ZUR LOKALISATION DER INNERSEKRETORISCHEN FUNKTION DES MENSCHLICHEN OVARS

1964 ◽  
Vol 46 (4) ◽  
pp. 580-596 ◽  
Author(s):  
Hartmut Brandau ◽  
Wilfried Luh

ABSTRACT The histochemical localization of some oxydative enzymes which catalize steps in the Embden-Meyerhof chain, hexosemonophosphate shunt and the citric acid cycle, was studied in normal human ovaries. In contrast to the very low concentration and homogeneous distribution of enzyme activities of the citric acid cycle in the ovarian components, the theca interna of the developing follicle and the theca and granulosa lutein cells show extremely high levels of activities of TPN-specific and glycolytic enzymes. Attempts were made to establish some relation between the findings mentioned above and the localization of hormone production. It was concluded that the synthesis of progesterone is located in the granulosa lutein cells while the formation of oestrogens takes place in the remaining ovarian components, which show a high activity of TPN-specific and glycolytic enzymes.

1970 ◽  
Vol 27 (6) ◽  
pp. 1141-1146 ◽  
Author(s):  
D. L. Liu ◽  
C. C. Walden

The caecum of the marine borer Bankia setacea was found to contain the enzymes for a modified Embden–Meyerhof pathway, a pentose cycle, and a complete citric acid cycle. The pathways are linked to the digestion of cellulose by the enzyme cellobiase. Significant numbers of bacteria were not detected in the caecum of the borer. Enzyme activities in the citric acid cycle indicate a biosynthesis role for the caecum.


1971 ◽  
Vol 67 (3) ◽  
pp. 577-589 ◽  
Author(s):  
H. Brandau ◽  
L. Brandau

ABSTRACT In an arrhenoblastoma of a 24 years old female patient the enzyme activities of the intermediary carbonhydrate metabolism, the citric acid cycle, the glycerophosphate cycle, the pentose-phosphate shunt as well as the steroid-dehydrogenases were measured quantitatively and localized histochemically. The striking high activities of the glycolytic enzymes, the presence of steroid-dehydrogenases and the only moderately increased enzyme activities of the citric acid cycle in comparison with the stroma ovarii identify the arrhenoblastoma as a tissue with steroid hormonal metabolism. High activities of the mentioned enzymes and especially the activities of the steroid-dehydrogenases were localized histochemically only in Leydig-cell-like cells. Therefore these cells may be considered as structures of steroid-biogenesis. The enzyme activity pattern of the steroiddehydrogenases illuminates the biogenetic pathways of androgens. The low activities of the 17β-hydroxysteroid-dehydrogenase in this tissue in comparison with other steroid producing tissues indicate a special testosterone metabolism.


1975 ◽  
Vol 21 (6) ◽  
pp. 869-876 ◽  
Author(s):  
A. J. S. Ball ◽  
Rita M. Bruver ◽  
E. R. Tustanoff

As a corollary to the metabolite data obtained from yeast cultures undergoing an exponential anaerobic–aerobic phase transition, levels of various glycolytic and citric acid cycle enzyme activities have been monitored in these cells. The relation of the changes in these enzyme activities in cells grown on either glucose or galactose is discussed in light of different metabolic postures these cells demonstrate as a result of their transitions.A general discussion is presented which compares the results obtained in this series of papers from both step-down and exponential transfer experiments and relates these data to control of mitochondriogenesis in yeast.


2015 ◽  
Vol 53 (8) ◽  
pp. 5582-5590 ◽  
Author(s):  
Levy W. Macedo ◽  
José H. Cararo ◽  
Soliany G. Maravai ◽  
Cinara L. Gonçalves ◽  
Giovanna M. T. Oliveira ◽  
...  

1963 ◽  
Vol 42 (4) ◽  
pp. 480-484 ◽  
Author(s):  
B. Eckstein ◽  
R. Landsberg

ABSTRACT The succinic, malic and isocitric dehydrogenases in the ovary of immature and mature, normal and serum gonadotrophin injected rats were examined. The Qo2 of these enzymes were markedly enhanced in the gonadotrophin injected rats of both age groups, except in the case of succinic dehydrogenase in the ovary of the immature rats, where a slight non-significant decrease was noted. It is concluded that in the mature rat ovary, gonadotrophin administration stimulates the activity of all the examined dehydrogenases of the citric acid cycle, whereas in the immature rat ovary, at least the isocitric- and malic dehydrogenases are thus stimulated.


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