Capillary Gas-Liquid Chromatography Separation of Phenethylamines in Amphetamine-Positive Urine Samples

1990 ◽  
Vol 35 (6) ◽  
pp. 12979J
Author(s):  
Ann DePace ◽  
Karl Verebey ◽  
Mahmoud ElSohly
Keyword(s):  
Liquid Chromatography ◽  
Urine Samples ◽  
Gas Liquid Chromatography ◽  
Positive Urine ◽  
Liquid Chromatography Separation

Simultaneous Determination of Lactulose and Mannitol in Urine of Burn Patients by Gas-Liquid Chromatography

1992 ◽  
Vol 38 (3) ◽  
pp. 343-345 ◽  
Author(s):  
R L Shippee ◽  
A A Johnson ◽  
W G Cioffi ◽  
J Lasko ◽  
T E LeVoyer ◽  
...  
Keyword(s):  
Liquid Chromatography ◽  
Simultaneous Determination ◽  
Urine Samples ◽  
Gas Liquid Chromatography ◽  
Burn Patients ◽  
Mucosal Permeability ◽  
Severe Burns ◽  
Urine Concentrations ◽  
Enzymatic Methods

Abstract Ratios of lactulose/mannitol excretion in urine have been used to assess the extent of intestinal permeability in various disease and trauma conditions. Reported studies have used this technique to correlate altered gastrointestinal mucosal permeability to translocation of bacteria and endotoxin, leading to occult sepsis in burn patients. Enzymatic methods of analysis for urine concentrations of mannitol and lactulose were used in these studies. We have found that urine from patients with severe burns frequently contains compounds that interfere with the enzymatic methods. We describe using gas-liquid chromatography to determine mannitol and lactulose simultaneously in the urine of burn patients. To avoid the multiple peaks for the anomeric forms of the reducing sugars during precolumn trimethylsilyl derivatization, we converted the sugars to oximes before the silylation step. The method gave good recoveries of mannitol and lactulose added to burn patients' urine samples. Unlike the enzymatic methods, gas-liquid chromatography eliminates the effect of interfering compounds and allows for the simultaneous determination of both sugars in urine samples.

Quantitative Determination of Benzaldehyde in Flavors by Gas-Liquid Chromatography

1963 ◽  
Vol 46 (6) ◽  
pp. 950-951
Author(s):  
Richard L Brunelle ◽  
Glenn E Martin
Keyword(s):  
Liquid Chromatography ◽  
Liquid Phase ◽  
Benzoic Acid ◽  
Quantitative Determination ◽  
Solid Support ◽  
Specific Method ◽  
Gas Liquid Chromatography ◽  
Ultraviolet Spectrophotometry ◽  
Liquid Chromatography Separation

Abstract A rapid and specific method is given for determination of benzaldehyde in the presence of interfering substances by gas-liquid chromatography. Separation is effected on a ¼ column containing 2 5% Apiezon M as the liquid phase on a solid support of Chromoport XXX (60—80 mesh) at isothermal conditions, 100°C. The determination can be performed in the presence of benzoic acid and other interfering substances. Results are compared with those obtained by ultraviolet spectrophotometry on a variety of almond and cherry flavors.

Determination of Amphetamine and Methylamphetamine by Gas-liquid Chromatography (Head Space)

1983 ◽  
Vol 2 (2) ◽  
pp. 391-393 ◽  
Author(s):  
D. Martinez ◽  
M.P. Gimenez
Keyword(s):  
Liquid Chromatography ◽  
Solvent Extraction ◽  
Liquid Phase ◽  
Gas Phase ◽  
Urine Sample ◽  
Urine Samples ◽  
Gas Liquid Chromatography ◽  
Flame Detection ◽  
Therapeutic Doses

1 A method for determining amphetamine and methylamphetamine in urine by gas-liquid chromatography is described. 2 Chromatography is performed on a 10% Apiezon L, 10% KOH column with alkali-flame detection (NPD). This method avoids the losses of these volatile substances which are known to occur when solvent extraction is used. An alkalinized urine sample (1 ml) is introduced into a sealed vial which is heated in a water bath at 70°C for 20 min. A 1 ml portion of the gas phase in equilibrium with the liquid phase is chromatographed. 3 Amphetamine and methylamphetamine can be detected and measured in urine samples after single therapeutic doses of the drugs.

Fusel Oil Determination by Gas-Liquid Chromatography

1963 ◽  
Vol 46 (2) ◽  
pp. 294-297
Author(s):  
Glenn E Martin ◽  
Gian Caggiano ◽  
Howard Schlesinger
Keyword(s):  
Liquid Chromatography ◽  
Liquid Phase ◽  
Isothermal Condition ◽  
Solid Support ◽  
Gas Liquid Chromatography ◽  
Fusel Oil ◽  
Liquid Chromatography Separation

Abstract A method was developed for the determination of fusel oil by gas-liquid chromatography. Separation is effected in a ¼” column containing 20% Ucon polar as the liquid phase, on a solid support of Gas Chrom P at isothermal condition 90° C. The method is simple and expeditious, and the amount of each component alcohol can be determined individually.

scholarly journals A Rapid Method for Screening Urine Samples in Suspected Abuse of Cocaine

1981 ◽  
Vol 18 (6) ◽  
pp. 368-372 ◽  
Author(s):  
Lorna S F Hsu ◽  
J I Sharrard ◽  
C Love ◽  
T C Marrs
Keyword(s):  
Liquid Chromatography ◽  
Thin Layer ◽  
Thin Layer Chromatography ◽  
Rapid Method ◽  
Urine Samples ◽  
Gas Liquid Chromatography ◽  
Quick Method ◽  
Large Numbers ◽  
Layer Chromatography

We report a quick method for the detection of cocaine and its major metabolites by thin-layer chromatography with confirmation by gas-liquid chromatography. Because it is possible to use the same chloroform-isopropanol extracts of urine in both procedures, the method is convenient for screening large numbers of urine samples.

888: Metabolomic Urine Samples Profiling Using High Performance Liquid Chromatography Coupled with Mass Spectrometry to Detect Bladder Cancer

2007 ◽  
Vol 177 (4S) ◽  
pp. 295-295
Author(s):  
Michael Mullerad ◽  
Haleem J. Issaq ◽  
Alexander Kravtsov ◽  
Timothy Waybright ◽  
Brian Luke ◽  
...  
Keyword(s):  
Mass Spectrometry ◽  
Bladder Cancer ◽  
High Performance Liquid Chromatography ◽  
Liquid Chromatography ◽  
High Performance ◽  
Urine Samples
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