Migraine and its association with stroke is a topic that has received much attention due to the high prevalence of migraine and the often devastating outcomes of stroke. There is a nearly two-fold increased risk of stroke in patients with migraine. In addition, this risk is higher in younger adults, particularly women under 45 years old, and in those with increased frequency of migraine with aura attacks. This chapter seeks to explore migraine-induced stroke, migrainous infarction, as well as the risk associated with ischemic stroke in patients with migraines. Furthermore, proposed mechanisms for stroke related to migraine, such as cortical spreading depression, arterial dissection, and patent foramen ovale, will be discussed.
Migrainous Infarction and Cortical Spreading Depression