EFFECT OF PREGNANCY ON THE RABBIT URINARY BLADDER AND URETER.

1968 ◽  
Vol 57 (3) ◽  
pp. 427-440
Author(s):  
Finn Rasmussen
Keyword(s):  
Urinary Bladder ◽  
Connective Tissue ◽  
Marked Reduction ◽  
Significant Rise ◽  
Hormone Production ◽  
Bladder Tissue ◽  
Acid Mucopolysaccharides ◽  
Tissue Changes ◽  
Healing Wounds ◽  
Rabbit Urinary Bladder

ABSTRACT The connective tissue changes in the intact urinary bladder and ureteral tissues, and in healing urinary bladder wounds, were studied in pregnant and non-pregnant female rabbits. Pregnancy caused a significant rise in ureteral water content, but no significant alterations in intact bladder tissue. In the healing wounds, a marked reduction in the content of acid mucopolysaccharides and in the uptake of radiosulphate was observed from the seventh day after operation. At this time, the production of relaxin is known to increase rapidly. A possible relation between the lowered content of acid mucopolysaccharides and hormone production during pregnancy, is discussed.

CONNECTIVE TISSUE CHANGES IN THE RABBIT URINARY BLADDER AND URETER DURING PREGNANCY

1972 ◽  
Vol 69 (4) ◽  
pp. 769-774
Author(s):  
Finn Rasmussen
Keyword(s):  
Urinary Bladder ◽  
Connective Tissue ◽  
Water Content ◽  
Uronic Acid ◽  
Morphological Changes ◽  
Hormonal Influence ◽  
Tissue Changes ◽  
Rabbit Urinary Bladder ◽  
Acid Glycosaminoglycan

ABSTRACT The urinary bladder and ureters from 8 normal and 40 pregnant rabbits were studied histologically, and also by acid glycosaminoglycan analysis. No morphological changes could be demonstrated. In the later stages of pregnancy the water content was found to be lowered, and a decrease in hexosamine and uronic acid contents in bladder walls was demonstrated on the 28th day of pregnancy. It is believed that the changes are due to a hormonal influence.

THE EFFECT OF OESTROGENS ON THE HEALING OF URINARY BLADDER WOUNDS.

1967 ◽  
Vol 55 (2) ◽  
pp. 346-360 ◽  
Author(s):  
Finn Rasmussen
Keyword(s):  
Urinary Bladder ◽  
Bladder Wall ◽  
Collagen Production ◽  
Treated Male ◽  
Acid Mucopolysaccharides ◽  
Healing Wounds

ABSTRACT The healing of linear wounds in the urinary bladder was studied in control and oestrogen-treated male rabbits. Oestradiol monobenzoate increased the content of acid mucopolysaccharides in the bladder wall, decreased the synthesis of acid mucopolysaccharides in the healing wounds. and had no effect on collagen production.

Comparative evaluation of antioxidant reactivity within obstructed and control rabbit urinary bladder tissue using FRAP and CUPRAC assays

2008 ◽  
Vol 323 (1-2) ◽  
pp. 139-142 ◽  
Author(s):  
Holly Bean ◽  
Florian Radu ◽  
Elise De ◽  
Catherine Schuler ◽  
Robert E. Leggett ◽  
...  
Keyword(s):  
Urinary Bladder ◽  
Comparative Evaluation ◽  
Bladder Tissue ◽  
Control Rabbit ◽  
And Control ◽  
Rabbit Urinary Bladder

EFFECT OF ANDROGENS AND ANABOLIC STEROIDS ON RABBIT URINARY BLADDER AND URETER

1968 ◽  
Vol 57 (3) ◽  
pp. 414-426 ◽  
Author(s):  
Finn Rasmussen
Keyword(s):  
Urinary Bladder ◽  
Testosterone Propionate ◽  
Morphological Changes ◽  
Anabolic Steroids ◽  
Experimental Period ◽  
Hormone Treatment ◽  
Collagen Concentration ◽  
Healing Wounds ◽  
Growth Promoting ◽  
Rabbit Urinary Bladder

ABSTRACT The effect of testosterone propionate and methandrostenolone on the connective tissue components in intact bladder, ureter, and healing linear urinary bladder wounds was studied in male albino rabbits. No morphological changes due to hormone treatment was observed. Treatment with testosterone propionate caused a decrease in the content of water and acid mucopolysaccharides during most of the experimental period, which lasted for 28 days after the production of wounds, and decreased the collagen concentration 28 days after operation. Methandrostenolone showed a growth-promoting action as well as a dubious depressant effect on the water content in the healing wounds, but was without influence on the collagen and acid mucopolysaccharide contents.

THE HEXOSAMINE CONTENT OF THE ORBIT IN RELATION TO ANTI-THYROTROPHIN ANTIBODY TITRES IN SERA OF THYROTROPHIN-TREATED RABBITS WITH AND WITHOUT CORTISONE ADMINISTRATION

1962 ◽  
Vol 41 (3) ◽  
pp. 474-480 ◽  
Author(s):  
Otto Wegelius ◽  
E. J. Jokinen
Keyword(s):  
Connective Tissue ◽  
Guinea Pigs ◽  
Antibody Formation ◽  
Direct Proof ◽  
Significant Rise ◽  
Extraocular Muscles ◽  
Concomitant Treatment ◽  
Antibody Titres ◽  
Hexosamine Content ◽  
Synergetic Action

ABSTRACT In all previous investigations on experimental exophthalmos, heterologous thyrotrophic pituitary extracts have been used. These protein hormones stimulate antihormone formation in the test animals. Cortisone has been reported to effectively block antibody formation. In addition, it has been shown to potentiate TSH-induced exophthalmos in guinea-pigs. With rabbits as test animals, the hexosamine content of the orbital tissues was determined and used as an index of exophthalmos development and at the same time the antibody titres in the sera were followed. TSH injections for six weeks led to a highly significant accumulation of hexosamine in the retrobulbar connective tissue and in the extraocular muscles, i. e. an increase of up to 400% as compared with the control animals. At the same time a significant rise in antihormonal titres was detectable in the sera. Concomitant treatment with cortisone brought about an equal or higher accumulation of hexosamine but significantly lower antibody titres. The known opposite peripheral actions of TSH and cortisone can be reconciled with the synergy in producing experimental exophthalmos by attributing the synergetic action of cortisone to the blocking of antihormone formation. If less antihormones are produced, the effect of TSH is enhanced. Our experiments do not provide direct proof for this hypothesis. High hexosamine values in the orbit and low antihormone titres in the serum are, however, concomitant phenomena.

AN UNUSUAL CASE OF EXOPHTHALMOS WITH GENERAL CONNECTIVE TISSUE CHANGES

1960 ◽  
Vol XXXIII (IV) ◽  
pp. 613-622 ◽  
Author(s):  
B.-A. Lamberg ◽  
O. Wegelius ◽  
B. Kuhlbäck ◽  
C. Olin-Lamberg
Keyword(s):  
Renal Failure ◽  
Connective Tissue ◽  
Beneficial Effect ◽  
Muscle Tissue ◽  
Clinical Picture ◽  
Unusual Case ◽  
Systemic Treatment ◽  
Nasal Epithelium ◽  
Tissue Changes ◽  
Histochemical Examination

ABSTRACT A case is described of a man of 48, who presented a history and clinical picture of a solitary thyro-hypophysial syndrome with malignant exophthalmos but in which general connective tissue changes were found on histological and histochemical examination of the retrobulbar connective tissue and muscles, of the pretibial connective and muscle tissue and the nasal epithelium. The intraocular tension was increased. In addition, renal failure developed. The use of cortisol locally in the eyes had a beneficial effect on the eye syndrome. Systemic treatment with corticotrophin and prednisolone had an evident beneficial effect on the renal condition.

CONNECTIVE TISSUE CHANGES IN DIABETIC EYES

2009 ◽  
Vol 40 (3) ◽  
pp. 266-270 ◽  
Author(s):  
E. Linnér ◽  
B. Tengroth
Keyword(s):  
Connective Tissue ◽  
Tissue Changes
Sign in / Sign up

Export Citation Format

Share Document