The activation of RANK/RANKL/OPG system in normal pregnancy and pre-eclampsia

2013 ◽  
Author(s):  
Dorota Darmochwal-Kolarz
Keyword(s):  
Normal Pregnancy

EFFECT OF FEEDING ETHINYLOESTRADIOL FOR VARIOUS PERIODS BEFORE MATING ON REPRODUCTION IN THE HAMSTER

1972 ◽  
Vol 70 (3) ◽  
pp. 582-590
Author(s):  
B. K. Davis ◽  
I. Noske ◽  
M. C. Chang
Keyword(s):  
Single Dose ◽  
Pregnancy Rate ◽  
Fertility Control ◽  
Normal Pregnancy ◽  
Oestrous Cycle ◽  
The Other ◽  
Feeding Schedule ◽  
Crown Rump Length ◽  
Essentially Normal ◽  
Effect Of Feeding

ABSTRACT Ethinyloestradiol (EO) fed for various periods before mating to female hamsters affected the timing of mating and pregnancy rate. Slight effects on ovulation, foetal-crown rump length and resorption may have occurred, but effects on implantation were not apparent among pregnant hamsters. The response observed depended upon the feeding schedule adopted: hamsters fed 2.5 mg EO in a single dose, on day 3 before mating, mated normally but had a significantly lower pregnancy rate; on the other hand, animals fed 2.5 mg EO (0.21 mg/day) over three oestrous cycles, days 14–3 before mating, showed variations in the time of mating but had an essentially normal pregnancy rate; and, a group of hamsters who received the same total amount of EO (0.63 mg/day) over one oestrous cycle, days 6–3 premating, showed untowards effects by the steroid on both the timing of mating and pregnancy rate. The implications of these results are considered in relation to fertility control.

Pathological features of the sequence in pregnant women with delayed fetal growth

2019 ◽  
pp. 50-54
Author(s):  
V.O. Golyanovskiy ◽  
◽  
Ye.O. Didyk ◽  
Keyword(s):  
Pregnant Women ◽  
Intrauterine Growth Restriction ◽  
Normal Development ◽  
Intrauterine Infection ◽  
Normal Pregnancy ◽  
Growth Restriction ◽  
Control Group ◽  
Intrauterine Growth ◽  
Increased Risk ◽  
Infection And Inflammation

Pregnant women with intrauterine growth restriction (IUGR) have an increased risk of adverse perinatal and long-term complications compared with the birth of children with normal body weight. Thus, IUGR is one of the main challenges for the global health system, especially in poor and developing countries. Morpho-functional studies of the placentas help in determining the causes of IUGR, and therefore, timely prevent complications in pregnant women with IUGR. The objective: The purpose of this study is to investigate various morphometric and pathomorphological changes in the placenta, including inflammatory, in cases of IUGR, and to establish a correlation of these results with the etiology and complications for the fetus. Materials and methods. In the current study, 54 placentas of the fetuses with IUGR (the main group) were compared with 50 placentas of the fetuses with normal development (control group). The criteria for the inclusion of IUGR were gestational age more than 30 weeks and all fetuses with a weight less than 10th percentile for this period of pregnancy. The placenta material was studied pathomorphologically with laboratory screening for infection and inflammation. Similarly, the results were determined for placentas of the fetuses with normal development compared to placentas with IUGR. Results. The placenta study showed the presence of calcification in the case of IUGR, as well as in the case of prolonged pregnancy. However, calcification of the placenta in the case of IUGR was more progressive compared with placenta in the normal pregnancy. In addition, the presence of intrauterine infection and inflammation was observed, which could also lead to an adverse outcome for the further progression of pregnancy with IUGR. Conclusion. A comparative macro- and microscopic pathomorphological study of the placentas in the two groups has shown a significant increase in the pathological changes in all the anatomical structures of the fetuses with IUGR. Key words: Intrauterine growth restriction (IUGR), fetal weight, pathomorphological changes of the placenta.

Placental G6Pase and glycogen content in normal pregnancy and small for gestational age pregnancies

2010 ◽  
Vol 95 (Supplement 1) ◽  
pp. Fa22-Fa22
Author(s):  
J. Leonce ◽  
N. Brockton ◽  
A. Burchell ◽  
S. Robinson ◽  
P. Steer ◽  
...  
Keyword(s):  
Gestational Age ◽  
Small For Gestational Age ◽  
Glycogen Content ◽  
Normal Pregnancy

Efficacy of Routine Fetal Ultrasound Screening for Congenital Heart Disease in Normal Pregnancy

Circulation ◽  
1996 ◽  
Vol 94 (1) ◽  
pp. 67-72 ◽  
Author(s):  
E. Buskens ◽  
D.E. Grobbee ◽  
I.M.E. Frohn-Mulder ◽  
P.A. Stewart ◽  
R.E. Juttmann ◽  
...  
Keyword(s):  
Congenital Heart Disease ◽  
Heart Disease ◽  
Congenital Heart ◽  
Normal Pregnancy ◽  
Ultrasound Screening ◽  
Fetal Ultrasound

Flow-Mediated Vasodilatation Is Enhanced in Normal Pregnancy but Reduced in Preeclampsia

Hypertension ◽  
1997 ◽  
Vol 30 (2) ◽  
pp. 247-251 ◽  
Author(s):  
Anna P. Cockell ◽  
Lucilla Poston
Keyword(s):  
Normal Pregnancy

Cell-Derived Microparticles and Complement Activation in Preeclampsia Versus Normal Pregnancy

Placenta ◽  
2007 ◽  
Vol 28 (8-9) ◽  
pp. 928-935 ◽  
Author(s):  
É. Biró ◽  
C.A.R. Lok ◽  
C.E. Hack ◽  
J.A.M. van der Post ◽  
M.C.L. Schaap ◽  
...  
Keyword(s):  
Complement Activation ◽  
Normal Pregnancy

Insulin secretion and insulin sensitivity in normal pregnancy and gestational diabetes mellitus

2003 ◽  
Vol 17 (2) ◽  
pp. 137-142 ◽  
Author(s):  
E. Akbay ◽  
M. B. Tıras ◽  
I. Yetkin ◽  
F. Törüner ◽  
R. Ersoy ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Insulin Secretion ◽  
Insulin Sensitivity ◽  
Gestational Diabetes ◽  
Gestational Diabetes Mellitus ◽  
Normal Pregnancy
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