Multiple Causes for the Malformed Frog Phenomenon

2008 ◽  
pp. 233-233-30 ◽  
Author(s):  
MJ Lannoo ◽  
DR Sutherland ◽  
P Jones ◽  
D Rosenberry ◽  
RW Klaver ◽  
...  
Keyword(s):  
Multiple Causes

Multiple Diagnostic Tests Are Needed to Assess Multiple Causes of Dementia

2006 ◽  
Vol 63 (1) ◽  
pp. 144 ◽  
Author(s):  
Marcel G. M. Olde Rikkert ◽  
Wiesje M. van der Flier ◽  
Frank Erik deLeeuw ◽  
Marcel Verbeek ◽  
René W. M. M. Jansen ◽  
...  
Keyword(s):  
Diagnostic Tests ◽  
Multiple Causes

scholarly journals Placental Vacuolar ATPase Function Is a Key Link between Multiple Causes of Preeclampsia

2013 ◽  
Vol 2013 ◽  
pp. 1-9 ◽  
Author(s):  
Dongxin Zhang ◽  
Duyun Ye ◽  
Hongxiang Chen
Keyword(s):  
Molecular Mechanisms ◽  
Renin Angiotensin System ◽  
Vacuolar Atpase ◽  
Therapeutic Interventions ◽  
The Novel ◽  
Lipoxin A4 ◽  
Angiotensin System ◽  
Dihydroxyvitamin D ◽  
System 1 ◽  
Multiple Causes

Preeclampsia, a relatively common pregnancy disorder, is one of the major causes of maternal and fetal morbidity and mortality. Despite numerous research, the etiology of this syndrome remains not well understood as the pathogenesis of preeclampsia is complex, involving interaction between genetic, immunologic, and environmental factors. Preeclampsia, originating in placenta abnormalities, is induced by the circulating factors derived from the abnormal placenta. Recent work has identified various molecular mechanisms related to placenta development, including renin-angiotensin system, 1, 25-dihydroxyvitamin D, and lipoxin A4. Interestingly, advances suggest that vacuolar ATPase, a key molecule in placentation, is closely associated with them. Therefore, this intriguing molecule may represent an important link between various causes of preeclampsia. Here, we review that vacuolar ATPase works as a key link between multiple causes of preeclampsia and discuss the potential molecular mechanisms. The novel findings outlined in this review may provide promising explanations for the causation of preeclampsia and a rationale for future therapeutic interventions for this condition.

A novel polymorphism associated with lactose tolerance in Africa: multiple causes for lactase persistence?

2006 ◽  
Vol 120 (6) ◽  
pp. 779-788 ◽  
Author(s):  
Catherine J. E. Ingram ◽  
Mohamed F. Elamin ◽  
Charlotte A. Mulcare ◽  
Michael E. Weale ◽  
Ayele Tarekegn ◽  
...  
Keyword(s):  
Lactase Persistence ◽  
Lactose Tolerance ◽  
Multiple Causes
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