Growth hormone treatment in Prader-Willi syndrome patients: systematic review and meta-analysis

2021 ◽  
Author(s):  
Caroline de Gouveia Buff Passone ◽  
Ruth Rocha Franco ◽  
Simone Sakura Ito ◽  
Evelinda Trindade ◽  
Michel Polak ◽  
...  
Keyword(s):  
Systematic Review ◽  
Growth Hormone ◽  
Growth Hormone Treatment ◽  
Meta Analysis ◽  
Hormone Treatment ◽  
Prader Willi Syndrome

The effect of growth hormone treatment or physical training on motor performance in Prader–Willi syndrome: A systematic review

2012 ◽  
Vol 36 (8) ◽  
pp. 1817-1838 ◽  
Author(s):  
Linda Reus ◽  
Leo A. van Vlimmeren ◽  
J. Bart Staal ◽  
Barto J. Otten ◽  
Maria W.G. Nijhuis-van der Sanden
Keyword(s):  
Systematic Review ◽  
Growth Hormone ◽  
Physical Training ◽  
Motor Performance ◽  
Growth Hormone Treatment ◽  
Hormone Treatment ◽  
Prader Willi Syndrome

scholarly journals Growth hormone treatment for adults with Prader-Willi syndrome: A meta-analysis

2021 ◽  
Author(s):  
Anna Rosenberg ◽  
Caroline Passone ◽  
Karlijn Pellikaan ◽  
Durval Damiani ◽  
Jan Van der Lely Aart ◽  
...  
Keyword(s):  
Growth Hormone ◽  
Growth Hormone Treatment ◽  
Meta Analysis ◽  
Hormone Treatment ◽  
Prader Willi Syndrome

scholarly journals Effects of Childhood Multidisciplinary Care and Growth Hormone Treatment on Health Problems in Adults with Prader-Willi Syndrome

2021 ◽  
Vol 10 (15) ◽  
pp. 3250
Author(s):  
Karlijn Pellikaan ◽  
Anna G. W. Rosenberg ◽  
Kirsten Davidse ◽  
Anja A. Kattentidt-Mouravieva ◽  
Rogier Kersseboom ◽  
...  
Keyword(s):  
Growth Hormone ◽  
Growth Hormone Treatment ◽  
Multidisciplinary Care ◽  
Hormone Treatment ◽  
Health Problems ◽  
Pituitary Hormone ◽  
Childhood And Adolescence ◽  
Prader Willi Syndrome ◽  
Adult Age ◽  
Beneficial Effects

Prader-Willi syndrome (PWS) is a complex hypothalamic disorder. Features of PWS include hyperphagia, hypotonia, intellectual disability, and pituitary hormone deficiencies. The combination of growth hormone treatment and multidisciplinary care (GHMDc) has greatly improved the health of children with PWS. Little is known about the effects of childhood GHMDc on health outcomes in adulthood. We retrospectively collected clinical data of 109 adults with PWS. Thirty-nine had received GHMDc during childhood and adolescence (GHMDc+ group) and sixty-three had never received growth hormone treatment (GHt) nor multidisciplinary care (GHMDc− group). Our systematic screening revealed fewer undetected health problems in the GHMDc+ group (10%) than in the GHMDc− group (84%). All health problems revealed in the GHMDc+ group had developed between the last visit to the paediatric and the first visit to the adult clinic and/or did not require treatment. Mean BMI and the prevalence of diabetes mellitus type 2 were significantly lower in the GHMDc+ group compared to the GHMDc− group. As all patients who received GHt were treated in a multidisciplinary setting, it is unknown which effects are the result of GHt and which are the result of multidisciplinary care. However, our data clearly show that the combination of both has beneficial effects. Therefore, we recommend continuing GHMDc after patients with PWS have reached adult age.

scholarly journals Effects of growth hormone treatment in adults with Prader–Willi syndrome

2013 ◽  
Vol 23 (3) ◽  
pp. 81-87 ◽  
Author(s):  
M.G. Butler ◽  
B.K. Smith ◽  
J. Lee ◽  
C. Gibson ◽  
C. Schmoll ◽  
...  
Keyword(s):  
Growth Hormone ◽  
Growth Hormone Treatment ◽  
Hormone Treatment ◽  
Prader Willi Syndrome

scholarly journals Low dose growth hormone treatment in infants and toddlers with Prader-Willi syndrome is comparable to higher dosage regimens

2017 ◽  
Vol 34 ◽  
pp. 1-7 ◽  
Author(s):  
Elly Scheermeyer ◽  
Mark Harris ◽  
Ian Hughes ◽  
Patricia A. Crock ◽  
Geoffrey Ambler ◽  
...  
Keyword(s):  
Growth Hormone ◽  
Low Dose ◽  
Growth Hormone Treatment ◽  
Hormone Treatment ◽  
Prader Willi Syndrome ◽  
Infants And Toddlers ◽  
Dosage Regimens
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