Sexual precocity in a boy due to hypersecretion of LH and prolactin by a pituitary adenoma

1983 ◽  
Vol 102 (2) ◽  
pp. 167-172 ◽  
Author(s):  
M. Faggiano ◽  
T. Criscuolo ◽  
L. Perrone ◽  
C. Quarto ◽  
A. A. Sinisi

Abstract. The paper reports on precocious puberty and galactorrhoea in a 4 8/12 year old boy. Roentgenograms of the skull showed slight lateral bulging of sella floor and pneumoencephalography indicated a pituitary adenoma with a suprasellar extension. Pre-operative study of anterior pituitary function was normal except for increased values of LH (900 mIU/ml), testosterone (2000 ng/ml) and prolactin (215 ng/ml). After removal of a chromophobe pituitary adenoma by transfrontal surgery the galactorrhoea disappeared within 10 days. Post-operative endocrine evaluation showed immediate normalization of LH, testosterone and prolactin values.

2019 ◽  
Vol 17 (4) ◽  
pp. 382-388
Author(s):  
Eui Hyun Kim ◽  
Ju Hyung Moon ◽  
Sun Ho Kim

Abstract BACKGROUND During transsphenoidal surgery (TSS) for a pituitary adenoma with a large suprasellar extension, cerebrospinal fluid (CSF) leakage commonly develops from a defect in the arachnoid recess or the arachnoid membrane. OBJECTIVE To evaluate the usefulness of a newly developed clipping technique for the repair of intraoperative CSF leakage. METHODS Between September 2012 and November 2016, 698 patients with pituitary adenoma were operated on with TSS. Intraoperative CSF leakage was encountered in 301 patients (43.1%). The clipping technique was used to repair CSF leakage in 144 patients: from the arachnoid recess in 100 patients and from the arachnoid membrane in 44 patients. The clipping technique used titanium clips and a newly designed clip applier. We evaluated anterior pituitary function of the patients whose CSF leakage was closed by clipping, and compared this with function in another patient group treated with different repair techniques. RESULTS We successfully applied clip technique in 140 out of 144 patients. This clipping technique was faster and easier for repairing CSF leakage than our previously published suture technique. In our early series, 4 patients developed unexpected CSF rhinorrhea after TSS. We found no difference in anterior pituitary function between a clipping group and others. Although titanium clip was identified on postoperative MRI, its metallic scattered artifact was very minimal and did not hinder the detection of possible remnant and recurrent tumors. CONCLUSION This clipping technique is a very simple and reliable method for repairing intraoperative CSF leakage when properly applied with caution.


1995 ◽  
Vol 42 (3) ◽  
pp. 421-427 ◽  
Author(s):  
ATSUSHI TOMINAGA ◽  
TOHRU UOZUMI ◽  
KAZUNORI ARITA ◽  
KAORU KURISU ◽  
TAKASHI YANO ◽  
...  

2007 ◽  
Vol 149 (6) ◽  
pp. 557-565 ◽  
Author(s):  
A. Yoshino ◽  
Y. Katayama ◽  
T. Watanabe ◽  
A. Ogino ◽  
T. Ohta ◽  
...  

1989 ◽  
Vol 120 (3_Suppl) ◽  
pp. S49-S50 ◽  
Author(s):  
J. SCHOPOHL ◽  
G. MEHLTRETTER ◽  
M. LOSA ◽  
G. K. STALLA ◽  
O. A. MÜLLER ◽  
...  

Contraception ◽  
1992 ◽  
Vol 46 (2) ◽  
pp. 175-179
Author(s):  
Weinyen Lu ◽  
Weiming She ◽  
Zhenyu Nan ◽  
Chungming Hsieh

2012 ◽  
Vol 97 (1) ◽  
pp. E121-E128 ◽  
Author(s):  
Marie-Hélène Quentien ◽  
Brigitte Delemer ◽  
Dimitris T. Papadimitriou ◽  
Pierre-François Souchon ◽  
Roland Jaussaud ◽  
...  

1977 ◽  
Vol 17pt2 (3) ◽  
pp. 219-225
Author(s):  
SHIGEJIRO MATSUMURA ◽  
SHINTARO MORI ◽  
HISANORI YOSHIMOTO ◽  
MASAHIRO OHTA ◽  
HIROMICHI HIBINO ◽  
...  

Author(s):  
P. Franchimont ◽  
J. J. Legros ◽  
B. Deconinck ◽  
P. Demeyts ◽  
M. Goulart ◽  
...  

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