Practice for Pressure Driven Membrane Separation Element/Bundle Evaluation

10.1520/d7601 ◽  
2010 ◽  
Author(s):  
Keyword(s):  
Membrane Separation ◽  
Separation Element ◽  
Pressure Driven

Separation of Biologically Active Compounds by Membrane Operations

2017 ◽  
Vol 23 (2) ◽  
pp. 218-230 ◽  
Author(s):  
Xiaoying Zhu ◽  
Renbi Bai
Keyword(s):  
Energy Consumption ◽  
Bioactive Compounds ◽  
Membrane Fouling ◽  
Membrane Separation ◽  
Separation Efficiency ◽  
High Energy ◽  
Separation Processes ◽  
Membrane Processes ◽  
Separation Technology ◽  
Pressure Driven

Background: Bioactive compounds from various natural sources have been attracting more and more attention, owing to their broad diversity of functionalities and availabilities. However, many of the bioactive compounds often exist at an extremely low concentration in a mixture so that massive harvesting is needed to obtain sufficient amounts for their practical usage. Thus, effective fractionation or separation technologies are essential for the screening and production of the bioactive compound products. The applicatons of conventional processes such as extraction, distillation and lyophilisation, etc. may be tedious, have high energy consumption or cause denature or degradation of the bioactive compounds. Membrane separation processes operate at ambient temperature, without the need for heating and therefore with less energy consumption. The “cold” separation technology also prevents the possible degradation of the bioactive compounds. The separation process is mainly physical and both fractions (permeate and retentate) of the membrane processes may be recovered. Thus, using membrane separation technology is a promising approach to concentrate and separate bioactive compounds. Methods: A comprehensive survey of membrane operations used for the separation of bioactive compounds is conducted. The available and established membrane separation processes are introduced and reviewed. Results: The most frequently used membrane processes are the pressure driven ones, including microfiltration (MF), ultrafiltration (UF) and nanofiltration (NF). They are applied either individually as a single sieve or in combination as an integrated membrane array to meet the different requirements in the separation of bioactive compounds. Other new membrane processes with multiple functions have also been developed and employed for the separation or fractionation of bioactive compounds. The hybrid electrodialysis (ED)-UF membrane process, for example has been used to provide a solution for the separation of biomolecules with similar molecular weights but different surface electrical properties. In contrast, the affinity membrane technology is shown to have the advantages of increasing the separation efficiency at low operational pressures through selectively adsorbing bioactive compounds during the filtration process. Conclusion: Individual membranes or membrane arrays are effectively used to separate bioactive compounds or achieve multiple fractionation of them with different molecule weights or sizes. Pressure driven membrane processes are highly efficient and widely used. Membrane fouling, especially irreversible organic and biological fouling, is the inevitable problem. Multifunctional membranes and affinity membranes provide the possibility of effectively separating bioactive compounds that are similar in sizes but different in other physical and chemical properties. Surface modification methods are of great potential to increase membrane separation efficiency as well as reduce the problem of membrane fouling. Developing membranes and optimizing the operational parameters specifically for the applications of separation of various bioactive compounds should be taken as an important part of ongoing or future membrane research in this field.

Roles of surfactants in pressure-driven membrane separation processes: a review

2019 ◽  
Vol 26 (30) ◽  
pp. 30731-30754 ◽  
Author(s):  
Lixiu Shi ◽  
Jinhui Huang ◽  
Guangming Zeng ◽  
Lei Zhu ◽  
Yanling Gu ◽  
...  
Keyword(s):  
Membrane Separation ◽  
Separation Processes ◽  
Pressure Driven

Modelling of pressure-driven membrane separation of electrolytes.

1998 ◽  
Vol 142 (2) ◽  
pp. 205-212
Author(s):  
Alexander G. Maryasov ◽  
George L. Semin
Keyword(s):  
Membrane Separation ◽  
Pressure Driven
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