical analysis showed that the mean age of the patients in this study was 37.6, standard deviation was 18.97, CV % was 50.45. 

scholarly journals 797. Management of Patients with Multiple Clostridioides difficile Infection Recurrences using a Tapered-Pulsed Fidaxomicin Strategy

2020 ◽  
Vol 7 (Supplement_1) ◽  
pp. S441-S442
Author(s):  
Xing Tan ◽  
Andrew M Skinner ◽  
Benjamin Sirbu ◽  
Larry H Danziger ◽  
Dale N Gerding ◽  
...  
Keyword(s):  
First Episode ◽  
Initial Symptom ◽  
Once Daily ◽  
The Past ◽  
Clostridioides Difficile ◽  
Time To Recurrence ◽  
Clostridioides Difficile Infection ◽  
The Mean ◽  
Systemic Antibiotics

Abstract Background There is a paucity of data assessing outcomes of alternate fidaxomicin strategies in patients with recurrent Clostridioides difficile infection (rCDI). The objective of our study is to evaluate a tapered-pulsed (T-P) fidaxomicin regimen that was administered immediately following a course of CDI treatment with initial symptom resolution in patients with multiple rCDI. Methods We reviewed the characteristics and outcomes of 46 consecutive patients who received T-P fidaxomicin between January 1, 2014-June 30, 2019 in a specialty CDI clinic. The first episode in which fidaxomicin T-P was administered was analyzed. Failure was defined as the persistence of diarrhea and/or the need for additional CDI treatment at any time on T-P fidaxomicin. Sustained clinical cure (SCC) was defined as resolution of diarrhea without recurrence. Recurrence was defined as the return of diarrhea requiring retreatment with CDI therapy after completion of T-P fidaxomicin. Both SCC and recurrence were evaluated at 30 and 90 days after completion of T-P fidaxomicin. Results The mean±SD age of the 46 patients was 63.2±19.9 years, 71.7% were female, and the mean±SD CDI episodes within the past year was 3±1.4 . Most patients (73.9%) had previously failed a vancomycin tapered and/or pulsed regimen. Prior to administering T-P fidaxomicin, a treatment regimen was given to ensure resolution of symptoms. The CDI treatment most commonly used (58.7%) was vancomycin. The T-P fidaxomicin regimen used consisted of 200 mg given once daily for 7 days followed by 200 mg every other day for a median (min-max) duration of 33 (6-120) days. Two patients (4%) failed to respond to T-P fidaxomicin; 34 (74%) and 28 (61%) achieved SCC at 30 and 90 days, respectively. Among the 44 patients that successfully completed the T-P fidaxomicin regimen, recurrence developed in 10 (22.7%) and 16 (36.4%) of patients at 30 and 90 days, respectively, with a median (min-max) time to recurrence of 20 (3-87) days (Figure 1). Four patients with recurrence had received subsequent systemic antibiotics. Figure 1. Course of CDI therapy and follow-up Conclusion A tapered-pulsed fidaxomicin strategy may be effective in patients with multiply rCDI who are refractory to other treatments, including a vancomycin tapered and pulsed regimen. Disclosures Larry H. Danziger, PharmD, Merck (Speaker’s Bureau)

Open-wedge high tibial osteotomy in patients with discoid lateral meniscus

2021 ◽  
Vol 29 (2) ◽  
pp. 230949902110173
Author(s):  
Hee-June Kim ◽  
Ji-Yeon Shin ◽  
Hyun-Joo Lee ◽  
Chul-Hee Jung ◽  
Kyeong-Hyeon Park ◽  
...  
Keyword(s):  
High Tibial Osteotomy ◽  
Lateral Meniscus ◽  
Lateral Compartment ◽  
Clinical Results ◽  
Discoid Lateral Meniscus ◽  
Tibial Osteotomy ◽  
Open Wedge ◽  
Factors Affecting ◽  
The Mean ◽  
Open Wedge Hto

Background: There are concerns about the progression of the lateral osteoarthritis (OA) should be taken into account when high tibial osteotomy (HTO) is performed in patients with discoid lateral meniscus (LM). This study evaluated the clinical results of HTO in patients with discoid LM and elucidated factors affecting the results. Methods: This study evaluated 32 female patients with varus deformity and medial OA. Patients with discoid LM (8 patients) or without discoid LM (24 patients) underwent open-wedge HTO. The mean age was 53.5 years and the mean follow-up period was 35 months. Clinical results, including the Hospital for Special Surgery (HSS) score, Knee Society knee score (KS) and function score (FS), were evaluated. The progression of OA in the lateral compartment was also evaluated. Finally, we evaluated the factors affecting the clinical results and OA progression in the lateral compartment. Results: Between two groups, all clinical scores were not different (p = 0.964, 0.963, and 0.559, respectively). Three of eight patients (37.5%) in the discoid group developed OA in the lateral compartment, whereas 2 of 24 patients (8.3%) in the control group developed such; however, this was not significantly different (p = 0.085). In discoid group, patients with undercorrection has higher KS relative to patients with acceptable correction (p = 0.044). Other clinical results and OA change in the lateral compartment were not affected by evaluated factors. Conclusions: Patients who underwent open-wedge HTO showed the satisfactory clinical results and lateral OA progression regardless of the presence or absence discoid LM. However, when discoid LM was present, patients with undercorrection showed higher KS in comparison with patients with acceptable correction.

scholarly journals The features of the coastal fronts in the Eastern Guangdong coastal waters during the downwelling-favorable wind period

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Chaoyu Yang ◽  
Haibin Ye
Keyword(s):  
Coastal Waters ◽  
Meteorological Data ◽  
Pearson Correlation ◽  
Ocean Model ◽  
Ekman Pumping ◽  
Zonal Distribution ◽  
Factors Affecting ◽  
China Sea ◽  
Hybrid Coordinate Ocean Model ◽  
The Mean

AbstractA coastal front was detected in the eastern Guangdong (EGD) coastal waters during a downwelling-favorable wind period by using the diffuse attenuation coefficient at 490 nm (Kd(490)). Long-term satellite data, meteorological data and hydrographic data collected from 2003 to 2017 were jointly utilized to analyze the environmental factors affecting coastal fronts. The intensities of the coastal fronts were found to be associated with the downwelling intensity. The monthly mean Kd(490) anomalies in shallow coastal waters less than 25 m deep along the EGD coast and the monthly mean Ekman pumping velocities retrieved by the ERA5 dataset were negatively correlated, with a Pearson correlation of − 0.71. The fronts started in October, became weaker and gradually disappeared after January, extending southwestward from the southeastern coast of Guangdong Province to the Wanshan Archipelago in the South China Sea (SCS). The cross-frontal differences in the mean Kd(490) values could reach 3.7 m−1. Noticeable peaks were found in the meridional distribution of the mean Kd(490) values at 22.5°N and 22.2°N and in the zonal distribution of the mean Kd(490) values at 114.7°E and 114.4°E. The peaks tended to narrow as the latitude increased. The average coastal surface currents obtained from the global Hybrid Coordinate Ocean Model (HYCOM) showed that waters with high nutrient and sediment contents in the Fujian and Zhejiang coastal areas in the southern part of the East China Sea could flow into the SCS. The directions and lengths of the fronts were found to be associated with the flow advection.

Dimensions of Expertise in Wine Evaluation

2016 ◽  
Vol 12 (1) ◽  
pp. 59-83 ◽  
Author(s):  
Robert H. Ashton
Keyword(s):  
Cognitive Abilities ◽  
Jel Classification ◽  
Two Dimensions ◽  
Chemical Components ◽  
Component Level ◽  
The Past ◽  
Hedonic Evaluation ◽  
Expert Novice ◽  
Taste And Smell ◽  
Cognitive Dimensions

AbstractThis article explores the question of what distinguishes novices from experts in wine evaluation. Is it experts’ superior sensory abilities related to taste and smell, their superior cognitive abilities related to knowledge and memory, or a combination of both—and if a combination, which of the two dimensions of expertise, sensory or cognitive, seems to be more important? I address these issues by considering what has been learned in the past 30+ years from research concerning the sensory and cognitive dimensions of expertise in wine evaluation. The research examines expert/novice differences at both the chemical component level (detecting, discriminating among, and describing wine-relevant chemical components) and the holistic level (hedonic evaluation of wine as an integrated manifestation of its components). (JEL Classification: C93)

The prediction of voluntary intake of grazing dairy cows

1986 ◽  
Vol 107 (1) ◽  
pp. 43-54 ◽  
Author(s):  
Lindsey Caird ◽  
W. Holmes
Keyword(s):  
Organic Matter ◽  
Measurement Techniques ◽  
Live Weight ◽  
Simple Equation ◽  
Factors Affecting ◽  
Farm Planning ◽  
Sward Height ◽  
The Mean ◽  
Major Factors ◽  
Grazing Dairy Cows

SUMMARYInformation on the total organic matter intake, concentrates supplied (C), live weight (LW), week of lactation (WL), milk yield (MY), herbage organic matter digestibility (HOMD), herbage mass, sward height (SHT) or herbage allowance (HAL) measured individually for 357 cows at one of three sites was assembled. Observed intake was compared with intakes predicted by existing intake equations and new prediction equations based on regression models or regression and least-squares constants were developed. Major factors affecting intake were MY, LW, WL, C and HAL or SHT. Although HOMD was correlated with intake, better predictions were obtained when HOMD was omitted. There were differences between sites possibly associated with differences in measurement techniques.The predictive value of some existing equations and new equations were tested against independent sets of data. A simple equation (A) based on MY and LW (Ministry of Agriculture, Fisheries and Food, 1975) gave satisfactory average predictions but the mean square prediction error (MSPE) was high. The equations of Vadiveloo & Holmes (1979) adjusted for bias gave a relatively low MSPE. The preferred new equations for grazing cattle included MY, LW, WL, C and HAL or SHT, and their MSPE were similar to or lower than for indoor equations.The discussion indicates that a simple equation (A) would give adequate predictions for farm planning. The more detailed equations illustrate the inter-relations of animal with sward conditions and concentrate allowances. Predicted intakes may deviate from actual intakes because of short-term changes in body reserves.

Endovascular Advances for Extracranial Carotid Stenosis

Neurosurgery ◽  
2014 ◽  
Vol 74 (suppl_1) ◽  
pp. S92-S101 ◽  
Author(s):  
Jorge L. Eller ◽  
Travis M. Dumont ◽  
Grant C. Sorkin ◽  
Maxim Mokin ◽  
Elad I. Levy ◽  
...  
Keyword(s):  
Carotid Artery ◽  
Carotid Endarterectomy ◽  
Carotid Stenosis ◽  
Carotid Artery Stenosis ◽  
Carotid Artery Stenting ◽  
Carotid Stenting ◽  
Historical Background ◽  
Treatment Modalities ◽  
Endovascular Management ◽  
The Past

Abstract Carotid artery stenting has become a viable alternative to carotid endarterectomy in the management of carotid stenosis. Over the past 20 years, many trials have attempted to compare both treatment modalities and establish the indications for each one, depending on clinical and anatomic features presented by patients. Concurrently, carotid stenting techniques and devices have evolved and made endovascular management of carotid stenosis safe and effective. Among the most important innovations are devices for distal and proximal embolic protection and new stent designs. This paper reviews these advances in the endovascular management of carotid artery stenosis within the context of the historical background.

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