scholarly journals The Role of Ultrasonography for Differentiating and Management of Malignant Cervical Lymph Nodes

2016 ◽  
Vol 13 (1) ◽  
Author(s):  
Serap Dogan ◽  
Afra Yildirim ◽  
Refika Erbakirci ◽  
Aylin Okur ◽  
Sedat Cagli ◽  
...  
Keyword(s):  
Lymph Nodes ◽  
Cervical Lymph Nodes

scholarly journals Evaluation of the role of sono-elastography in diagnosis of enlarged cervical lymph nodes

2017 ◽  
Vol 48 (2) ◽  
pp. 381-391
Author(s):  
Mohamed Ahmed Moharram ◽  
Noha Mohamed Abd-El Maboud ◽  
Heba A. Elaziz Ahmed
Keyword(s):  
Lymph Nodes ◽  
Cervical Lymph Nodes

Cervical lymph nodes play the role of regional lymph nodes in brain tumour immunity in rats

1999 ◽  
Vol 25 (2) ◽  
pp. 113-122 ◽  
Author(s):  
Okamoto ◽  
Yamashita ◽  
Hasegawa ◽  
Fujisawa ◽  
Yamashima ◽  
...  
Keyword(s):  
Lymph Nodes ◽  
Brain Tumour ◽  
Regional Lymph Nodes ◽  
Cervical Lymph Nodes ◽  
Tumour Immunity

scholarly journals ROLE OF FNAC IN THE EVALUATION OF CERVICAL LYMPH NODES: A HOSPITAL BASED STUDY

2015 ◽  
Vol 4 (55) ◽  
pp. 9643-9648
Author(s):  
Jyo ti Priyadarshini Shrivastava ◽  
Alok Shrivastava ◽  
Sandeep Singh ◽  
Rajesh Gaur
Keyword(s):  
Lymph Nodes ◽  
Cervical Lymph Nodes

scholarly journals The role of NUPR1 in lymphocyte proliferation and apoptosis

2017 ◽  
Vol 69 (2) ◽  
pp. 261-267
Author(s):  
Milica Vujicic ◽  
Bobana Vasic ◽  
Ivana Nikolic ◽  
Tamara Saksida ◽  
Ivana Stojanovic
Keyword(s):  
Lymph Nodes ◽  
Cellular Response ◽  
Immune Cell ◽  
Kinase Inhibitor ◽  
Cervical Lymph Nodes ◽  
Transcription Cofactor ◽  
Proliferation And Apoptosis ◽  
Induced Apoptosis

Nuclear protein 1 (NUPR1) is a transcription cofactor that senses stressful conditions and modulates cellular response by promoting or inhibiting apoptosis. NUPR1 is usually highly expressed in tumor cells where it enables them to adapt and resist environmental stress or chemotherapeutic compounds. NUPR1 can be involved in cell proliferation. Data about the involvement of NUPR1 in the proliferation and apoptosis of lymphocytes are scarce. Therefore, in this study we focused on the role of NUPR1 in lymphocyte physiology and found that NUPR1 might be involved in the initiation of their proliferation. Lymphocytes were isolated from the cervical lymph nodes of C57BL/6 mice. NUPR1 expression subsided 24 h after the induction of proliferation by a mitogen. Also, stressful conditions after cell isolation led to increased NUPR1 mRNA and protein expression in vitro that coincided with cell apoptosis. Similarly, apoptosis induction by staurosporine, a broad-range protein kinase inhibitor, led to increased NUPR1 expression. In addition, NUPR1 inhibition by smallinterfering RNA prevented the staurosporine-induced apoptosis (judging from decreased caspase activity) in the whole cell population of cervical lymph nodes. However, NUPR1 absence was irrelevant to the induction of apoptosis in CD3+ T lymphocytes, suggesting that NUPR1 is probably a mediator of apoptosis in other immune cell populations within the lymph node, such as B lymphocytes. In conclusion, our results suggest that NUPR1 is important for the initiation of lymphocyte cell division and for the apoptotic process of non-T cells during stressful conditions.

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