EFFECT OF PARTIAL INHIBITION OF β-GLUCURONIDASE ACTIVITY ON THE OESTROGEN INDUCED CHANGES IN THE RAT UTERUS

1959 ◽  
Vol 30 (1) ◽  
pp. 154-160
Author(s):  
H. A. Salmi ◽  
K. Hartiala
Keyword(s):  
Rat Uterus ◽  
Partial Inhibition ◽  
Glucuronidase Activity ◽  
Induced Changes

Diabetes-induced changes in the morphology and nociceptinergic innervation of the rat uterus

2015 ◽  
Vol 47 (1) ◽  
pp. 21-33 ◽  
Author(s):  
Saeed Tariq ◽  
Syed M. Nurulain ◽  
Hameed Rashed ◽  
Mohamed Lotfy ◽  
Starling Bright Emerald ◽  
...  
Keyword(s):  
Rat Uterus ◽  
Induced Changes

Estrogen-induced changes in the maltase activity of rat uterus

Steroids ◽  
1972 ◽  
Vol 20 (2) ◽  
pp. 173-184 ◽  
Author(s):  
M. Chitra Rao ◽  
K.P. Gunaga ◽  
Shanta S. Rao
Keyword(s):  
Rat Uterus ◽  
Maltase Activity ◽  
Induced Changes

Tamoxifen-induced changes in the polyribosomes and associated mRNA of rat uterus

1983 ◽  
Vol 32 (2-3) ◽  
pp. 233-244 ◽  
Author(s):  
Andrew P. Waters ◽  
Alan E. Wakeling ◽  
John T. Knowler
Keyword(s):  
Rat Uterus ◽  
Induced Changes

ALKALINE PHOSPHATASE AND β-GLUCURONIDASE ACTIVITY IN THE RAT UTERUS DURING EARLY PREGNANCY

1966 ◽  
Vol 35 (4) ◽  
pp. 385-391 ◽  
Author(s):  
J. P. MANNING ◽  
A. MELI ◽  
B. G. STEINETZ
Keyword(s):  
Alkaline Phosphatase ◽  
Phosphatase Activity ◽  
Early Pregnancy ◽  
Tubal Ligation ◽  
Rat Uterus ◽  
Glucuronidase Activity ◽  
Implantation Sites

SUMMARY Uterine alkaline phosphatase and β-glucuronidase activity were assayed during the first 8 days of pregnancy in rats after unilateral tubal ligation and section. The results were as follows. Alkaline phosphatase increased in the pregnant horn from days 5 to 8 while the activity of the nonpregnant horn remained unaltered. This enhanced phosphatase activity was localized exclusively at the implantation sites. β-Glucuronidase steadily decreased during the first 8 days of pregnancy in both the gravid and non-gravid horns. The occurrence of a 'peak' in β-glucuronidase activity during the oestrogen surge on day 4 of pregnancy reported previously by Prahlad (1962) was not observed. The results are discussed in relation to an interaction between the implanting blastocyst and the hormonally conditioned uterus.

The effect of oestrogen and relaxin on uterine and cervical enzymes: collagenase, proteoglycanase and β-glycuronidase

1986 ◽  
Vol 111 (3) ◽  
pp. 394-403 ◽  
Author(s):  
Catherine K. L. Too ◽  
Julianne K. Kong ◽  
F. C. Greenwood ◽  
Gillian D. Bryant-Greenwood
Keyword(s):  
Extracellular Matrix ◽  
Culture Medium ◽  
Cervical Dilatation ◽  
Rat Uterus ◽  
Inhibiting Effect ◽  
Glucuronidase Activity

Abstract. Relaxin (Rlx) classically causes uterine quiescence during pregnancy and cervical dilatation prior to parturition. Its actions involve major changes in the components of the extracellular matrix of these tissues. The activities of three enzymes, collagenase, proteoglycanase and β-glucuronidase, major determinants of the integrity of the extracellular matrix have been measured in the rat uterus and cervix in different reproductive states. The results show that there are marked differences in the changes of these enzymes occurring in the uterus and cervix during the course of pregnancy and the puerperium. It was not possible to directly relate these changes to a single hormonal event over this period of major endocrine fluctuations. Two models have therefore been used in an attempt to delineate the effects of oestrogen and Rlx on the tissue enzyme levels or their secretion into culture medium. In the first model cyclic animals were treated with oestrogen alone or oestrogen followed by Rlx and tissue enzyme levels measured. The addition of Rlx treatment reversed an inhibiting effect of oestrogen alone on both uterine and cervical collagenase and proteoglycanase activities, at the same time as completely obliterating the stimulating effect of oestrogen on uterine and cervical β-glucuronidase activity. A second model used in vivo oestrogen priming of cyclic rats followed by in vitro Rlx treatment and measurement of the enzymes secreted into the culture medium over 7 days. The results showed as in the first model that Rlx treatment could in particular overcome the inhibiting effect of oestrogen on uterine proteoglycanase secretion without affecting β-glucuronidase levels. In contrast, the effect of Rlx on the cervix was to decrease collagenase and proteoglycanase secretion whilst not affecting the β-glucuronidase levels.

Phenylethanolamine-N-methyl transferase and catechol-O-methyl transferase activity in rat uterus: Cyclic and steroid-induced changes

1993 ◽  
Vol 72 (8) ◽  
pp. 606-610 ◽  
Author(s):  
Viviane Casimiri ◽  
Wayne R. Cohen ◽  
Simone Parvez ◽  
Calvin Hobel ◽  
Hasan Parvez
Keyword(s):  
Transferase Activity ◽  
Rat Uterus ◽  
Methyl Transferase ◽  
Induced Changes
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