scholarly journals Application of Multivariate Calibration Methods, in Dissolution Testing and Simultaneous Determination of Atorvastatin and Ezetimibe in Their Combined Solid Dosage Form

2016 ◽  
Vol 22 (2) ◽  
pp. 105-111 ◽  
Author(s):  
Azin Jahangiri ◽  
Khosro Adibkia ◽  
Karim Asadpour-Zeynali ◽  
Yousef Javadzadeh ◽  
Hamed Hamishehkar ◽  
...  
Keyword(s):  
Simultaneous Determination ◽  
Dosage Form ◽  
Multivariate Calibration ◽  
Dissolution Testing ◽  
Solid Dosage Form ◽  
Solid Dosage ◽  
Calibration Methods

scholarly journals Development and Validation of RP-HPLC Method for the Simultaneous Determination of Rabeprazole Sodium and Itopride Hydrochloride in Solid Dosage Form

2010 ◽  
Vol 7 (3) ◽  
pp. 947-952 ◽  
Author(s):  
Rajesh Sharma ◽  
Ganesh Prasad Mishra ◽  
Subhash Chandra Chaturvedi
Keyword(s):  
Simultaneous Determination ◽  
High Performance ◽  
Dosage Form ◽  
High Performance Liquid Chromatographic ◽  
Hplc Method ◽  
Solid Dosage Form ◽  
Solid Dosage ◽  
Rabeprazole Sodium ◽  
Itopride Hydrochloride

A simple, sensitive, precise, accurate, rapid and reproducible reverse phase high performance liquid chromatographic procedure is developed for simultaneous determination of rabeprazole sodium and itopride hydrochloride in solid dosage form. The mobile phase used was a combination of acetonitrile: buffer (35:65 v/v) and the pH was adjusted to 7.0 ± 0.1 by addition of triethylamine. The detection of the capsule dosage form was carried out at 266 nm and a flow rate employed was 1 mL/min. Linearity was obtained in the concentration range of 2 to 16 μg/mL of rabeprazole sodium and 5 to 55 μg/mL of itopride hydrochloride with a correlation coefficient of 0.9992 and 0.9996 respectively. The results of the analysis were validated statistically and recovery studies confirmed the accuracy of the proposed method.

Cyclic voltammetric simultaneous determination of oxidizable amino acids using multivariate calibration methods

2000 ◽  
Vol 405 (1-2) ◽  
pp. 153-160 ◽  
Author(s):  
Javier Saurina ◽  
Santiago Hernández-Cassou ◽  
Esteve Fàbregas ◽  
Salvador Alegret
Keyword(s):  
Amino Acids ◽  
Simultaneous Determination ◽  
Multivariate Calibration ◽  
Cyclic Voltammetric ◽  
Calibration Methods
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