scholarly journals Health Related Quality of Life and Psychosocial Correlates among HIV-Infected Adolescent and Young Adult Women in the US

2011 ◽  
Vol 23 (4) ◽  
pp. 367-381 ◽  
Author(s):  
Katherine Andrinopoulos ◽  
Gretchen Clum ◽  
Debra A. Murphy ◽  
Gary Harper ◽  
Lori Perez ◽  
...  
2014 ◽  
Vol 24 (7) ◽  
pp. 804-811 ◽  
Author(s):  
Lamia P. Barakat ◽  
Yimei Li ◽  
Wendy L. Hobbie ◽  
Sue K. Ogle ◽  
Thomas Hardie ◽  
...  

2011 ◽  
Vol 58 (2) ◽  
pp. 265-273 ◽  
Author(s):  
Maru Barrera ◽  
Tanya Teall ◽  
Ronald Barr ◽  
Mariana Silva ◽  
Mark Greenberg

2017 ◽  
Vol 35 (6) ◽  
pp. 652-659 ◽  
Author(s):  
Olga Husson ◽  
Brad J. Zebrack ◽  
Rebecca Block ◽  
Leanne Embry ◽  
Christine Aguilar ◽  
...  

Purpose To examine changes in health-related quality of life (HRQoL) and its predictors during the first 2 years after initial cancer diagnosis in adolescent and young adult (AYA) patients with cancer. Patients and Methods A multicenter, longitudinal, prospective study was conducted among a diverse sample of AYA patients with cancer ages 15 to 39 years. One hundred seventy-six patients (75% response) completed a self-report measure of HRQoL (Short Form-36 [SF-36]) within the first 4 months after diagnosis and again 12 and 24 months later. Linear mixed models with random intercepts and slopes estimated changes in QoL. Results Recently diagnosed AYA patients with cancer had significantly worse physical component scale (PCS) scores (38.7 v 52.8; P < .001) and mental component scale (MCS) scores (42.9 v 48.9; P < .001) when compared with population norms. Significant improvements in PCS and MCS scores from baseline to 24-month follow-up were observed; however, these increases were largest during the first 12 months. At the 24-month follow-up, AYA patients still had significantly lower PCS scores (48.0 v 52.8; P < .001) and MCS scores (45.8 v 48.9; P = .002) when compared with population norms. Multivariable analyses revealed that improvements in PCS and MCS scores were primarily a function of being off-treatment and being involved in school or work. PCS but not MCS scores were worse for AYA patients diagnosed with cancers with poorer prognoses. Conclusion Although HRQoL improved over time, it was still compromised 24 months after primary diagnosis. Given relatively little observed improvement in HRQoL during the 12- to 24-month period after diagnosis, AYA patients may benefit from supportive care interventions administered during the second year after diagnosis.


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