Full-field Laser Shearography Instrumentation for the Detection and Characterization of Fatigue Cracks in Titanium 10-2-3

2006 ◽  
Vol 3 (4) ◽  
pp. 12757 ◽  
Author(s):  
RM Groves ◽  
D Furfari ◽  
SE Barnes ◽  
SW James ◽  
S Fu ◽  
...  
Keyword(s):  
Fatigue Cracks ◽  
Full Field ◽  
Laser Shearography

scholarly journals Characterization of Liposomes Using Quantitative Phase Microscopy (QPM)

Pharmaceutics ◽  
2021 ◽  
Vol 13 (5) ◽  
pp. 590
Author(s):  
Jennifer Cauzzo ◽  
Nikhil Jayakumar ◽  
Balpreet Singh Ahluwalia ◽  
Azeem Ahmad ◽  
Nataša Škalko-Basnet
Keyword(s):  
Rapid Development ◽  
Fluorescent Labeling ◽  
Label Free ◽  
Batch Mode ◽  
Full Field ◽  
Quantitative Phase ◽  
Phase Microscopy ◽  
Quantitative Phase Microscopy ◽  
Tracking Ability

The rapid development of nanomedicine and drug delivery systems calls for new and effective characterization techniques that can accurately characterize both the properties and the behavior of nanosystems. Standard methods such as dynamic light scattering (DLS) and fluorescent-based assays present challenges in terms of system’s instability, machine sensitivity, and loss of tracking ability, among others. In this study, we explore some of the downsides of batch-mode analyses and fluorescent labeling, while introducing quantitative phase microscopy (QPM) as a label-free complimentary characterization technique. Liposomes were used as a model nanocarrier for their therapeutic relevance and structural versatility. A successful immobilization of liposomes in a non-dried setup allowed for static imaging conditions in an off-axis phase microscope. Image reconstruction was then performed with a phase-shifting algorithm providing high spatial resolution. Our results show the potential of QPM to localize subdiffraction-limited liposomes, estimate their size, and track their integrity over time. Moreover, QPM full-field-of-view images enable the estimation of a single-particle-based size distribution, providing an alternative to the batch mode approach. QPM thus overcomes some of the drawbacks of the conventional methods, serving as a relevant complimentary technique in the characterization of nanosystems.

Single-Shot Full-Field Characterization of Short Pulses by Using Temporal Annealing Modified Gerchberg–Saxton Algorithm

2017 ◽  
Vol 35 (13) ◽  
pp. 2541-2547 ◽  
Author(s):  
Zhi Qiao ◽  
Yudong Yao ◽  
Xiaochao Wang ◽  
Wei Fan ◽  
Zunqi Lin
Keyword(s):  
Single Shot ◽  
Short Pulses ◽  
Full Field

Characterization of Tensile and Compressive Behavior of Microscale Sheet Metals Using a Transparent Micro-Wedge Device

2011 ◽  
Author(s):  
James Magargee ◽  
Jian Cao ◽  
Rui Zhou ◽  
Morgan McHugh ◽  
Damon Brink ◽  
...  
Keyword(s):  
Mechanical Behavior ◽  
Thin Sheet ◽  
Thin Sheets ◽  
Stainless Steel Sheet ◽  
Sheet Metals ◽  
Compressive Behavior ◽  
Buckling Modes ◽  
Full Field ◽  
Compressive Loads

The cyclic and compressive mechanical behavior of ultra-thin sheet metals was experimentally investigated. A novel transparent wedge device was designed and fabricated to prevent the buckling of thin sheets under compressive loads, while also allowing full field strain measurements of the specimen using digital imaging methods. Thin brass and stainless steel sheet metal specimens were tested using the micro-wedge device. Experimental results show that the device can be used to delay the onset of early buckling modes of a thin sheet under compression, which is critical in examining the compressive and cyclic mechanical behavior of sheet metals.

scholarly journals Comparison of Full-Field Digital Mammography and Screen-Film Mammography for Detection and Characterization of Simulated Small Masses

2006 ◽  
Vol 187 (6) ◽  
pp. W576-W581 ◽  
Author(s):  
Wei T. Yang ◽  
Chao-Jen Lai ◽  
Gary J. Whitman ◽  
William A. Murphy ◽  
Mark J. Dryden ◽  
...  
Keyword(s):  
Digital Mammography ◽  
Full Field ◽  
Full Field Digital Mammography

scholarly journals Label-free characterization of vitrification-induced morphology changes in single-cell embryos with full-field optical coherence tomography

2015 ◽  
Vol 20 (9) ◽  
pp. 096004 ◽  
Author(s):  
Livia Zarnescu ◽  
Michael C. Leung ◽  
Michael Abeyta ◽  
Helge Sudkamp ◽  
Thomas Baer ◽  
...  
Keyword(s):  
Optical Coherence Tomography ◽  
Single Cell ◽  
Optical Coherence ◽  
Label Free ◽  
Full Field ◽  
Morphology Changes
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