Pollution-Induced Community Tolerance—A New Ecotoxicological Tool

2009 ◽  
pp. 219-219-12 ◽  
Author(s):  
H Blanck ◽  
S-Å Wängberg ◽  
S Molander
Keyword(s):  
Community Tolerance

Detection and Community Tolerance of the Mentally Ill

Soviet Review ◽  
1984 ◽  
Vol 25 (4) ◽  
pp. 3-17
Author(s):  
M. N. Liberman
Keyword(s):  
Mentally Ill ◽  
Community Tolerance

scholarly journals Non-responder phenotype reveals apparent microbiome-wide antibiotic tolerance in the murine gut

2021 ◽  
Vol 4 (1) ◽  
Author(s):  
Christian Diener ◽  
Anna C. H. Hoge ◽  
Sean M. Kearney ◽  
Ulrike Kusebauch ◽  
Sushmita Patwardhan ◽  
...  
Keyword(s):  
Antibiotic Treatment ◽  
Treatment Duration ◽  
Efflux Transporters ◽  
High Dose ◽  
Specific Host ◽  
Lactam Antibiotic ◽  
Enteric Infections ◽  
Community Tolerance ◽  
Future Work ◽  
Antibiotic Treatment Duration

AbstractBroad spectrum antibiotics cause both transient and lasting damage to the ecology of the gut microbiome. Antibiotic-induced loss of gut bacterial diversity has been linked to susceptibility to enteric infections. Prior work on subtherapeutic antibiotic treatment in humans and non-human animals has suggested that entire gut communities may exhibit tolerance phenotypes. In this study, we validate the existence of these community tolerance phenotypes in the murine gut and explore how antibiotic treatment duration or a diet enriched in antimicrobial phytochemicals might influence the frequency of this phenotype. Almost a third of mice exhibited whole-community tolerance to a high dose of the β-lactam antibiotic cefoperazone, independent of antibiotic treatment duration or dietary phytochemical amendment. We observed few compositional differences between non-responder microbiota during antibiotic treatment and the untreated control microbiota. However, gene expression was vastly different between non-responder microbiota and controls during treatment, with non-responder communities showing an upregulation of antimicrobial tolerance genes, like efflux transporters, and a down-regulation of central metabolism. Future work should focus on what specific host- or microbiome-associated factors are responsible for tipping communities between responder and non-responder phenotypes so that we might learn to harness this phenomenon to protect our microbiota from routine antibiotic treatment.

Pollution-induced community tolerance (PICT) as a tool for monitoring Lake Geneva long-term in situ ecotoxic restoration from herbicide contamination

2015 ◽  
Vol 23 (5) ◽  
pp. 4301-4311 ◽  
Author(s):  
Floriane Larras ◽  
Frédéric Rimet ◽  
Vincent Gregorio ◽  
Annette Bérard ◽  
Christophe Leboulanger ◽  
...  
Keyword(s):  
Lake Geneva ◽  
Community Tolerance

scholarly journals Pollution-induced community tolerance (PICT): towards an ecologically relevant risk assessment of chemicals in aquatic systems

2015 ◽  
Vol 61 (12) ◽  
pp. 2141-2151 ◽  
Author(s):  
Ahmed Tlili ◽  
Annette Berard ◽  
Hans Blanck ◽  
Agnes Bouchez ◽  
Fernanda Cássio ◽  
...  
Keyword(s):  
Risk Assessment ◽  
Aquatic Systems ◽  
Community Tolerance

Community Tolerance and Measures of Delinquency

1979 ◽  
Vol 16 (1) ◽  
pp. 55-79 ◽  
Author(s):  
Maynard L. Erickson ◽  
Jack P. Gibbs
Keyword(s):  
Community Tolerance
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