scholarly journals Variability of the Cyclin-Dependent Kinase 2 Flexibility Without Significant Change in the Initial Conformation of the Protein or Its Environment; a Computational Study

2016 ◽  
Vol 14 (2) ◽  
pp. 1-12
Author(s):  
Mohammad Taghizadeh ◽  
Bahram Goliaei ◽  
Armin Madadkar-Sobhani
2007 ◽  
Vol 13 (30) ◽  
pp. 8437-8444 ◽  
Author(s):  
Marco De Vivo ◽  
Andrea Cavalli ◽  
Paolo Carloni ◽  
Maurizio Recanatini

Química Nova ◽  
2017 ◽  
Author(s):  
Ricardo Vivas-Reyes ◽  
Juan Torres ◽  
Juan Toro ◽  
Rosa Baldiris ◽  
Javier Vergara

Author(s):  
Cynthia L. Ogden ◽  
Margaret D. Carroll ◽  
Margaret A. McDowell ◽  
Katherine M. Flegal

2005 ◽  
Vol 25 (1_suppl) ◽  
pp. S309-S309
Author(s):  
Svetlana Pundik ◽  
W David Lust ◽  
Jose Valerio ◽  
Michael Buczek ◽  
Randall D York ◽  
...  

1992 ◽  
Vol 67 (01) ◽  
pp. 060-062 ◽  
Author(s):  
J Harsfalvi ◽  
E Tarcsa ◽  
M Udvardy ◽  
G Zajka ◽  
T Szarvas ◽  
...  

Summaryɛ(γ-glutamyl)lysine isodipeptide has been detected in normal human plasma by a sensitive HPLC technique in a concentration of 1.9-3.6 μmol/1. Incubation of in vitro clotted plasma at 37° C for 12 h resulted in an increased amount of isodipeptide, and there was no further significant change when streptokinase was also present. Increased in vivo isodipeptide concentrations were also observed in hypercoagulable states and during fibrinolytic therapy.


1961 ◽  
Vol 06 (03) ◽  
pp. 498-503 ◽  
Author(s):  
W Doleschel ◽  
W Auerswald

SummaryDuring “spontaneous” activation of a human euglobulin preparation in suitably spaced samples — while plasminogen became progressively converted into piasmin — the proactivator content was tested by addition of equal amounts of streptokinase and evaluation of the lytic activities on heated and normal bovine fibrin plates. Indepedently of the decreasing content of plasminogen the proactivator which could be activated by streptokinase showed no significant change of concentration. These observation indicate that plasminogen is not acting as proactivator and that there exists a separate proactivator-activator system of the fibrinolytic mechanism in human serum.


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