STEROID HORMONE PRODUCTION FOLLOWING ADRENAL STIMULATION IN THE RHESUS MONKEY

1968 ◽  
Vol 58 (4) ◽  
pp. 637-642
Author(s):  
M. T. Scurry ◽  
J. Bruton
Keyword(s):  
Growth Hormone ◽  
Rhesus Monkey ◽  
Steroid Hormone ◽  
Thyroid Stimulating Hormone ◽  
Adrenal Androgen ◽  
Hormone Production ◽  
Melanocyte Stimulating Hormone ◽  
Adrenal Response ◽  
Stimulation Of ◽  
Stimulating Hormone

ABSTRACT The adrenal response to the infusion of various corticotrophin (ACTH) preparations and other hormones in the orchiectomized rhesus monkey has been measured by the excretion of 17-hydroxycorticosteroids, 17-ketosteroids, and 11-deoxy-17-ketosteroids. No difference was found in the response to genuine or synthetic ACTH. A response was demonstrated with 0.8 U or more of ACTH per 24 hours. No adrenal response was observed to infusions of various gonadotrophins, growth hormone, prolactin, α-melanocyte stimulating hormone, and thyroid stimulating hormone. Angiotensin selectively stimulated aldosterone excretion. No evidence was found for any selective stimulation of adrenal androgen production.

Effects of trifluoperazine on rat prolactin, growth hormone, thyroid stimulating hormone and adrenocorticotrophin secretion in vitro

1983 ◽  
Vol 103 (4) ◽  
pp. 492-496 ◽  
Author(s):  
Ruth C. Powell ◽  
Mark Daniels ◽  
Graham K. Innes ◽  
Michael J. Ashby ◽  
Keith Mashiter
Keyword(s):  
Growth Hormone ◽  
Primary Cultures ◽  
Hormone Secretion ◽  
Thyroid Stimulating Hormone ◽  
Pituitary Hormone ◽  
Gh Secretion ◽  
Tsh Secretion ◽  
Stimulation Of ◽  
Stimulating Hormone

Abstract. We have studied the effects of trifluoperazine, a proposed inhibitor of calmodulin directed cellular function, on adrenocorticotrophic hormone (ACTH), thyroid stimulating hormone (TSH), prolactin (Prl) and growth hormone (GH) secretion from primary cultures of rat adenohypophyseal cells. 5 × 10−6 m and 10−5 m trifluoperazine caused a significant (P < 0.005) reversible dose-related decrease in basal Prl secretion but was less effective on basal GH secretion, significant reversible inhibition (P< 0.005) occurring only with 10−5 m. Trifluoperazine did not consistently alter basal ACTH or TSH secretion but did inhibit 10−2 m theophylline stimulation of ACTH, Prl and GH secretion and 1.5 × 10−7 m TRH stimulation of TSH and Prl secretion. Paradoxically 10−5 m trifluoperazine enhanced theophylline stimulation of TSH secretion. Our results show trifluoperazine to have differential effects on Prl, GH, ACTH and TSH secretion, which are consistent with the known calcium dependence of pituitary hormone secretion and may suggest a role for calmodulin in this process.

scholarly journals Regulation of thyroid and pituitary function by bacterial lipopolysaccharide

2010 ◽  
Vol 56 (2) ◽  
pp. 179-186 ◽  
Author(s):  
N.V. Yaglova ◽  
T.T. Berezov
Keyword(s):  
Thyroid Hormone ◽  
Thyroid Gland ◽  
Binding Capacity ◽  
Hormone Secretion ◽  
Thyroid Stimulating Hormone ◽  
Bacterial Lipopolysaccharide ◽  
Hormone Production ◽  
Thyroid Cells ◽  
Stimulation Of ◽  
Stimulating Hormone

Activation of toll-like receptors-4 by bacterial lipopolysaccharide downregulates pituitary and thyroid function. Besides decrease of thyroid-stimulating hormone secretion lipopolysaccharide affects secretion in follicular thyroid cells directly. The endotoxin partialy activates and inhibits different phases of follicular thyrocytes' secretion. Lipopolysaccharide enhances thyroglobulin synthesis and exocytosis into follicular lumen and supresses its resorbtion.It results in sharp drop of blood thyroxine concentration without decrease of deiodinases-mediated thiroxine to triiodothyronine conversion. Stimulation of the lipopolysaccharide-pretreated thyroid gland with thyroid-stimulating hormone increases resorbtion of thyroglobulin and thyroid hormone production. Combined stimulation of the thyroid gland increases protein bound thyroxine and triiodothyronine serum concentration unlike only TSH stimulation resulting in increase of free thyroid hormone levels. It also prooves that binding capacity of thyroid hormone serum transport proteins during nonthyroidal illness syndrome remains normal.

Effect of 3,5-diiodo-L-thyronine on thyroid stimulating hormone and growth hormone serum levels in hypothyroid rats

Life Sciences ◽  
1998 ◽  
Vol 62 (26) ◽  
pp. 2369-2377 ◽  
Author(s):  
Maria Moreno ◽  
Assunta Lombardi ◽  
Pietro Lombardi ◽  
Fernando Goglia ◽  
Antonia Lanni
Keyword(s):  
Growth Hormone ◽  
Serum Levels ◽  
Thyroid Stimulating Hormone ◽  
Stimulating Hormone

Stimulation of thyroid-stimulating hormone (TSH) receptor antibody production following painless thyroiditis

2004 ◽  
Vol 60 (1) ◽  
pp. 49-53 ◽  
Author(s):  
Makoto Iitaka ◽  
Nils G. Morgenthaler ◽  
Naoko Momotani ◽  
Atsuo Nagata ◽  
Naofumi Ishikawa ◽  
...  
Keyword(s):  
Antibody Production ◽  
Thyroid Stimulating Hormone ◽  
Tsh Receptor ◽  
Receptor Antibody ◽  
Tsh Receptor Antibody ◽  
Painless Thyroiditis ◽  
Stimulation Of ◽  
Stimulating Hormone

Pituitary-bone connection in skeletal regulation

2016 ◽  
Vol 28 (2) ◽  
Author(s):  
Mone Zaidi ◽  
Li Sun ◽  
Peng Liu ◽  
Terry F. Davies ◽  
Maria New ◽  
...  
Keyword(s):  
Growth Hormone ◽  
Follicle Stimulating Hormone ◽  
Pituitary Hormones ◽  
Thyroid Stimulating Hormone ◽  
Bone Diseases ◽  
Adrenocorticotrophic Hormone ◽  
Metabolic Bone Diseases ◽  
Metabolic Bone ◽  
Limited Function ◽  
Stimulating Hormone

AbstractPituitary hormones have traditionally been thought to exert specific, but limited function on target tissues. More recently, the discovery of these hormones and their receptors in organs such as the skeleton suggests that pituitary hormones have more ubiquitous functions. Here, we discuss the interaction of growth hormone (GH), follicle stimulating hormone (FSH), thyroid stimulating hormone (TSH), adrenocorticotrophic hormone (ACTH), prolactin, oxytocin and arginine vasopressin (AVP) with bone. The direct skeletal action of pituitary hormones therefore provides new insights and therapeutic opportunities for metabolic bone diseases, prominently osteoporosis.

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