scholarly journals Human Liver Stem Cell Transplantation Alleviates Liver Fibrosis in a Rat Model of CCl4-Induced Liver Fibrosis

Author(s):  
Ji-Hyun Lee ◽  
Sanghoon Lee ◽  
Hey-Jung Park ◽  
Young-Ah Kim ◽  
Suk-Koo Lee
2016 ◽  
Vol 8 (2) ◽  
Author(s):  
Hiroki Hosoi ◽  
Kenji Warigaya ◽  
Shogo Murata ◽  
Toshiki Mushino ◽  
Kodai Kuriyama ◽  
...  

We report cases of three patients of refractory ascites without other fluid retention that occurred around five months after allogeneic hematopoietic stem cell transplantation (allo- HSCT). All three patients expired and postmortem examinations revealed unexpected liver fibrosis lacking histological evidences of graft-<em>versus</em>-host-disease (GVHD). The three patients showed normal hepatic function and size before transplantation. During their clinical courses, serum biochemistry test showed no elevation of hepatic enzymes and bilirubin; however, imaging studies demonstrated hepatic atrophy at the onset of ascites. One of the liver specimens showed bile obstruction, which could be seen in hepatic damage by GVHD. Although ascites resulting from venoocclusive disease in early phase allo-HSCT is well documented, ascites associated with hepatic fibrosis in late phase allo-HCST has not been reported. Further clinico-pathological studies on similar patients should be required to ascertain refractory ascites associated with liver fibrosis after allo-HSCT.


2015 ◽  
Vol 1 (4) ◽  
pp. 1-9 ◽  
Author(s):  
Kimitoshi Kubo ◽  
Shunsuke Ohnishi ◽  
Hidetaka Hosono ◽  
Moto Fukai ◽  
Ayano Kameya ◽  
...  

2008 ◽  
Vol 37 (3) ◽  
pp. 454-470 ◽  
Author(s):  
Kadiombo Bantubungi ◽  
David Blum ◽  
Laetitia Cuvelier ◽  
Sabine Wislet-Gendebien ◽  
Bernard Rogister ◽  
...  

2009 ◽  
Vol 30 (11) ◽  
pp. 1496-1504 ◽  
Author(s):  
Xue-mei Zhou ◽  
Jing-bo Sun ◽  
Hui-ping Yuan ◽  
Dong-lai Wu ◽  
Xin-rong Zhou ◽  
...  

2009 ◽  
Vol 12 (3) ◽  
pp. 187-193 ◽  
Author(s):  
Yukiko Imanishi ◽  
Shigeru Miyagawa ◽  
Satoru Kitagawa-Sakakida ◽  
Satoshi Taketani ◽  
Naosumi Sekiya ◽  
...  

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