scholarly journals 8th edition of the AJCC/TNM staging system of thyroid cancer: what to expect (ITCO#2)

2018 ◽  
Vol 25 (3) ◽  
pp. L7-L11 ◽  
Author(s):  
Livia Lamartina ◽  
Giorgio Grani ◽  
Emanuela Arvat ◽  
Alice Nervo ◽  
Maria Chiara Zatelli ◽  
...  
Keyword(s):  
Thyroid Cancer ◽  
Staging System ◽  
Tnm Staging ◽  
Tnm Staging System ◽  
8Th Edition

The Updated AJCC/TNM Staging System for Papillary Thyroid Cancer (8th Edition): From the Perspective of Genomic Analysis

2018 ◽  
Vol 42 (11) ◽  
pp. 3624-3631 ◽  
Author(s):  
Kyubo Kim ◽  
Jin Hwan Kim ◽  
Il Seok Park ◽  
Young Soo Rho ◽  
Gee Hwan Kwon ◽  
...  
Keyword(s):  
Thyroid Cancer ◽  
Papillary Thyroid Cancer ◽  
Genomic Analysis ◽  
Staging System ◽  
Tnm Staging ◽  
Papillary Thyroid ◽  
Tnm Staging System ◽  
8Th Edition

HOW DOES THE AJCC/TNM STAGING SYSTEM 8TH EDITION PERFORM IN THYROID CANCER AT A MAJOR MIDDLE EASTERN MEDICAL CENTER?

2020 ◽  
Author(s):  
Ali S. Alzahrani ◽  
Lina Albalawi ◽  
Sedra Mazi ◽  
Noha Mukhtar ◽  
Hadeel AlJamei ◽  
...  
Keyword(s):  
Thyroid Cancer ◽  
Medical Center ◽  
Middle Eastern ◽  
Staging System ◽  
Tnm Staging ◽  
Tnm Staging System ◽  
8Th Edition

scholarly journals Comparison of long-term prognosis for differentiated thyroid cancer according to the 7th and 8th editions of the AJCC/UICC TNM staging system

2020 ◽  
Vol 11 ◽  
pp. 204201882092101 ◽  
Author(s):  
Kwangsoon Kim ◽  
Jin Kyong Kim ◽  
Cho Rok Lee ◽  
Sang-Wook Kang ◽  
Jandee Lee ◽  
...  
Keyword(s):  
Thyroid Cancer ◽  
Differentiated Thyroid Cancer ◽  
Disease Free Survival ◽  
Staging System ◽  
Tnm Staging ◽  
University Hospital ◽  
Tnm Staging System ◽  
Staging Systems ◽  
8Th Edition

Background: The 8th edition of the American Joint Committee on Cancer/Union for International Cancer Control (AJCC/UICC) tumor-node-metastasis (TNM) staging system was released with major revisions. The purpose of this retrospective study was to investigate differences between the 7th and 8th editions of the AJCC/UICC TNM staging system and to compare the predictability of prognosis between the two staging systems with patients who underwent thyroidectomy for differentiated thyroid cancer (DTC) at a single institution. Methods: A total of 3238 patients underwent thyroid operation from January 2002 to December 2006 at Yonsei University Hospital (Seoul, Korea), of which 2294 with complete clinical data and sustained follow up were enrolled. Clinicopathologic features and TNM staging by applying the 7th and 8th editions of the AJCC/UICC were analyzed retrospectively by the complete review of medical charts and pathology reports of patients. Mean follow-up duration was 132.9 ± 27.9 months. Results: A significant number of T3 patients were downstaged to T1 (838, 36.5%) and T2 (122, 5.3%). After applying the 8th edition of the AJCC/UICC TNM staging system, the number of stage I patients increased significantly from 1434 (62.5%) to 2058 (89.7%), whereas numbers of stage III and IV patients decreased significantly from 644 (28.1%) to 33 (1.4%) and from 199 (8.7%) to 17 (0.7%), respectively. According to Kaplan–Meier survival analyses and values of the Harrell’s c-index and integrated area under the curve (iAUC), the 8th edition has significantly better predictive performance for disease-free survival (DFS) and disease-specific survival (DSS) than the 7th edition. Conclusions: A significant population was downstaged after applying the 8th edition of the AJCC/UICC TNM staging system, and the 8th edition provided significantly better accuracy in predicting DFS and DSS in patients with DTC.

scholarly journals Impacts of the American Joint Committee on Cancer (AJCC) 8th edition tumor, node, metastasis (TNM) staging system on outcomes of differentiated thyroid cancer in Thai patients

Heliyon ◽  
2021 ◽  
Vol 7 (3) ◽  
pp. e06624
Author(s):  
Yotsapon Thewjitcharoen ◽  
Waralee Chatchomchuan ◽  
Krittadhee Karndumri ◽  
Sriurai Porramatikul ◽  
Sirinate Krittiyawong ◽  
...  
Keyword(s):  
Thyroid Cancer ◽  
Differentiated Thyroid Cancer ◽  
Staging System ◽  
Tnm Staging ◽  
Tumor Node Metastasis ◽  
Node Metastasis ◽  
American Joint Committee ◽  
Tnm Staging System ◽  
8Th Edition

Finding the Optimal Age Cutoff for the UICC/AJCC TNM Staging System in Patients with Papillary or Follicular Thyroid Cancer

Thyroid ◽  
2021 ◽  
Author(s):  
Evert F.S. van Velsen ◽  
W. Edward Visser ◽  
Merel Tessa Stegenga ◽  
Uwe Maeder ◽  
Christoph Reiners ◽  
...  
Keyword(s):  
Thyroid Cancer ◽  
Staging System ◽  
Tnm Staging ◽  
Follicular Thyroid Cancer ◽  
Tnm Staging System

RA09.08: EVALUATION OF THE EIGHTH YPTNM CLASSIFICATION SYSTEM IN ESOPHAGEAL CANCER PATIENTS

2018 ◽  
Vol 31 (Supplement_1) ◽  
pp. 41-42
Author(s):  
Motoo Nomura ◽  
Shigeru Tsunoda ◽  
Katsuyuki Sakanaka ◽  
Masashi Tamaoki ◽  
Yusuke Amanuma ◽  
...  
Keyword(s):  
Staging System ◽  
Tnm Staging ◽  
Prognostic Impact ◽  
Poor Prognostic Factor ◽  
Pathologic Stage ◽  
7Th Edition ◽  
Tnm Staging System ◽  
Staging Systems ◽  
Prognostic Group ◽  
8Th Edition

Abstract Background The 7th edition of the Union for International Cancer Control (UICC) TNM staging system is based on pathologic data from esophageal cancers treated by surgery alone. In the 8th edition of UICC-TNM staging system, there is no information available for treatment modality (surgery alone or neoadjuvant therapy [NAC] followed by surgery [NAC-S]), although clinical stage, neoadjuvant pathologic stage, and pathologic stage were analyzed and identified. The objective of this study was to evaluate the prognostic impact of the new staging system on esophageal squamous cell cancer (ESCC) patients treated by NAC-S. Methods Database of 140 consecutive ESCC patients in our hospital was retrospectively restaged in 7th and 8th UICC-TNM system. The prognostic impacts of pathologic stage after NAC according to the both staging systems were compared. Results The median follow-up period was 4.8 years (range 0.2–9.7), with 49 patients dead at the time of analysis. In 7th edition, the 3-year overall survival rates (3y-OS) of ypStages 0, I, II, III, and IV were 100%, 93.5%, 93.5%, 43.9%, and 0.0%, respectively. In 8th edition, the 3y-OS of ypStages 0, I, II, III, and IV were 100%, 96.5%, 90.2%, 51.7%, and 29.6%, respectively. There were no marked differences between 7th and 8th edition in the prognoses. The both editions poorly distinguish the prognoses of ypStages 0, I, and II. For pathological prognostic group in 7th edition, the 3y-OS of Groups 0, I, II, III, and IV were 100%, 97.0%, 90.6%, 43.9%, and 0.0%, respectively. For pathological prognostic group in 8th edition, the 3y-OS of Groups 0, I, II, III, and IV were 100%, 96.7%, 89.8%, 51.7%, and 29.6%, respectively. For patients with ypStages 0-II, pretreatment higher CEA was poor prognostic factor (HR 7.1, 95% confidence interval 1.9–25.9). Conclusion Our study indicates the problem that the ypStage in the 8th TNM staging system poorly distinguish the prognoses of ypStages 0, I, and II in patients undergoing NAC-S. Additional study is needed to evaluate the role of ypStage 0-II incorporation of new prognostic factors. Disclosure All authors have declared no conflicts of interest.

scholarly journals The New TNM Staging System for Thyroid Cancer and the Risk of Disease Downstaging

2018 ◽  
Vol 9 ◽  
Author(s):  
Claudio Casella ◽  
Silvia Ministrini ◽  
Alessandro Galani ◽  
Francesco Mastriale ◽  
Carlo Cappelli ◽  
...  
Keyword(s):  
Thyroid Cancer ◽  
Staging System ◽  
Tnm Staging ◽  
Tnm Staging System ◽  
Risk Of Disease
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