Modeling of Human Exposure/Dose to Benzene

2009 ◽  
pp. 280-280-11 ◽  
Author(s):  
JV Behar ◽  
JN Blancato ◽  
MD Pandian ◽  
J Thomas
Keyword(s):  
Human Exposure ◽  
Exposure Dose

scholarly journals Estimation and simulation of human exposure dose based on dynamic radiation field

2021 ◽  
Vol 7 ◽  
pp. 814-821
Author(s):  
Ming Guo ◽  
Fei Wu ◽  
Jiangbo Hu ◽  
Mohan Wang
Keyword(s):  
Radiation Field ◽  
Human Exposure ◽  
Exposure Dose

scholarly journals Study of spatiotemporal variation of atmospheric mercury and its human exposure around an integrated steel plant, India

2010 ◽  
Vol 10 (12) ◽  
pp. 5535-5549 ◽  
Author(s):  
S. Pervez ◽  
A. Koshle ◽  
Y. Pervez
Keyword(s):  
Regression Analysis ◽  
Dose Response ◽  
Human Exposure ◽  
Total Mercury ◽  
Sampling Period ◽  
Ambient Air ◽  
Exposure Dose ◽  
Mercury Content ◽  
Steel Plant ◽  
Integrated Steel Plant

Abstract. Mercury release by coal combustion has been significantly increased in India. Mercury content in coal has been analyzed to 0.272 ppm by Central Pollution Control Board. Toxicological effects of elemental Hg (Hg0) exposure include respiratory and renal failures, cardiac arrest, and cerebral oedema, while subclinical exposure may induce kidney, behavioral, and cognitive dysfunctions. The present work is focused on dispersion pattern and inter-phase exchange phenomena of ambient mercury between air-particulate matter evaluations of alongwith dominance of various major routes of human exposure-dose response using regression analysis around an integrated steel plant in central India. Source-downwind type stratified random sampling plan using longitudinal study design has been adopted for ambient monitoring of total mercury, while representative sampling plant has been adopted for persona exposure-dose response study In space-time framework. Control sites and subjects have been chosen from uncontaminated area (100 km away from any industrial activities). 06 ambient air monitoring stations and 17 subjects from workers, non-workers but local residents' categories and from controlled sites have been chosen for the study. Samples of mercury biomarkers (blood, breast milk and urine) have also been collected from same subjects in each month during sampling period. The sampling period was March 2005 to February 2006 . Samples of 30% acidified KMnO4 for air-Hg absorption, PM10, RPM and biological samples were analyzed for total mercury by ICP-AES using standard methods. Local soils and ground water were also monitored for total mercury content during the sampling period. Results have shown that mercury concentration is very high compared to prescribed limits in all receptors. Results of exchange phenomenon have shown the higher transfer of mercury from air to particulate during combustion in steel plant environment due to presence of huge amount of iron particles, in contrast to results obtained in other industrial locations earlier. Plant workers have shown 1.5 to 2.5 times higher personal RPM-Hg levels compared to Category 2 and 20–30 times higher than Category 3. All biomarkers have shown higher Hg presence compared to prescribed standards. Regression analysis between exposure routes and bio-receptors has been investigated. Dominance status of selected routes of bio-accumulation has been varied from category to category.

scholarly journals Human Exposure to Glyphosate and Methods of Detection: A Review

2020 ◽  
Vol 17 (11) ◽  
pp. 1277-1285
Author(s):  
Sunisa CHAIKLIENG ◽  
Kodchakorn UENGCHUEN
Keyword(s):  
Human Health ◽  
Human Exposure ◽  
Human Health Risk ◽  
Exposure Dose ◽  
Carcinogenic Potential ◽  
Aminomethylphosphonic Acid ◽  
Surveillance Programs ◽  
Self Harm ◽  
Environmental Air ◽  
Air Concentrations

Glyphosate is a broad-spectrum herbicide used extensively worldwide. The carcinogenic potential of glyphosate has been debated. This review aimed to describe human exposure, report environmental air concentrations in relation to occupational exposure, and identify the methods used to analyze glyphosate or AMPA concentrations. We searched, Google Scholar, Science Direct and PubMed for relevant papers in Thai or English, published from 2004 to 2017. Thus, 16 studies were identified. The results show that glyphosate and aminomethylphosphonic acid (AMPA) are markers of both internal and external exposure dose. Glyphosate is generally detected at concentrations comparable to or higher than AMPA. Human exposure has been assessed with measured levels of glyphosate ranging from 0.02 to 233 µg/L and a range of AMPA of 0.15 to 2.63 µg/L in human urine. The highest concentrations of glyphosate and AMPA found in blood were 171.1×103 and 2,600 µg/L, respectively, from acute poisonings and intentional self-harm. Environmental air concentrations of glyphosate ranged from less than 0.01 to 46.80 µg/m3 in the working field areas. Four methods used to analyze glyphosate and AMPA were identified: ELISA, HPLC-fluorescence/MS, GC-MS, LC-MS. While these results indicate the level of human exposure to glyphosate, the resulting human health effects of exposure are still uncertain. Therefore, there is a need for more investigation into human health risk assessment and application of health surveillance programs, particularly among glyphosate applicators.

scholarly journals Study of spatiotemporal variation of atmospheric mercury and its human exposure around an integrated steel plant, India

2010 ◽  
Vol 10 (1) ◽  
pp. 885-923
Author(s):  
S. Pervez ◽  
A. Koshle ◽  
Y. Pervez
Keyword(s):  
Regression Analysis ◽  
Dose Response ◽  
Human Exposure ◽  
Total Mercury ◽  
Sampling Period ◽  
Ambient Air ◽  
Exposure Dose ◽  
Mercury Content ◽  
Steel Plant ◽  
Integrated Steel Plant

Abstract. Mercury release by coal combustion has been significantly increased in India. Mercury content in coal has been analyzed to 0.272 ppm by Central Pollution Control Board. Toxicological effects of elemental Hg (Hg0) exposure include respiratory and renal failures, cardiac arrest, and cerebral oedema, while subclinical exposure may induce kidney, behavioral, and cognitive dysfunctions. The present work is focused on dispersion pattern and inter-phase exchange phenomena of ambient mercury between air-particulate matter evaluations of alongwith dominance of various major routes of human exposure-dose response using regression analysis around an integrated steel plant in central India. Source-downwind type stratified random sampling plan using longitudinal study design has been adopted for ambient monitoring of total mercury, while representative sampling plant has been adopted for persona exposure-dose response study In space-time framework. Control sites and subjects have been chosen from uncontaminated area (100 km away from any industrial activities). 06 ambient air monitoring stations and 17 subjects from workers, non-workers but local residents' categories and from controlled sites have been chosen for the study. Samples of mercury biomarkers (blood, breast milk and urine) have also been collected from same subjects in each month during sampling period. The sampling period was March 2005 to February 2006 . Samples of 30% acidified KMnO4 for air-Hg absorption, PM10, RPM and biological samples were analyzed for total mercury by ICP-AES using standard methods. Local soils and ground water were also monitored for total mercury content during the sampling period. Results have shown that mercury concentration is very high compared to prescribed limits in all receptors. Results of exchange phenomenon have shown the higher transfer of mercury from air to particulate during combustion in steel plant environment due to presence of huge amount of iron particles, in contrast to results obtained in other industrial locations earlier. Plant workers have shown 1.5 to 2.5 times higher personal RPM-Hg levels compared to Category 2 and 20–30 times higher than Category 3. All biomarkers have shown higher Hg presence compared to prescribed standards. Regression analysis between exposure routes and bio-receptors has been investigated. Dominance status of selected routes of bio-accumulation has been varied from category to category.

Chapter 8: TBE in animals

2020 ◽  
Keyword(s):  
Human Exposure ◽  
Symptomatic Disease ◽  
Tbev Infection

TBE can cause clinical symptomatic disease in dogs and horses Diagnosis of TBEV infection in animals is similar to diagnosis in humans Animals can be used as sentinels for human exposure

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