Advantages of Using Regression Analysis to Calculate Results of Chronic Toxicity Tests

Author(s):  
CE Stephan ◽  
JW Rogers
1988 ◽  
Vol 20 (10) ◽  
pp. 101-108 ◽  
Author(s):  
Nelson A. Thomas

A biomonitoring program has been developed in support of the National Policy for the Development of Water Quality-Based Permit Limitations for Toxic Pollutants. The program focuses on the use of laboratory toxicity tests on aquatic plants and animals to predict ecosystem impact caused by toxic pollutants. Both acute and chronic toxicity tests were developed to test effluents and ambient waters. Laboratory and biological field studies were conducted at nine sites. Single species laboratory toxicity tests were found to be good predictors of impacts on the ecosystem when two or more species were used. Biomonitoring can be undertaken either on effluents and/or on the receiving waters. In that toxicity related to seeps, leachates and storm sewers has often been found upstream from dischargers, it is beneficial to conduct both effluent and ambient biomonitoring.


Author(s):  
Patrick J. Downey ◽  
Kari Fleming ◽  
Richard Guinn ◽  
Norris Chapman ◽  
Patricia Varner ◽  
...  

1995 ◽  
Vol 29 (6) ◽  
pp. 1453-1459 ◽  
Author(s):  
Alberto Santojanni ◽  
Gessica Gorbi ◽  
Franco Sartore

2008 ◽  
Vol 33 (1) ◽  
pp. 49-53
Author(s):  
Le Quang Dung ◽  
Nguyen Duc Cu

The partial toxicity tests of copper (Cu2+), zinc (Zn2+) and cyanide (CN-) for young cobia (Rachycentron canadum) fishes 45 days-old were conducted in Doson station during ten days (yr 2005). These three toxic substances affected strongly the growth rate of the Cobia fish (length and weight of the body), even at the lowest treated concentration. The LC50 values of copper, zinc and cyanide were 0.32 mg l-1; over mg l-1 and 0,049 mg l-1, respectively. Based on the statistical analysis of growth rate of cobia by determining 1C25, IC50, NOEC and LOEC values, we have addressed the safe concentrations of these two heavy metals and cyanide in the environmental aquaculture which must be lower than 0.025 mg Cu l-1, 0.5 mg Zn l-1 and 0.005 mg CN l-1, respectively. The result also showed that cyanide was the most toxic to Cobia, followed by copper and zinc.


2021 ◽  
Author(s):  
An Xuehua ◽  
Liu Xinju ◽  
Jiang Jinhua ◽  
Wang Feidi ◽  
Lv Lu ◽  
...  

Abstract Prothioconazole (PTC) is a broad-spectrum triazole fungicide. Current research has mainly focused on its efficacy and residues, with few studies on its toxicological effects. This study assessed the effects of PTC, and its metabolite prothioconazole-desthio (PTCd), on the inhibition of activity, growth, and reproduction of Daphnia magna using acute and chronic toxicity tests. Additionally, the dose-response relationship was established to determine sensitive biological indicators. The acute toxicity test shows that the 48 h EC50 of PTC and PTCd to D. magna were 2.82 and 5.19 mg/L, respectively. The chronic toxicity of PTC and PTCd to D. magna were 0.00860 and 0.132 mg/L, respectively, with the parent compound being 15.3 times more toxic than its metabolite. The acute to chronic toxicity ratio (ACR) was calculated using chronic toxicity data, with ACR values of 227 and 27.5 for PTC and PTCd, respectively. These results indicate that both PTC and PTCd affect the growth and reproduction of D. magna, and the toxicity of the parent compound is greater than that of its metabolite. In conclusion, the metabolites of this pesticide have sufficient toxicity to harm D. magna at relevant environmental concentrations, and their environmental risk should not be neglected.


Sign in / Sign up

Export Citation Format

Share Document