scholarly journals Bosentan Therapy in a Patient with Failed Fontan Procedure: A Case Report

2019 ◽  
Vol 22 (3) ◽  
pp. E213-E214
Author(s):  
Ting Lu ◽  
Mi Tang ◽  
Zhongshi Wu ◽  
Can Huang
Keyword(s):  
Case Report ◽  
Pleural Effusion ◽  
Pulmonary Artery ◽  
Fontan Procedure ◽  
Fontan Operation ◽  
Main Pulmonary Artery ◽  
Resistance Index ◽  
Endothelin 1 ◽  
Long Duration ◽  
Pulmonary Vascular Resistance Index

Background: Increased pulmonary vascular resistance index (PVR) leads to several complications in patients after a Fontan operation. This increase is mainly attributed to the overexpression of endothelin-1 for a long duration after the Fontan procedure. Here, we describe the case of a 3-year-old boy with a failed Fontan operation who was treated with bosentan, an endothelin-1 receptor blocker. Case report: Cardiac catheterization was performed, which showed a main pulmonary artery pressure (MPAP) of 19 mmHg and PVRI of 5.6 woods/m2. Oral bosentan regimen at a dose of 31.25 mg was initiated twice a day. The treatment was continued as pleural effusion and ascites persisted. No adverse events were observed, and the treatment was well tolerated. Pleural effusion disappeared, and ascites decreased markedly after 4 weeks, whereas the MPAP was 15 mmHg and the PVRI was 4.3 woods/m2. After 3 months of bosentan therapy, the MPAP was 12 mmHg and the PVRI was 4.1 woods/m2. Conclusion: We observed that bosentan reduces the PVRI and complications such as pleural effusion and ascites after a failed Fontan procedure.

scholarly journals Noninvasive Demonstration of Dual Coronary Artery Fistulas to Main Pulmonary Artery with 64-Slice Multidetector-Computed Tomography: A Case Report

2010 ◽  
Vol 2010 ◽  
pp. 1-4 ◽  
Author(s):  
Yoshiki Noda ◽  
Ryo Matsutera ◽  
Yoshinori Yasuoka ◽  
Haruhiko Abe ◽  
Hidenori Adachi ◽  
...  
Keyword(s):  
Computed Tomography ◽  
Case Report ◽  
Coronary Artery ◽  
Pulmonary Artery ◽  
Multidetector Computed Tomography ◽  
Coronary Sinus ◽  
Transthoracic Echocardiography ◽  
Adult Population ◽  
Main Pulmonary Artery ◽  
Coronary Artery Fistulas

Coronary artery fistulas, including coronary pulmonary fistulas, are usually discovered accidently among the adult population when undergoing invasive coronary angiographies. We report here a 58-year-old woman with dual fistulas originating from the left anterior descending coronary artery and right coronary sinus to the main pulmonary artery, demonstrating noninvasively with multidetector-computed tomography (MDCT) and transthoracic echocardiography (TTE).

Main pulmonary artery aneurysm with chronic rheumatic mitral stenosis: a case report

2015 ◽  
Vol 31 (1) ◽  
pp. 31-33
Author(s):  
Ramesh Chandra Mishra ◽  
Ramachandra Chandra Barik ◽  
Naresh Kumar Kalludi ◽  
Amaresh Rao Malempati
Keyword(s):  
Case Report ◽  
Pulmonary Artery ◽  
Mitral Stenosis ◽  
Main Pulmonary Artery ◽  
Artery Aneurysm ◽  
Pulmonary Artery Aneurysm ◽  
Rheumatic Mitral Stenosis

scholarly journals Cardiac Computed Tomography Angiography for Imaging Coronary Arteriovenous Malformation: a Case Report

2014 ◽  
Vol 60 (1) ◽  
pp. 22-24
Author(s):  
Suciu Zsuzsanna ◽  
Jakó Beáta ◽  
Benedek Theodora ◽  
Benedek I
Keyword(s):  
Computed Tomography ◽  
Case Report ◽  
Coronary Artery ◽  
Pulmonary Artery ◽  
Arteriovenous Malformation ◽  
Computed Tomography Angiography ◽  
Cardiac Computed Tomography ◽  
Main Pulmonary Artery ◽  
Cardiac Computed Tomography Angiography ◽  
Ionic Contrast

Abstract Background: Coronary arteriovenous malformation is a rare congenital disease consisting mainly in a direct communication between a coronary artery and any one of the four cardiac chambers, coronary sinus, pulmonary arteries or veins. This disease can lead to various cardiovascular events, their severity depending on the degree of the malformation. Case report: We present the case of a 56-year-old male patient, who was admitted to our institution with dyspnea, palpitation and chest pain, having a history of hypertension and hyperlipidemia, and an abnormal electrocardiogram. Physical examination did not reveal any alterations and the cardiac enzymes were in normal ranges. Cardiac computed tomography was performed before any other invasive studies, with a 64-row scanner (Somatom Sensation multislice 64 equipment, Siemens) after intravenous administration of non-ionic contrast material. CT scan revealed a large (2-2.5 mm) coronary fistula originating from the LAD to the main pulmonary artery, and multiple significant atherosclerotic coronary lesions. Coronary angiography confirmed the arteriovenous malformation between LAD and pulmonary artery, associated with three vascular coronary artery disease. Conclusions: Cardiac computed tomography angiography can help for a non-invasive diagnosis of the coronary artery malformations, in the same time revealing anatomic details which can be particulary useful for choosing the appropriate management strategy (surgical planning, interventional treatment or optimum medical treatment)

Anomalous Origin of the Right Coronary Artery from the Main Pulmonary Artery. A Case Report

Angiology ◽  
1994 ◽  
Vol 45 (4) ◽  
pp. 325-328 ◽  
Author(s):  
Carl Gustav Dahlström ◽  
Christer Hellekant ◽  
Bengt W. Johansson ◽  
Ulf Nyman
Keyword(s):  
Case Report ◽  
Coronary Artery ◽  
Pulmonary Artery ◽  
Right Coronary Artery ◽  
Main Pulmonary Artery ◽  
Anomalous Origin ◽  
The Right

Type A Intramural Hematoma Presenting with Acute Right Heart Failure Caused by Compression of the Main Pulmonary Artery: A Case Report

2009 ◽  
Vol 23 (4) ◽  
pp. 535.e11-535.e14 ◽  
Author(s):  
Mehmet Can ◽  
Ibrahim H. Tanboga ◽  
Taylan Akgun ◽  
Erdem Turkyilmaz ◽  
Soe M. Aung ◽  
...  
Keyword(s):  
Heart Failure ◽  
Case Report ◽  
Pulmonary Artery ◽  
Main Pulmonary Artery ◽  
Intramural Hematoma ◽  
Right Heart Failure ◽  
Type A ◽  
Right Heart
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