Variants in the LRP4 gene are associated with bone mineral density in males and females

2014 ◽  
Author(s):  
N Alonso ◽  
D Kabir ◽  
JF Wilson ◽  
SH Ralston
Keyword(s):  
Bone Mineral Density ◽  
Bone Mineral ◽  
Mineral Density ◽  
Males And Females ◽  
Lrp4 Gene

scholarly journals Computed tomographic analysis of tibiotarsal bone mineral density and content in turkeys as influenced by age and sex

2012 ◽  
Vol 57 (No. 12) ◽  
pp. 573-580 ◽  
Author(s):  
A. Charuta ◽  
R.G. Cooper ◽  
M. Pierzchała ◽  
J.O. Horbańczuk
Keyword(s):  
Computed Tomography ◽  
Bone Mineral Density ◽  
Bone Mineral ◽  
Mineral Content ◽  
Bone Fractures ◽  
Volumetric Bone Mineral Density ◽  
Mineral Density ◽  
Computed Tomographic ◽  
Males And Females ◽  
Tomographic Analysis

Changes in the volumetric bone mineral density (vBMD) and bone mineral content (BMC) of tibiotarsal bones of growing turkeys as affected by birds&rsquo; age, sex, and within-the-bone location, respectively, were determined by computed tomography. The research was performed on 165 heavy-type BIG 6 turkeys reared between weeks (wk) 3&ndash;16 of age. The computed tomography (pQCT) measurement, conducted at 18&nbsp;and 50% of the bone length, comprised a bone fragment which was 0.07 mm thick for the compact and the spongious substance collectively. It should be noted that the diaphyses of the tibiotarsal bones in turkeys (580 mg/cm<sup>3</sup>) had greater vBMD than the proximal metaphyses (300 mg/cm<sup>3</sup>), (P &le; 0.001). BMC was higher in metaphyses for both sexes. Significant differences between the BMC of the metaphyses and the diaphyses were observed in males and females at wk 3 (P &le; 0.01), 6 (P &le; 0.05), and 9 (P &le; 0.001), and at wk 3 (P &le; 0.05) and 12 (P &le; 0.01), respectively. vBMD in the diaphyses gradually attenuated with age for both sexes, from 688 mg/cm<sup>3</sup> (wk 3) to 532 mg/cm<sup>3</sup> (wk 16). vBMD of the metaphyses was constant in females, but in males it achieved maximum values of 350 mg/cm<sup>3 </sup>at wk 6 and 12 and minimum of 260 mg/cm<sup>3 </sup>at wk 9 and 16. Correlations between body weight (BW) and vBMD of the diaphyses were observed in males (r = &ndash;0.85, P &le; 0.001) and females (r = &ndash;0.52, P &le; 0.01). It can be concluded that vBMD loss in diaphyses diminished bone-breaking strength leading in investigated turkeys to deformities and bone fractures.

Factors Influencing Bone Mineral Density Among Adults of Delhi: A Gender Differential

2019 ◽  
Vol 21 (2) ◽  
pp. 199-209 ◽  
Author(s):  
Peteneinuo Rulu ◽  
Meenal Dhall ◽  
Renu Tyagi ◽  
Kshetrimayum Surmala Devi ◽  
Nilupher Feroz ◽  
...  
Keyword(s):  
Bone Mineral Density ◽  
Older Adults ◽  
Bone Mineral ◽  
Fat Body ◽  
Mineral Density ◽  
Cross Sectional ◽  
Body Adiposity Index ◽  
Adiposity Index ◽  
Body Adiposity ◽  
Males And Females

Objective: The aim of the study was to find out the risk factor of bone mineral density (BMD). Methodology: Cross-sectional data were collected on 233 participants (males and females) with age ranging from 20 to 70 years. The subjects were divided into two groups consisting of young adults of 20–45 years and older adults of >45 years. The BMD was calculated by a heel ultrasonic test. Each subject was measured for various adiposity markers like body fat, body mass index, body shape index (BSI), body adiposity index and lifestyle parameters. Results: BSI was found to be higher among older adults in both males and females. The risk of osteoporosis and osteopenia was also seen to be significantly higher among older adults of >45 years ( p < 0.001). Various factors like age ( p < 0.001), milk intake status ( p < 0.05), education ( p < 0.01), occupation ( p < 0.05) and body adiposity index ( p < 0.05) were found to be risks for osteoporosis and osteopenia. Conclusion: In our study, BMD was found to be highly correlated with age, and the risk of osteopenia and osteoporosis increased as age increased. Illiteracy, milk consumption status, homemakers and higher body adiposity were also identified as risk factors for developing osteopenia and osteoporosis.

INTERACTION BETWEEN RATE OF MATURATION AND LIFESTYLE ON BONE MINERAL DENSITY OF MALES AND FEMALES 631

1997 ◽  
Vol 29 (Supplement) ◽  
pp. 111
Author(s):  
H. C.G. Kemper ◽  
J. W.R. Twisk ◽  
W. van Mechelen ◽  
G. B. Post ◽  
F. van Lenthe
Keyword(s):  
Bone Mineral Density ◽  
Bone Mineral ◽  
Mineral Density ◽  
Males And Females

scholarly journals Blood levels related to the Z-score of bone mineral density in young males and females

2015 ◽  
Vol 27 (4) ◽  
pp. 1117-1120 ◽  
Author(s):  
Sun-Hyung Joo ◽  
Min-Tae Kim ◽  
Jae-Hwan Cho ◽  
Hae-Kag Lee ◽  
Jae-Ouk Ahn
Keyword(s):  
Bone Mineral Density ◽  
Bone Mineral ◽  
Blood Levels ◽  
Z Score ◽  
Mineral Density ◽  
Young Males ◽  
Males And Females

Biomechanic and energetic physical activity have differential effects on bone mineral density in 28 years old males and females

1996 ◽  
Vol 6 (S1) ◽  
pp. 106-106
Author(s):  
H. C. G. Kemper ◽  
J. Groothausen ◽  
H. Siemer ◽  
J. W. R. Twisk ◽  
W. van Mechelen ◽  
...  
Keyword(s):  
Physical Activity ◽  
Bone Mineral Density ◽  
Bone Mineral ◽  
Mineral Density ◽  
Differential Effects ◽  
Males And Females

scholarly journals Disparity in bone mineral density of males and females with age

2020 ◽  
Vol 8 (3) ◽  
pp. 429-438
Author(s):  
Nusrat Aziz
Keyword(s):  
Bone Mineral Density ◽  
Bone Mass ◽  
Bone Mineral ◽  
Financial Burden ◽  
Lifestyle Changes ◽  
Control Group ◽  
Age Group ◽  
Mineral Density ◽  
Age Related ◽  
Males And Females

Decline in bone mass with aging leads to osteoporosis and fragility fractures. It has profound effect on the morbidity and health quality of the elderly, creating financial burden on the society. Usually, age related loss in bone mass goes undiagnosed until a fragility fracture occurs. It was observed that the bone mineral density (BMD) was found to be lesser in females compared to males in all age groups. There were significant BMD differences between males and females from age 41 yrs and above, BMD declined with age in both males and females. The maximum decline was observed in age group of 41 yrs -50 yrs compared to the control group of 20 yrs-30 yrs. The decrease in BMD was highly noticeable in females, with osteoporosis from age group 51 yrs-60 yrs. It coincides with peri-menopausal and early after menopause period. In males osteoporosis was not observed until the age of 80yrs, though osteopenia have been observed from 41 yrs onwards. There is a paramount need of awareness about detrimental effects of aging on BMD in order to bring about necessary lifestyle changes and follow therapeutic measures. This enables us to attain higher peak bone mass and maintain higher bone densities.

scholarly journals Relationship between anthropometric/metabolic parameters and bone mineral density in younger adults

2020 ◽  
Vol 79 (OCE2) ◽  
Author(s):  
Roberta Hack-Mendes ◽  
Lorraine Brennan
Keyword(s):  
Bone Mineral Density ◽  
Bone Mineral ◽  
Metabolic Parameters ◽  
Whole Body ◽  
Mineral Density ◽  
Age Related ◽  
Gender And Age ◽  
Males And Females ◽  
The Mean ◽  
The Relationship

AbstractIntroductionOsteoporosis is characterized by low bone mineral density (BMD) and increased susceptibility to low trauma fractures(1).The relationship between osteoporosis risk and general metabolic health parameters is poorly understood. The aim of this study was to investigate the relationship between anthropometric and metabolic parameters with BMD in Adults.Materials and MethodsA total of 214 (100 male and 114 female) healthy adults were recruited. The mean age was 32 ± 10 years for males and 31 ± 11 years for females. BMD was assessed by whole body dual energy X ray- absorptiometry (Dexa scan). Dexa scores were reported as total bone mineral density, T-score and Z-score. Anthropotemetric measures included body weight, height, waist circumference. Basal metabolic rate (BMR) was assessed by indirect calorimetry. Tertiles of BMD were obtained for males and females. Assessment of parameters across BMD tertiles was performed in males and females separately using ANOVA. Relationships between parameters was assessed using Spearman correlation analysis controlling for gender and age where appropriate.ResultsBMI, Weight and BMR increased significantly across the tertiles for both genders. The mean weight, BMI and BMR were significantly increased in the males at the highest tertile of BMD. Positive correlations (adjusted for gender and age) were observed between weight, BMI, BMR and BMD (R2 = 0.404; p = 0.001, R2 = 0.348, p = 0.001; R2 = 0.363; p = 0.001, respectively).ConclusionsOverall, the results confirm the relationships between BMD and BMI and weight in a healthy cohort. Furthermore, it highlights a relationship between BMR and BMD. Targeting improvement in body composition and BMR may be a strategy for the age-related decline in BMD.

Genetic variation in the LRP4 gene influences bone mineral density and hip geometry

Bone ◽  
2011 ◽  
Vol 48 ◽  
pp. S153 ◽  
Author(s):  
E. Piters ◽  
E. Boudin ◽  
F. de Freitas ◽  
T.L. Nielsen ◽  
M. Andersen ◽  
...  
Keyword(s):  
Bone Mineral Density ◽  
Genetic Variation ◽  
Bone Mineral ◽  
Mineral Density ◽  
Hip Geometry ◽  
Lrp4 Gene
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