Vitamin D intake and status in children 2-18 years: a meta-analysis

2017 ◽  
Author(s):  
Neil Brett ◽  
Hope Weiler
Keyword(s):  
Vitamin D ◽  
Meta Analysis ◽  
Vitamin D Intake

Association between vitamin D intake and the risk of rheumatoid arthritis: a meta-analysis

2012 ◽  
Vol 31 (12) ◽  
pp. 1733-1739 ◽  
Author(s):  
Gwan Gyu Song ◽  
Sang-Cheol Bae ◽  
Young Ho Lee
Keyword(s):  
Rheumatoid Arthritis ◽  
Vitamin D ◽  
Meta Analysis ◽  
Vitamin D Intake

25-Hydroxyvitamin D level, vitamin D intake, and risk of stroke: A dose–response meta-analysis

2020 ◽  
Vol 39 (7) ◽  
pp. 2025-2034 ◽  
Author(s):  
Han Shi ◽  
Hanze Chen ◽  
Yun Zhang ◽  
Jinwei Li ◽  
Kailei Fu ◽  
...  
Keyword(s):  
Vitamin D ◽  
Dose Response ◽  
Meta Analysis ◽  
Hydroxyvitamin D ◽  
Vitamin D Intake ◽  
25 Hydroxyvitamin D

Association Between Vitamin D and Risk of Colorectal Cancer: A Systematic Review of Prospective Studies

2011 ◽  
Vol 29 (28) ◽  
pp. 3775-3782 ◽  
Author(s):  
Yanlei Ma ◽  
Peng Zhang ◽  
Feng Wang ◽  
Jianjun Yang ◽  
Zhihua Liu ◽  
...  
Keyword(s):  
Colorectal Cancer ◽  
Systematic Review ◽  
Rectal Cancer ◽  
Vitamin D ◽  
Prospective Studies ◽  
Meta Analysis ◽  
Blood Levels ◽  
Hydroxyvitamin D ◽  
Vitamin D Intake ◽  
25 Hydroxyvitamin D

Purpose To conduct a systematic review of prospective studies assessing the association of vitamin D intake or blood levels of 25-hydroxyvitamin D [25(OH)D] with the risk of colorectal cancer using meta-analysis. Methods Relevant studies were identified by a search of MEDLINE and EMBASE databases before October 2010 with no restrictions. We included prospective studies that reported relative risk (RR) estimates with 95% CIs for the association between vitamin D intake or blood 25(OH)D levels and the risk of colorectal, colon, or rectal cancer. Approximately 1,000,000 participants from several countries were included in this analysis. Results Nine studies on vitamin D intake and nine studies on blood 25(OH)D levels were included in the meta-analysis. The pooled RRs of colorectal cancer for the highest versus lowest categories of vitamin D intake and blood 25(OH)D levels were 0.88 (95% CI, 0.80 to 0.96) and 0.67 (95% CI, 0.54 to 0.80), respectively. There was no heterogeneity among studies of vitamin D intake (P = .19) or among studies of blood 25(OH)D levels (P = .96). A 10 ng/mL increment in blood 25(OH)D level conferred an RR of 0.74 (95% CI, 0.63 to 0.89). Conclusion Vitamin D intake and blood 25(OH)D levels were inversely associated with the risk of colorectal cancer in this meta-analysis.

scholarly journals Association Between Vitamin D Exposure and Head and Neck Cancer: A Systematic Review With Meta-Analysis

2021 ◽  
Vol 12 ◽  
Author(s):  
Yuting Pu ◽  
Gangcai Zhu ◽  
Yimin Xu ◽  
Siyuan Zheng ◽  
Bin Tang ◽  
...  
Keyword(s):  
Systematic Review ◽  
Vitamin D ◽  
Head And Neck Cancer ◽  
Head And Neck ◽  
Meta Analysis ◽  
Hydroxyvitamin D ◽  
Vitamin D Intake ◽  
25 Hydroxyvitamin D ◽  
High Concentrations

BackgroundVitamin D deficiency is a well-described preventable cause of many cancers; the association of vitamin D use with the development of head and neck cancer (HNC) is not clear. We aim to conduct a systematic review of the studies assessing the relation between vitamin D exposure and the prevention and prognosis of the HNC using meta-analysis.MethodsPubMed, EMBASE, Cochrane Library, Web of Science up to 1 January 2021, and reference lists of related studies were searched. We extracted observational studies reporting the association between vitamin D (vitamin D receptor gene polymorphisms, 25-hydroxyvitamin D concentrations, and vitamin D intake) and the outcomes of interest (HNC incidence and HNC mortality) in HNC patients aged 18 or older. Fixed effects models were used to calculate pooled effect sizes and 95% confidence intervals (CIs) by RevMan (version 5.3).ResultsSixteen studies with a total of 81,908 participants were enrolled in our meta-analysis. Based on the pooled genomic analysis, comparing with participants with the genotypes of Ff + FF or FF, the pooled odds ratio (OR) of participants with the genotype of ff was 0.77 (95% CI: 0.61 to 0.97) and 0.75 (0.58 to 0.97), respectively. A similar trend was noted when comparing tt with Tt + TT or TT, in which OR (95% CI) was 0.70 (0.55 to 0.90) and 0.72 (0.55 to 0.95). No significant association was identified between BsmI polymorphism and HNC. Furthermore, the OR of HNC incidence was 0.77 (0.65 to 0.92) for participants with vitamin D intake over the ones with a regular diet. High concentrations of circulated 25-hydroxyvitamin D (25-OHD) significantly decreased by 32% of HNC incidence (OR (95% CI): 0.68 (0.59 to 0.78)) and increased HNC survival (pooled hazard ratio 1.13, 1.05 to 1.22) during a 4–5 years follow-up. High concentrations of circulating 25-OHD in patients with HNC led to a decreased risk of mortality to 0.75 (0.60 to 0.94) as the follow-up extends to 8–12 years.ConclusionsElevated activities of vitamin D by diet intake, genomic polymorphisms, or circulated 25-OHD may protect people from HNC and improve the prognosis of patients with HNC.Systematic Review RegistrationPROSPERO, identifier CRD42020176002 (https://www.crd.york.ac.uk/PROSPERO/display_record.php?RecordID=176002).

The Role of Vitamin D on the Prognosis and Incidence of Lung Cancer: A Systematic Review and Meta-Analysis

2021 ◽  
Author(s):  
Mingxia Qian ◽  
Dina Guo ◽  
Rongrong Fu ◽  
Shuping Qi ◽  
Xiaojun Fu ◽  
...  
Keyword(s):  
Lung Cancer ◽  
Vitamin D ◽  
Cancer Patients ◽  
Meta Analysis ◽  
Cochrane Library ◽  
Term Survival ◽  
Long Term Survival ◽  
Lung Cancer Patients ◽  
Vitamin D Intake

Abstract Background: The correlation between vitamin D intake and lung cancer development is controversial. This meta-analysis aims to evaluate the relationship between vitamin D and the prognosis and incidence of lung cancer. Methods: A comprehensive database search on Pubmed, Web of Science, EBSCO, and Cochrane Library was carried out from the beginning to November 2020. Long-term survival and the incidence rate of patients with lung cancer were the primary outcomes of the study. Results: Ten eligible studies were selected for the meta-analysis following specific inclusion and exclusion criteria. Four included studies, covering 5007 patients, compared the overall survival (OS) and relapse-free survival (RFS) of lung cancer patients among total vitamin D users with non-users. Significantly, the estimated pooled hazard ratio (HR) revealed that vitamin D could improve OS and RFS of lung cancer patients [HR=0.83, 95% CI (0.72-0.95); HR=0.79, 95% CI (0.61-0.97), respectively]. Vitamin D intake was inversely associated with lung cancer incidence in six studies [OR=0.90, 95% CI (0.83-0.97)]. Conclusions: The present meta-analysis shows vitamin D not only improves the long-term survival of lung cancer patients but has a beneficial effect on the incidence of lung cancer. Notwithstanding, more studies are needed to confirm the study results.

scholarly journals Vitamin D Intake and the Risk of Colorectal Cancer: An Updated Meta-Analysis and Systematic Review of Case-Control and Prospective Cohort Studies

Cancers ◽  
2021 ◽  
Vol 13 (11) ◽  
pp. 2814
Author(s):  
Hatim Boughanem ◽  
Silvia Canudas ◽  
Pablo Hernandez-Alonso ◽  
Nerea Becerra-Tomás ◽  
Nancy Babio ◽  
...  
Keyword(s):  
Colorectal Cancer ◽  
Vitamin D ◽  
Confidence Interval ◽  
Prospective Studies ◽  
Meta Analysis ◽  
Case Control ◽  
Dietary Vitamin ◽  
Case Control Studies ◽  
Vitamin D Intake ◽  
Dietary Vitamin D

Obesity, a sedentary lifestyle, high red meat consumption and alcohol, and tobacco are considered the driving factors behind colorectal cancer (CRC) worldwide. Both diet and lifestyle are recognized to play an important role in the prevention of CRC. Forty years later, the vitamin D–cancer hypothesis is considered consistent. However, the relationship between low vitamin D intake and CRC is still controversial. The aim of this meta-analysis is to determine the associations between Vitamin D intake and CRC. MEDLINE-PubMed and Cochrane databases were searched up to May 2020 for studies evaluating the association between vitamin D intake (from foods and supplements) and CRC. Two reviewers, working independently, screened all titles and abstracts to identify the studies that met the inclusion criteria (case-control or prospective cohort (PC) studies published in English). Data were pooled by the generic inverse variance method using a random or fixed effect model. Heterogeneity was identified using the Cochran Q-test and quantified by the I2 statistic. A total of 31 original studies were included for the quantitative meta-analysis, comprising a total 47.540 cases and 70.567 controls in case-control studies, and a total of 14.676 CRC-incident cases (out of 808.130 subjects in PC studies) from 17 countries. A significant 25% lower risk was reported comparing the highest vs. the lowest dietary vitamin D consumption and CRC risk (odds ratio (95% confidence interval): 0.75 (0.67; 0.85)) in case-control studies, whereas a non-significant association was reported in case of prospective studies (hazard ratio (95% confidence interval): 0.94 (0.79; 1.11). The present meta-analysis demonstrates that high dietary vitamin D is associated to CRC prevention. However, larger and high-quality prospective studies and clinical trials are warranted to confirm this association.

scholarly journals Global Perspective of the Vitamin D Status of African-Caribbean Populations: A Systematic Review and Meta-analysis

2021 ◽  
Author(s):  
Rebecca M. Vearing ◽  
Kathryn H. Hart ◽  
Andrea L. Darling ◽  
Yasmine Probst ◽  
Aminat S. Olayinka ◽  
...  
Keyword(s):  
Systematic Review ◽  
Vitamin D ◽  
Dietary Intake ◽  
Meta Analysis ◽  
Dietary Vitamin ◽  
Vitamin D Status ◽  
Vitamin D Intake ◽  
African Caribbean ◽  
Dietary Vitamin D ◽  
Caribbean Populations

Abstract Background/Objectives Vitamin D deficiency remains a global public health issue, particularly in minority ethnic groups. This review investigates the vitamin D status (as measured by 25(OH)D and dietary intake) of the African-Caribbean population globally. Subjects/Methods A systematic review was conducted by searching key databases (PUBMED, Web of Science, Scopus) from inception until October 2019. Search terms included ‘Vitamin D status’ and ‘African-Caribbean’. A random effects and fixed effects meta-analysis was performed by combining means and standard error of the mean. Result The search yielded 19 papers that included n = 5670 African-Caribbean participants from six countries. A meta-analysis found this population to have sufficient (>50 nmol/L) 25(OH)D levels at 67.8 nmol/L, 95% CI (57.9, 7.6) but poor dietary intake of vitamin D at only 3.0 µg/day, 95% CI (1.67,4.31). For those living at low latitudes ‘insufficient’ (as defined by study authors) 25(OH)D levels were found only in participants with type 2 diabetes and in those undergoing haemodialysis. Suboptimal dietary vitamin D intake (according to the UK recommended nutrient intake of 10 µg/day) was reported in all studies at high latitudes. Studies at lower latitudes, with lower recommended dietary intakes (Caribbean recommended dietary intake: 2.5 µg/day) found ‘sufficient’ intake in two out of three studies. Conclusions 25(OH)D sufficiency was found in African-Caribbean populations at lower latitudes. However, at higher latitudes, 25(OH)D deficiency and low dietary vitamin D intake was prevalent.

scholarly journals Vitamin D intake, blood vitamin D levels, and the risk of breast cancer: a dose-response meta-analysis of observational studies

Aging ◽  
2019 ◽  
Vol 11 (24) ◽  
pp. 12708-12732 ◽  
Author(s):  
Dingli Song ◽  
Yujiao Deng ◽  
Kang Liu ◽  
Linghui Zhou ◽  
Na Li ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Vitamin D ◽  
Dose Response ◽  
Observational Studies ◽  
Meta Analysis ◽  
Vitamin D Intake ◽  
Vitamin D Levels
Sign in / Sign up

Export Citation Format

Share Document