scholarly journals The Role of the Autoimmune Protocol (AIP) Diet to Improve Health Related Quality of Life and Disease Activity in Autoimmune Disease: A Review of the Current Clinical Evidence

2020 ◽  
Vol 4 (1) ◽  
Author(s):  
Robert D Abbott ◽  
Angela Alt ◽  
Mickey Trescott
Keyword(s):  
Quality Of Life ◽  
Autoimmune Disease ◽  
Disease Activity ◽  
Clinical Evidence ◽  
Health Related Quality ◽  
Related Quality ◽  
Health Related ◽  
Improve Health

Role of contextual factors in health-related quality of life in ankylosing spondylitis

2009 ◽  
Vol 69 (01) ◽  
pp. 108-112 ◽  
Author(s):  
V S Gordeev ◽  
W P Maksymowych ◽  
S M A A Evers ◽  
A Ament ◽  
L Schachna ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Ankylosing Spondylitis ◽  
Disease Activity ◽  
Contextual Factors ◽  
Health Related Quality ◽  
Related Quality ◽  
Health Related ◽  
The Impact

Background:In the bio-psycho-social model of health, the role of contextual factors, either environmental or personal, is recognised.Objective:To assess the impact of a number of contextual factors on self-reported disease-specific and generic health-related quality of life in patients with ankylosing spondylitis (AS).Methods:522 patients with AS from Canada and Australia completed a postal questionnaire including sociodemographic variables, disease activity (Bath Ankylosing Spondylitis Disease Activity Index (BASDAI)) function (Bath Ankylosing Spondylitis Functional Index (BASFI)) health-related quality of life (ASQoL and EQ-5D) and Rheumatoid Attitudes Index Helplessness Subscale. The contribution of contextual factors (nationality, ethnicity, marital status, education, employment and helplessness) in addition to functioning and disability (BASDAI and BASFI) to health-related quality of life was analysed using multivariate regression analyses. Interactions between contextual variables were explored.Results:Contextual factors explained 37% and 47% of the variance in EQ-5D and ASQoL, respectively. Helplessness and employment were the most important contextual factors. Their role was independent of the strong effect of disease activity (BASDAI) and functional limitations (BASFI). When ASQoL was the outcome, an interaction was seen between employment and education and when EQ-5D was the outcome, an interaction was seen between helplessness and education.Conclusions:Of the contextual factors explored in this study, helplessness and employment had an important and independent contribution to health-related quality of life. In patients with lower education, the effect of not being employed on ASQoL and the effect of helplessness on EQ-5D were stronger. Contextual factors, especially helplessness and employment, should receive more attention when interpreting data on health-related quality of life.

scholarly journals The effect of intravenous golimumab on health-related quality of life and work productivity in patients with active psoriatic arthritis: results of the Phase 3 GO-VIBRANT trial

2021 ◽  
Author(s):  
Alexis Ogdie ◽  
Jessica A. Walsh ◽  
Soumya D. Chakravarty ◽  
Steven Peterson ◽  
Kim Hung Lo ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Psoriatic Arthritis ◽  
Disease Activity ◽  
Productivity Loss ◽  
Health Related Quality ◽  
Functional Capability ◽  
Related Quality ◽  
Health Related ◽  
Eq Vas

Abstract Introduction/objectives To evaluate changes in health-related quality of life (HRQoL) and productivity following treatment with intravenous (IV) golimumab in patients with psoriatic arthritis (PsA). Methods Patients were randomized to IV golimumab 2 mg/kg (n=241) at Weeks 0, 4, then every 8 weeks (q8w) through Week 52 or placebo (n=239) at Weeks 0, 4, then q8w, with crossover to IV golimumab 2 mg/kg at Weeks 24, 28, then q8w through Week 52. Change from baseline in EuroQol-5 dimension-5 level (EQ-5D-5L) index and visual analog scale (EQ-VAS), daily productivity VAS, and the Work Limitations Questionnaire (WLQ) was assessed. Relationships between these outcomes and disease activity and patient functional capability were evaluated post hoc. Results At Week 8, change from baseline in EQ-5D-5L index (0.14 vs 0.04), EQ-VAS (17.16 vs 3.69), daily productivity VAS (−2.91 vs −0.71), and WLQ productivity loss score (−2.92 vs −0.78) was greater in the golimumab group versus the placebo group, respectively. At Week 52, change from baseline was similar in the golimumab and placebo-crossover groups (EQ-5D-5L index: 0.17 and 0.15; EQ-VAS: 21.61 and 20.84; daily productivity VAS: −2.89 and −3.31; WLQ productivity loss: −4.49 and −3.28, respectively). HRQoL and productivity were generally associated with disease activity and functional capability, with continued association from Week 8 through Week 52. Conclusion IV golimumab resulted in early and sustained improvements in HRQoL and productivity from Week 8 through 1 year in patients with PsA. HRQoL and productivity improvements were associated with improvements in disease activity and patient functional capability. Key Points• In patients with active psoriatic arthritis (PsA), intravenous (IV) golimumab improved health-related quality of life (HRQoL) and productivity as early as 8 weeks and maintained improvement through 1 year• Improvements in HRQoL and productivity outcomes in patients with PsA treated with IV golimumab were associated with improvements in disease activity and patient functional capability outcomes• IV golimumab is an effective treatment option for PsA that can mitigate the negative effects of the disease on HRQoL and productivity

Health-related quality of life in adult rhinitis: The role of perceived control of disease

2004 ◽  
Vol 114 (4) ◽  
pp. 845-850 ◽  
Author(s):  
Hubert Chen ◽  
Patricia P. Katz ◽  
Mark D. Eisner ◽  
Edward H. Yelin ◽  
Paul D. Blanc
Keyword(s):  
Quality Of Life ◽  
Perceived Control ◽  
Health Related Quality ◽  
Related Quality ◽  
Health Related

A Residential Summer Camp Can Reduce Body Fat and Improve Health-related Quality of Life in Obese Children

2013 ◽  
Vol 56 (1) ◽  
pp. 83-85 ◽  
Author(s):  
William W. Wong ◽  
Sarah E. Barlow ◽  
Carmen Mikhail ◽  
Theresa A. Wilson ◽  
Paula M. Hernandez ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Body Fat ◽  
Summer Camp ◽  
Health Related Quality ◽  
Obese Children ◽  
Related Quality ◽  
Health Related ◽  
Improve Health
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