scholarly journals The role of von Willebrand factor in determining the risk of ischemic stroke in Hawler city: a case-control study

2018 ◽  
Vol 22 (1) ◽  
pp. 120-125
Author(s):  
Sazgar Hameed ◽  
Salar Ahmed
PLoS ONE ◽  
2014 ◽  
Vol 9 (6) ◽  
pp. e99851 ◽  
Author(s):  
Peter Kraft ◽  
Christiane Drechsler ◽  
Ignaz Gunreben ◽  
Bernhard Nieswandt ◽  
Guido Stoll ◽  
...  

2009 ◽  
Vol 24 (1) ◽  
pp. 25-29 ◽  
Author(s):  
Kai-Li Shi ◽  
Bing He ◽  
Jian-Jun Wang ◽  
Li-Ping Zou

2007 ◽  
Vol 97 (04) ◽  
pp. 534-541 ◽  
Author(s):  
Vania Morelli ◽  
Marieke de Visser ◽  
Nico van Tilburg ◽  
Hans Vos ◽  
Jeroen Eikenboom ◽  
...  

SummaryABO blood group is a genetic determinant of von Willebrand factor (VWF) levels. We investigated the effect of ABO genotypes on VWF and factor VIII (FVIII) levels and on the degree to which VWF is loaded with A- and B-antigens, expressed as normalized ratios, nA-ratio and nB-ratio, respectively, in the Leiden Thrombophilia Study, a large case-control study on venous thrombosis. We found that the ABO locus had an allele-specific, dosage dependent effect on VWF and FVIII levels and on the loading of VWF with A-antigen and B-antigen. The highest mean nA- and nB-ratios were found in A 1 A 1 and BB genotypes, respectively. Four A1 O carriers had four 43-bp repeats in the minisatellite region of theABO gene in stead of the expected one repeat. All had a reduced nA-ratio compared to A 1 O carriers with one repeat in their A1 allele. The amount of A – and B- antigens expressed onVWF (nA-ratio and nB-ratio) explained about 18% (R2) of the variation in VWF levels.


2005 ◽  
Vol 12 (12) ◽  
pp. 989-993 ◽  
Author(s):  
S. Rubattu ◽  
R. Speranza ◽  
M. Ferrari ◽  
A. Evangelista ◽  
M. Beccia ◽  
...  

2017 ◽  
Vol 129 (13-14) ◽  
pp. 491-496 ◽  
Author(s):  
Marija Menih ◽  
Miljenko Križmarić ◽  
Tanja Hojs Fabjan

PLoS ONE ◽  
2020 ◽  
Vol 15 (8) ◽  
pp. e0236747
Author(s):  
Mohammad Ibrahim Khalil ◽  
Marium Salwa ◽  
Sarmin Sultana ◽  
Mohammad Abdullah Al Mamun ◽  
Nilima Barman ◽  
...  

2003 ◽  
Vol 37 (1) ◽  
pp. 51-62 ◽  
Author(s):  
Licia Denti ◽  
Alessandra Cecchetti ◽  
Valentina Annoni ◽  
Maria Francesca Merli ◽  
Fabrizio Ablondi ◽  
...  

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