Effects of a Painful Stimulus on Stress Regulation in Male Patients With Borderline Personality Disorder: A Pilot Study

2019 ◽  
Vol 33 (3) ◽  
pp. 394-412
Author(s):  
Janina Naoum ◽  
Nikolaus Kleindienst ◽  
Ulf Baumgärtner ◽  
Franziska Willis ◽  
Falk Mancke ◽  
...  
Keyword(s):  
Heart Rate ◽  
Borderline Personality Disorder ◽  
Pilot Study ◽  
Personality Disorder ◽  
Borderline Personality ◽  
Pain Stimulus ◽  
Self Injury ◽  
Significant Difference ◽  
Pain Ratings ◽  
Male Patients

Pain processing in relation to stress has so far not been investigated in male patients with borderline personality disorder (BPD). This experimental pilot study examined 17 male BPD patients and 20 male healthy controls (HCs) to assess the effects of a pain stimulus on arousal, aggression, pain (ratings), and heart rate. At baseline, BPD patients showed significantly higher arousal and aggression; however, there was no significant difference in heart rate compared to the HC group. Following stress induction, a noninvasive mechanical pain stimulus was applied. No significant differences in pain ratings or heart rates were found between the groups. For arousal, a significantly stronger decrease was revealed in the BPD group compared to the HC group (t = 2.16, p = .038). Concerning aggression, the BPD group showed a significantly greater decrease after the pain stimulus than the HC group (t = 3.25, p = .002). This data showed that nonsuicidal self-injury can reduce arousal and aggression in male BPD.

scholarly journals Incision and stress regulation in borderline personality disorder: Neurobiological mechanisms of self-injurious behaviour

2015 ◽  
Vol 207 (2) ◽  
pp. 165-172 ◽  
Author(s):  
Sarah Reitz ◽  
Rosemarie Kluetsch ◽  
Inga Niedtfeld ◽  
Teresa Knorz ◽  
Stefanie Lis ◽  
...  
Keyword(s):  
Heart Rate ◽  
Borderline Personality Disorder ◽  
Personality Disorder ◽  
Borderline Personality ◽  
Sham Treatment ◽  
Stress Regulation ◽  
Self Injury ◽  
Stress Levels ◽  
Amygdala Activity ◽  
Objective Stress

BackgroundPatients with borderline personality disorder frequently show non-suicidal self-injury (NSSI). In these patients, NSSI often serves to reduce high levels of stress.AimsInvestigation of neurobiological mechanisms of NSSI in borderline personality disorderMethodIn total, 21 women with borderline personality disorder and 17 healthy controls underwent a stress induction, followed by either an incision into the forearm or a sham treatment. Afterwards participants underwent resting-state functional magnetic resonance imaging while aversive tension, heart rate and heart rate variability were assessed.ResultsWe found a significant influence of incision on subjective and objective stress levels with a stronger decrease of aversive tension in the borderline personality disorder group following incision than sham. Amygdala activity decreased more and functional connectivity with superior frontal gyrus normalised after incision in the borderline personality disorder group.ConclusionsDecreased stress levels and amygdala activity after incision support the assumption of an influence of NSSI on emotion regulation in individuals with borderline personality disorder and aids in understanding why these patients use self-inflicted pain to reduce inner tension.

scholarly journals Paliperidone ER in the Treatment of Borderline Personality Disorder: A Pilot Study of Efficacy and Tolerability

2011 ◽  
Vol 2011 ◽  
pp. 1-7 ◽  
Author(s):  
Silvio Bellino ◽  
Paola Bozzatello ◽  
Camilla Rinaldi ◽  
Filippo Bogetto
Keyword(s):  
Borderline Personality Disorder ◽  
Pilot Study ◽  
Personality Disorder ◽  
Adverse Events ◽  
Mechanism Of Action ◽  
Severity Index ◽  
Borderline Personality ◽  
Controlled Trials ◽  
Efficacy And Safety ◽  
Dsm Iv

Antipsychotics are recommended for the treatment of impulsive dyscontrol and cognitive perceptual symptoms of borderline personality disorder (BPD). Three reports supported the efficacy of oral risperidone on BPD psychopathology. Paliperidone ER is the metabolite of risperidone with a similar mechanism of action, and its osmotic release reduces plasmatic fluctuations and antidopaminergic effects. The aim of this study is to evaluate efficacy and safety of paliperidone ER in BPD patients. 18 outpatients with a DSM-IV-TR diagnosis of BPD were treated for 12 weeks with paliperidone ER (3–6 mg/day). They were assessed at baseline, week 4, and week 12, using the CGI-Severity item, the BPRS, the HDRS, the HARS, the SOFAS, the BPD Severity Index (BPDSI), and the Barratt Impulsiveness Scale (BIS-11). Adverse events were evaluated with the DOTES. Paliperidone ER was shown to be effective and well tolerated in reducing severity of global symptomatology and specific BPD symptoms, such as impulsive dyscontrol, anger, and cognitive-perceptual disturbances. Results need to be replicated in controlled trials.

scholarly journals Gyermekkori traumatizáció, disszociáció és szándékos fizikai önsértő viselkedés borderline személyiségzavarban

2017 ◽  
Vol 158 (19) ◽  
pp. 740-747 ◽  
Author(s):  
Katalin Merza ◽  
János Harmatta ◽  
Gábor Papp ◽  
Ildikó Kuritárné Szabó
Keyword(s):  
Sexual Abuse ◽  
Borderline Personality Disorder ◽  
Personality Disorder ◽  
Significant Role ◽  
Borderline Personality ◽  
Cumulative Trauma ◽  
Self Injury ◽  
Borderline Patients ◽  
Trauma Score ◽  
Nonsuicidal Self Injury

Abstract: Introduction: Childhood traumatization plays a significant role in the etiology of borderline personality disorder. Studies found a significant association between childhood traumatization, dissociation, and nonsuicidal self-injurious behavior. Aim: The aim of our study was to assess dissociation and nonsuicidal self-injury among borderline inpatients and to reveal the association between childhood traumatization, dissociation, and self-injurious behavior. Method: The sample consisted of 80 borderline inpatients and 73 depressed control patients. Childhood traumatization, dissociation and self-injurious behavior were assessed by questionnaires. Results: Borderline patients reported severe and multiplex childhood traumatization. Cumulative trauma score and sexual abuse were the strongest predictors of dissociation. Furthermore, we have found that cumulative trauma score and dissociation were highly predictive of self-injurious behavior. Conclusion: Our results suggest that self-injurious behavior and dissociation in borderline patients can be regarded as indicators of childhood traumatization. Orv Hetil. 2017; 158(19): 740–747.

scholarly journals Non-Suicidal Self-Injury in Those Dealing With Borderline Personality Disorder or Separation from Parents

2021 ◽  
Author(s):  
Janice Valencia ◽  
Frikson Christian Sinambela
Keyword(s):  
Borderline Personality Disorder ◽  
Personality Disorder ◽  
Literature Search ◽  
Borderline Personality ◽  
Physical Injury ◽  
Self Injury ◽  
Suicidal Intention ◽  
Separation From Parents ◽  
To Receive ◽  
The Relationship

Non-suicidal self-injury (NSSI) is a deliberate destruction of one’s own body tissue without suicidal intention that causes physical injury. NSSI is mostly found in adolescents or young adults (Paul, Tsypes, Eidlitz, Ernhout, & Whitlock, 2015). Borderline personality disorder (BPD) is one of the risk factors for developing NSSI. Individuals with borderline personality disorder also experience invalidation during their childhood, this can cause individuals with BPD to feel that they deserve to receive NSSI as a form of self-punishment (Sadeh et al., 2014). In addition, children who experience parental separation (through death, divorce or employment) have a higher risk factor for developing NSSI (Astrup, Pedersen, Mok, Carr, & Webb, 2017). A literature search was conducted in six databases, and a total of 20 relevant articles were found. The explanation of the relationship between non-suicidal self-injury, borderline personality disorder, and loss of or separation from a parent are explored in this study, in order to increase understanding of how NSSI behaviours can be prevented. Keywords: NSSI, Borderline Personality, Separation Parent

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