EVALUATION OF PITUITARY ADRENAL FUNCTION IN CHILDREN

1964 ◽  
Vol 45 (3_Suppl) ◽  
pp. S13
Author(s):  
D. de Wied ◽  
T. Wiegman ◽  
B. van der Wal ◽  
]. F. Janssen ◽  
A. Delver
Keyword(s):  
Adrenal Function

IMPAIRMENT OF THE PITUITARY-ADRENAL AXIS FOLLOWING PROLONGED THERAPY WITH CORTICOTROPHIN

1970 ◽  
Vol 65 (4) ◽  
pp. 608-616 ◽  
Author(s):  
M. J. Levell ◽  
S. R. Stitch ◽  
M. J. Noronha
Keyword(s):  
Multiple Sclerosis ◽  
Adrenal Function ◽  
Withdrawal Symptoms ◽  
Prolonged Therapy ◽  
Adrenal Axis ◽  
Lysine Vasopressin ◽  
Subsequent Response ◽  
Pituitary Adrenal Axis

ABSTRACT Pituitary-adrenal function was tested in a group of 33 patients with multiple sclerosis who had been treated with corticotrophin for at least 1 year. Assessment was made by measuring the change in the plasma 11-hydroxycorticosteroid concentration following lysine vasopressin (LVP) administration. Ten patients showed abnormally small increases after LVP. Two of the 5 patients with the smallest increases still showed impairment 8 months later. The patients with no withdrawal symptoms had normal or nearly normal increases following LVP. There was an association between the concentration of 11-hydroxycorticosteroids immediately after withdrawal of ACTH and the subsequent response to LVP.

PITUITARY-ADRENAL FUNCTION IN RATS FOLLOWING LONG-TERM CORTISOL TREATMENT

1969 ◽  
Vol 61 (1_Suppl) ◽  
pp. S113
Author(s):  
J. R. Hodges ◽  
Janet Sadow
Keyword(s):  
Adrenal Function

DETERMINATION OF BLOOD CORTICOIDS USING THE IN VITRO RESIN UPTAKE OF 3H-PREDNISOLONE

1968 ◽  
Vol 57 (1) ◽  
pp. 23-32 ◽  
Author(s):  
Hironori Nakajima ◽  
Mitsunori Murala ◽  
Masumitsu Nakata ◽  
Takeshi Naruse ◽  
Seiji Kubo
Keyword(s):  
Thyroid Function Test ◽  
Normal Subjects ◽  
Adrenal Function ◽  
Function Test ◽  
Before And After ◽  
Adrenal Response ◽  
Suppression Test

ABSTRACT The in vitro resin uptake of 3H-prednisolone was used for the determination of blood cortisol after addition of radioactive prednisolone followed by Amberlite CG 400 Type 1 to the test serum, and incubation of the mixture. The radioactivity of the supernatant was compared before and after the addition of the resin. The principle of this method is similar to that of the 131I-triiodothyronine resin uptake for the thyroid function test. The tests for the specificity, reproducibility and sensitivity gave satisfactory results. The mean basal value ± SD of the 3H-prednisolone resin uptake was 35.3 ± 9.2% in normal subjects, and 27.1 ± 4.8% in pregnant women. This method was valid in various adrenal function tests, i. e. the adrenal circadian rhythm, corticotrophin (ACTH) test, dexamethasone suppression test and the adrenal response to lysine-8-vasopressin. It proved to be a sensitive indicator of the adrenal function. These results suggest that this method should be useful for a routine adrenal function test.

Recovery of the adrenal function after pituitary surgery in patients with Cushing Disease: remission or recurrence?

2018 ◽  
Author(s):  
Andreea Serban ◽  
Elisa Verrua ◽  
Elisa Sala ◽  
Marco Locatelli ◽  
Maura Arosio ◽  
...  
Keyword(s):  
Pituitary Surgery ◽  
Adrenal Function ◽  
Cushing Disease ◽  
Disease Remission
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