scholarly journals Anti-dementia acetylcholine esterase inhibitor inhibits osteoclastogenesis

2013 ◽  
Author(s):  
Charles Inderjeeth ◽  
Jiake Xu ◽  
Bay Sie Lim ◽  
Dian Teguh
Keyword(s):  
Acetylcholine Esterase ◽  
Acetylcholine Esterase Inhibitor ◽  
Esterase Inhibitor

Modulation of In Vivo T Cell Activation by an Acetylcholine-Esterase Inhibitor in Patients Chronically Infected with HIV

2007 ◽  
Vol 123 ◽  
pp. S46
Author(s):  
Carlos Cantu-Brito ◽  
Sergio Ivan Valdes-Ferrer ◽  
Jose Crispin ◽  
Francisco Belaunzaran ◽  
Maria Ines Vargas Rojas ◽  
...  
Keyword(s):  
T Cell ◽  
T Cell Activation ◽  
Cell Activation ◽  
Acetylcholine Esterase ◽  
Acetylcholine Esterase Inhibitor ◽  
Esterase Inhibitor

scholarly journals Regioselective Asymmetric Alkynylation of N–Alkyl Pyridiniums

2021 ◽  
Author(s):  
Thiago A. Grigolo ◽  
Ariana R. Subhit ◽  
Joel Smith
Keyword(s):  
Asymmetric Synthesis ◽  
Acetylcholine Esterase ◽  
Reaction Conditions ◽  
Asymmetric Addition ◽  
Simple Reaction ◽  
Stereochemical Control ◽  
Acetylcholine Esterase Inhibitor ◽  
Esterase Inhibitor

Disclosed in this communication is a novel asymmetric addition of alkynyl nucleophiles to <i>N</i>-alkyl pyridinium electrophiles. The coupling is effected under mild and simple reaction conditions, affording dihydropyridine products with complete regiochemical and stereochemical control. In addition to several manipulations of the dihyropyridine products, the utility of this transformation is demonstrated through a concise, dearomative, and asymmetric synthesis of (+)-lupinine, a natural acetylcholine esterase inhibitor.

scholarly journals Organophosphate acetylcholine esterase inhibitor poisoning from a home-made shampoo

2011 ◽  
Vol 4 (3) ◽  
pp. 433 ◽  
Author(s):  
Arnon Broides ◽  
Matitiahu Lifshitz ◽  
Yair Sadaka ◽  
RaffiLev Tzion
Keyword(s):  
Acetylcholine Esterase ◽  
Acetylcholine Esterase Inhibitor ◽  
Esterase Inhibitor

scholarly journals THE EFFECT OF DURATION OF ACETYLCHOLINE-ESTERASE INHIBITOR ON MMSE, CDT AND BARTHEL INDEX SCORING ON PATIENTS WITH VASCULAR DEMENSIA

2021 ◽  
Vol 7 (2) ◽  
pp. 104-108
Author(s):  
Sri Budhi Rianawati ◽  
Ria Damayanti ◽  
Harun Al Rasyid ◽  
Nyoman Artha Megayasa
Keyword(s):  
Cognitive Function ◽  
Vascular Dementia ◽  
Barthel Index ◽  
Acetylcholine Esterase ◽  
Clock Drawing Test ◽  
Dementia Patients ◽  
The Many ◽  
State Examination ◽  
Acetylcholine Esterase Inhibitor ◽  
Esterase Inhibitor

Background: Vascular dementia is a cognitive decline with functional deterioration caused by cerebrovascular disease. It is the second leading cause of dementia. A number of screening questionnaires and models have been developed to help in assessing cognitive function and activity daily living (ADL) in patients with dementia. Mini Mental State Examination (MMSE), Clock Drawing Test (CDT) and Barthel Index are instruments to evaluate cognitive function and ADL of vascular dementia patients. Objective: To determine the role of achetylcholine-esterase inhibitor therapy on cognitive function and ADL in patients with vascular dementia in Saiful Anwar General Hospital. Methods: This study is an analytical study assessing the improvement of cognitive function and ADL of patients with vascular dementia after administration of acethylcholine-esterase inhibitor by assessing the MMSE, CDT and Barthel Index scoring in 1, 3, 6 and 12 month period consecutively. Results: From 15 study subjects, individuals who have been given treatment for 12 months consecutively have the highest increase in MMSE and CDT whilst for Barthel Index has shown highest improvement in one month period. Conclusion: The administration of acetylcholine-esterase inhibitor drugs has the potential to improve and maintain cognitive function and improve ADL. The limited number of study subjects and the many confounding factors that we did not evaluate were the drawbacks of this study. The results of this study cannot be generalized to all patients with vascular dementia and only apply to 15 patients who were the subjects of this study.

Sign in / Sign up

Export Citation Format

Share Document