METABOLISM OF 17β-OESTRADIOL-17α-3H BY THE PREVIABLE HUMAN FOETUS AT MIDTERM

1970 ◽  
Vol 63 (1) ◽  
pp. 39-49 ◽  
Author(s):  
G. Benagiano ◽  
S. Mancuso ◽  
B. de la Torre ◽  
E. Diczfalusy
Keyword(s):  
The Other ◽  
Significant Part ◽  
Isotopic Ratios ◽  
Human Foetus ◽  
Homogeneous Form ◽  
Other Hand ◽  
Foetal Liver ◽  
Different Sources ◽  
Direct Hydroxylation

ABSTRACT One female and one male foetus were perfused at midpregnancy with 17β-oestradiol-16-14C,17α-3H and metabolites were isolated in a radiochemically homogeneous form from the perfusates and various foetal tissues. The 3H/14C ratio of the perfused material was 60.2. Unconjugated and conjugated 17β-oestradiol and oestrone were isolated from all tissues studied. The 3H/14C ratio of the oestradiol isolated from all tissues, except the liver, agreed with the perfused one. The oestrone isolated from different sources did not contain any 3H-label. Unconjugated oestriol and conjugated oestriol, 16-epi-oestriol, 16α-hydroxy-oestrone, 16-oxo-oestradiol and 15α-hydroxy-oestradiol were isolated from the extracts of the livers. No 3H-label was present in 16α-hydroxy-oestrone, and only traces, if any, in 16-oxo-oestradiol. On the other hand, the isotopic ratios of 16-epi-oestriol, oestriol and 15α-hydroxy-oestradiol were between 1.5 and 5.0. It is concluded that a small but significant part of the oestriol, 16-epi-oestriol and 15α-hydroxy-oestradiol synthesized by the foetal liver is formed via a direct hydroxylation of oestradiol.

ACETATE AND CHOLESTEROL METABOLISM IN THE HUMAN FOETO-PLACENTAL UNIT AT MIDGESTATION.

1970 ◽  
Vol 63 (1) ◽  
pp. 91-104 ◽  
Author(s):  
G. Telegdy ◽  
J. W. Weeks ◽  
U. Lerner ◽  
G. Stakemann ◽  
E. Diczfalusy
Keyword(s):  
Human Placenta ◽  
Metabolic Pathway ◽  
Sodium Acetate ◽  
Cholesterol Metabolism ◽  
The Other ◽  
Human Foetus ◽  
Homogeneous Form ◽  
Other Hand ◽  
Maternal Side

ABSTRACT As the first part of a series of investigations on acetate and cholesterol metabolism, the conversion of acetate to cholesterol was studied in the various compartments of the midgestation foeto-placental unit in perfusion experiments carried out for 90 min at 35–36°C. Following their removal at laparotomy two complete foeto-placental units were perfused each with 5.0 mCi of uniformly labelled sodium acetate-14C + 5.0 mCi of cholesterol-7α-3H. The study was completed by the separate perfusion of two isolated midgestation foetuses and two midgestation placentas. The doses administered in each of these four last experiments were 2.5 mCi of 14C-labelled acetate and 2.5 mCi of 3H-labelled cholesterol. Cholesterol was isolated in a radiochemically homogeneous form from each of the tissues studied. The cholesterol isolated from the placentas, placental perfusates and from the blood bathing the placenta from the maternal side (»maternal perfusates«) contained exclusively 3H-label. On the other hand, the cholesterol isolated from all foetal livers, adrenals, testicles, 3 of 4 residual foetal tissues and 1 out of 4 foetal perfusates also contained significant quantities of 14C-label. It is concluded, that the midgestation human placenta is not capable of synthesizing cholesterol from acetate, but that the conversion of acetate to cholesterol is a quantitatively significant metabolic pathway in the human foetus at midgestation.

scholarly journals Microbiological Contamination of Honeys from Different Sources in Turkey

2018 ◽  
Vol 62 (1) ◽  
pp. 89-96
Author(s):  
Ayse E. Borum ◽  
Mesut E. Gunes
Keyword(s):  
Clostridium Botulinum ◽  
Hand Washing ◽  
The Other ◽  
Paenibacillus Larvae ◽  
Honey Sample ◽  
Microbiological Contamination ◽  
Other Hand ◽  
Pure Cultures ◽  
Different Sources ◽  
Microbiological Properties

Abstract Honey samples obtained by beekeepers taken from thirty-five different apiaries in Turkey’s region of Marmara were investigated for the presence of microorganism. Each honey sample was examined for the number of total aerobic mesofilic bacteria, coliforms, moulds and yeasts and the presence of Salmonella spp., Clostridium botulinum, along with other aerobic bacteriae such as Paenibacillus larvae and Melissococcus plutonius. In total, fifty-four honey samples of different botanical origins including unifloral (Umbelliferae, Leguminosae, Trifolium, Onobrychis), multifloral and chestnut were evaluated in the means of microbiological properties. Microorganisms were isolated in twenty-eight samples (60.86%) of pure cultures and eighteen samples (39.13%) of mixed cultures. On the other hand, no microorganisms were isolated in eight samples. Bacillus spp, Corynebacterium spp., Streptococcus spp., Staphylococcus spp. C. albicans and Penicillium spp. were isolated and identified in other honey samples. The bacteria counts were 4×102 - 1.4×103 cfu/g for aerobic mesofilic bacteria and 1-185 cfu/g for the fungi. The application of sanitary practices (hand washing, avoidance of sneezing or coughing, etc.) may be effective in controlling contamination by microorganisms. On the other hand, air, equipment and dust may be contributing causes of microbiological contamination. Therefore it is important to take precautions in order to avoid such contamination, even though such factors are often difficult to control.

Vergilius Astronomiae Ignarus?

Mnemosyne ◽  
2019 ◽  
Vol 72 (4) ◽  
pp. 621-646
Author(s):  
Frederik A. Bakker
Keyword(s):  
The Other ◽  
Other Hand ◽  
The Subject ◽  
Combine Information ◽  
Different Sources

AbstractBoth in antiquity and today Virgil is sometimes accused of ignorance in astronomy. This paper argues that, on the contrary, Virgil’s treatment of astronomical topics in Georgics 1.231-258 shows that he was quite familiar with the subject, and was able (when he wished to) to combine information from different sources (Aratus, Eratosthenes and other, unidentified ones) into a sensible and harmonious whole. On the other hand, the omission of essential steps between the various parts of his account, and the deliberate confusion of science and myth show us that his ultimate aim was not to inform the ignorant but to amuse and surprise readers who were just as familiar with astronomy as Virgil himself.

scholarly journals Ethnic Russian Minority in Estonia

2016 ◽  
Vol 18 (2) ◽  
pp. 153-164 ◽  
Author(s):  
Agata Włodarska-Frykowska
Keyword(s):  
Russian Federation ◽  
Language Education ◽  
The State ◽  
The Other ◽  
Significant Part ◽  
Political Life ◽  
Proficiency Level ◽  
Other Hand ◽  
The Russian Federation

The article examines the position of Russians in Estonia and their relation with ethnic Estonians. The author analyzes models of the society integration introduced by Tallinn after 1991. The results raise questions regarding language education in Estonia, the proficiency level of Estonian is getting widely known by Russians, but on the other hand, there is still a significant part of the population that cannot communicate in Estonian. Those who have a good command of Estonian tend to be better integrated and to coexist with both Estonians and Russians. Russians living in Estonia are supposed to be equally involved in social and political life of the state. The potential of all residents has to be effectively and considerably used, especially when the number of population is decreasing. The position of Russians in Estonia is a major domestic and bilateral issue in the relations with the Russian Federation.

scholarly journals Compare of Food Habit and Nutritional Status of Rural Male and Female

2021 ◽  
Vol 8 (10) ◽  
pp. 556-572
Author(s):  
Redwan Rahman ◽  
Mahfuza Khanom Sheema
Keyword(s):  
Nutritional Status ◽  
Eating Habits ◽  
Food Habit ◽  
Lower Class ◽  
The Other ◽  
Male And Female ◽  
Other Hand ◽  
The People ◽  
Different Sources ◽  
North Western

ABSTRACT There is a big difference between male and female in the rural environment of Bangladesh and the aim of this eating habits and nutritional status. The study was conducted through 384 respondents from 9 villages in Ishwardi, Pabna; a north-western district of Bangladesh. The research has done on the food habits of the middle and lower class people of the villages. And some informations are collected from the different sources. In the research 73.44% of male earn more than 24 thousand BDT per month when only 43.32% female are earning more than 24 thousand BDT. Most of the female are housewives and male are service holder. 44.79% male  are service holder on the other hand 4.69% female are service holder. Rice is the main food for Bangladesh. So, most of the people have rice on daily three times. 37.80% of female and 66.98% of male are having rice. Ruti is the second priority food, female take this food 0.56% and male take 7.55% for 2 days. 63.33% female take egg, on the other hand 58.07% male take egg per week.  3.2% female her meal last of all and 1.5% female take it first of all. On the other hand 6.25% male take their meal first of all and 3.39% male take their meal last of all. Most of the female are normal having BMI 89.06% on the other hand male are overweight 78.18%. In the light of the study the eating habits of male and female in Bangladesh have improved but it has not yet affected everyone.          

scholarly journals SEMANTIC MODEL “DILIGENT” IN THE BALTIC-FINNIC LANGUAGES

2020 ◽  
Vol 14 (2) ◽  
pp. 214-221
Author(s):  
Irma Ivanovna Mullonen ◽  
Tatjana Vladimirovna Pashkova
Keyword(s):  
Hard Work ◽  
The Other ◽  
Significant Part ◽  
Semantic Model ◽  
Literary Language ◽  
Slavic Linguistics ◽  
Other Hand ◽  
The One ◽  
The Baltic ◽  
Semantic Evolution

The article presents a semantic-motivational analysis of twenty Baltic-Finnic dialect and literary language words used to nominate a hard-working person. The source of the material was the dialect dictionaries of individual Baltic-Finnish languages and their file cabinets. The data of etymological dictionaries are also involved. The undertaken research was carried out in line with ethnolinguistics, which is developing successfully in Slavic linguistics, despite the fact that practically no such studies were conducted on the material of the Baltic-Finnish languages. Involving as a comparison the corresponding results according to the Russian dialects showed that the linguistic image of the hardworking is characterized by certain universals in the motivation for naming. However, the Baltic-Finnish units differ in their specificity. The nominations of hardworking people are secondary in them and go back to the names, on the one hand, of dynamic qualities ‘quick, brisk, energetic’, on the other hand, spiritual characteristics (‘enthusiastic, passionate, greedy’) that turn out to be etymologically closely related. It was revealed that they correlate with the basics marking fast, sharp, intense movement - from walking to a blow or a gust of wind. At the same time, a significant part of the verbs of this series can be confidently qualified as having a descriptive, onomatopoeic nature, which is also inherited by the names of hard workers. The revealed regularity of semantic evolution (‘quick abrupt movement’ → ‘fast, energetic, passionate’ → ‘hardworking’) is important for establishing the etymological sources of words that represent the idea of hard work, as it defines a certain algorithm for such a search. Now the lexemes representing the established semantic paradigm are actually divorced according to different etymological articles and the connection between them is most often not indicated in any way.

scholarly journals Beggars, scammers, discriminated against by the whole of Europe: Romania’s Roma in Finnish tabloids, 2008-2011

2012 ◽  
Vol 4 (2) ◽  
pp. 87-109 ◽  
Author(s):  
Kari Alenius
Keyword(s):  
The Other ◽  
Significant Part ◽  
Radical Right ◽  
Recent Case ◽  
Short Term ◽  
Host Countries ◽  
Other Hand ◽  
The Stability ◽  
Critical Perspectives

The unrestricted movement of EU citizens from one country to another has been one of the fundamental principles of the Union. On the other hand, this issue has also attracted criticism, particularly from the radical right and so-called populist parties, or the supporters of these movements. Part of the population of Europe regards immigration and the unrestricted movement of people as a threat to the stability and prosperity of their own society. Through these critical perspectives, permanent immigration is viewed as a larger problem, as its effects on the host countries are more permanent than in the case of temporary residence. Through the same perspectives, the short-term but uncontrolled stay of foreigners is often linked to crime. This study concentrates on what kind of image a significant part of the Finnish media has given of a recent case of the foreigners that have attracted large attention in the country.

“The Law of Any Lasting Development”: Yu. F. Samarin – the Founder of the “Russian School”

2019 ◽  
Vol 54 ◽  
pp. 13-21
Author(s):  
Alexander E. Kotov
Keyword(s):  
Real Life ◽  
Similar Type ◽  
The Other ◽  
Significant Part ◽  
Political Struggle ◽  
Russian School ◽  
Russian People ◽  
Other Hand ◽  
The Law ◽  
The Baltic

Yu.F. Samarin was the true founder of the “Russian school” of the 1860s – 1890s and in a way of the whole of Russian political modernism. His intrinsical “German” rational consistency deterred him from opposition, determined his peculiar tactics of political struggle and the no less peculiar style of polemics. One of the most striking examples of the latter is his correspondence with baroness von Raden, illustrating the dialogue between not only supporters of different views on the Russian question, but also of followers of the similar type of religion. While not being a Protestant, Samarin still was bent to exactly Protestantism. At the same time, the Protestant tendencies in Samarin’s religiousness were dictated precisely by his conservatism: “formally correct syllogism” for him always required testing by “real life”, and a significant part of conservative contemporaries turned out to be latent revolutionaries. The main object of his criticism was the birth privileges of the Baltic Germans, who served the emperor, but not the Russian people, and who with the unification of Germany received another center of attraction. Samarin was the person, who more fully than many of his contemporaries studied the question of the connection between the estate and the national principles. His views were most succinctly expressed in his polemics with the conservative-aristocratic “Vest” journal. Yury Fedorovich strongly denied the possibility of building a state on the basis of supranational aristocratic elite. On the other hand, his anti-aristocratic pathos logically led Samarin to a certain tolerance towards the serving bureaucracy. Some of Samarin’s theses in the early 1860s were accepted by M.N. Katkov.

The Physical Activity Behaviors Outside School and BMI in Adolescents

2010 ◽  
Vol 7 (6) ◽  
pp. 754-760 ◽  
Author(s):  
Jorge Mota ◽  
José Carlos Ribeiro ◽  
Joana Carvalho ◽  
Maria Paula Santos
Keyword(s):  
Physical Activity ◽  
Active Transport ◽  
The Other ◽  
Other Hand ◽  
Different Sources ◽  
Portuguese Adolescents ◽  
Out Of School

Background:The aim of this study is to investigate the associations between active transport (AT), nonorganized out of school physical activity (NOPA) and organized out of school PA (OPA) with BMI in Portuguese adolescents.Methods:The sample comprised 1121 adolescents age 13 to 17 years-old, which were assigned to 1 of 4 PA groups according to the sum of participation in different physical activity behaviors outside of school [AT, OPA, and NOPA].Results:In boys but not in girls, BMI was lower as the participation in more PA behaviors outside school increased. For those who only carry out 1 PA behavior, AT was the most common behavior (boys = 48.9%; girls = 55.1%). On the other hand, NOPA was the most common behavior for those engaged in 2 types of PA (girls = 51.6%; boys = 46%). For those that carried out all the PA behaviors outside school OPA was the most common choice in both girls (59.5%) and boys (54%). AT, NOPA and OPA are different sources of PA outside school that accrued in different ways to the increased level of PA.Conclusions:In boys but not in girls, BMI was lower as the participation in more PA behaviors outside school increased.

Town and Steppe in Ottoman Syria: Hostility, Exploitation and Cooperation in the Late Seventeenth and Eighteenth Centuries

Der Islam ◽  
2015 ◽  
Vol 92 (1) ◽  
Author(s):  
James A. Reilly
Keyword(s):  
Nineteenth Century ◽  
Eighteenth Century ◽  
Urban Life ◽  
The Other ◽  
Urban Centers ◽  
Other Hand ◽  
Literary Sources ◽  
The One ◽  
Urban People ◽  
Different Sources

AbstractLate-seventeenth- and eighteenth-century sources from the Homs and Hama region in Ottoman Syria present contrasting portrayals of Bedouins. Taken together, these sources offer conflicting perspectives with respect to relationships between peoples of the towns and the steppe. On the one hand, literary sources typically portray Bedouins as antitheses of urban life, as savage wanderers who lived outside the norms of propriety and who collectively posed a threat to the wellbeing and property of settled people and of travelers. But on the other hand, legal sources portray Bedouins variously as targets of exploitation or taxation by urban-based governments; or as partners with urban people in contractual undertakings; or as imperial subjects who, like any others, would seek justice in the urban Sharīʿa courts. The article explores these differing characterizations, and seeks to explain the multifarious realities that different sources convey. It concludes by suggesting that relationships between town and steppe were on their way to becoming more institutionalized in the last years of the eighteenth century. This development foreshadowed documented nineteenth-century trends in which urban civil norms and institutions became noticeable in the lives of Bedouins who lived in proximity to towns and urban centers.

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