scholarly journals Acute and Subchronic Toxicity Study of the Median Septum of Juglans regia in Wistar Rats

2016 ◽  
Vol 6 (4) ◽  
pp. 541-549 ◽  
Author(s):  
Asma Ravanbakhsh ◽  
Majid Mahdavi ◽  
Ghader Jalilzade-Amin ◽  
Shahram Javadi ◽  
Masoud Maham ◽  
...  
Keyword(s):  
Wistar Rats ◽  
Juglans Regia ◽  
Toxicity Study ◽  
Subchronic Toxicity ◽  
Median Septum

scholarly journals Safety assessment of Euglena gracilis ATCC 12894 whole cell biomass

2019 ◽  
Vol 3 ◽  
pp. 239784731989522
Author(s):  
Jennifer Symonds ◽  
Chonggang Zhang ◽  
Adam Noble ◽  
Claire Kruger
Keyword(s):  
Euglena Gracilis ◽  
Safety Assessment ◽  
Wistar Rats ◽  
Micronucleus Assay ◽  
Toxicity Study ◽  
Subchronic Toxicity ◽  
Whole Cell ◽  
Reverse Mutation ◽  
Test Article ◽  
Cell Biomass

A safety assessment of the dried whole cell biomass of Euglena gracilis ATCC 12894 was performed by the bacterial reverse mutation (Ames) assay, an in vitro micronucleus assay, and a 90-day repeat oral toxicity study in Wistar rats. E. gracilis ATCC 12894 whole cell biomass has no added excipients and contains 33.8% protein, 28.8% β-glucans, 19.8% fat, 7.1% ash, and 2.8% moisture. The bacterial reverse mutation assay found no evidence of mutagenicity after exposure to E. gracilis ATCC 12894 whole cell biomass, with or without metabolic activity, at levels up to 1581 µg/plate, the limit dose for the assay. Similarly, no evidence of genotoxicity was observed in the micronucleus assay, with or without metabolic activation, up to 320 µg/mL, the limit dose for the assay. The subchronic toxicity study was performed with the following test article dose groups: 0 (control), 1250, 2500, and 5000 mg/kg/day, administered to male and female Wistar rats via oral gavage for 90 days. No test article-related mortalities or adverse events were reported during the study. Histopathological examination revealed some vacuolation in the livers of males in the 5000 mg/kg/day group. This finding was considered adaptive, due to the approximately 20% fat content of whole cell biomass, and was therefore test article-related, but not adverse. No such findings were reported in female rats in the study. The results of the subchronic toxicity study describe a no observed adverse effect level of at least 5000 mg/kg/day.

A subchronic toxicity study of shea nut color in Wistar rats

2003 ◽  
Vol 41 (11) ◽  
pp. 1537-1542 ◽  
Author(s):  
Y. Kitamura ◽  
A. Nishikawa ◽  
F. Furukawa ◽  
H. Nakamura ◽  
K. Okazaki ◽  
...  
Keyword(s):  
Wistar Rats ◽  
Toxicity Study ◽  
Subchronic Toxicity

Subchronic toxicity study of ulvan from Ulva pertusa (Chlorophyta) in Wistar rats

2013 ◽  
Vol 62 ◽  
pp. 573-578 ◽  
Author(s):  
Huimin Qi ◽  
Xiaolei Liu ◽  
Kai Wang ◽  
Dongmei Liu ◽  
Liye Huang ◽  
...  
Keyword(s):  
Wistar Rats ◽  
Toxicity Study ◽  
Ulva Pertusa ◽  
Subchronic Toxicity

scholarly journals Subchronic Toxicity Study of the Extract of Sacoglottis gabonensis (Baille) Urban (Humiriaceae) in Wistar Rats

2018 ◽  
Vol 24 (1) ◽  
pp. 1-10
Author(s):  
Tra Bi Irié Otis ◽  
Kouassi Kousso Brigitte ◽  
Gnangoran Boua Narcisse ◽  
Kone Mama ◽  
Yapo Angoué Paul
Keyword(s):  
Wistar Rats ◽  
Toxicity Study ◽  
Subchronic Toxicity

Subchronic Toxicity Study of Aqueous Infusion from Cotinus coggygria Leaves in Wistar Rats

2013 ◽  
Vol 66 (5) ◽  
Author(s):  
Danail Pavlov ◽  
Milka Nashar ◽  
Miroslav Eftimov ◽  
Kalin Kalchev ◽  
Stefka Valcheva-Kuzmanova ◽  
...  
Keyword(s):  
Wistar Rats ◽  
Toxicity Study ◽  
Subchronic Toxicity ◽  
Cotinus Coggygria

Toxicity Study of Swarna Bhasma, an Ayurvedic Medicine Containing Gold, in Wistar Rats

2015 ◽  
Vol 22 (3) ◽  
pp. 11 ◽  
Author(s):  
Pallavi Shrirang Jamadagni ◽  
Shrirang B. Jamadagni ◽  
Arjun Singh ◽  
Rajendra Kumar Singh ◽  
Sachchidanand N. Upadhyay ◽  
...  
Keyword(s):  
Wistar Rats ◽  
Toxicity Study ◽  
Ayurvedic Medicine

scholarly journals Acute and subchronic toxicity study of nonpolar extract of licorice roots in mice

2020 ◽  
Vol 8 (5) ◽  
pp. 2242-2250
Author(s):  
Hyun‐Yong Kim ◽  
Guanglei Zuo ◽  
Soo Kyeong Lee ◽  
Soon Sung Lim
Keyword(s):  
Toxicity Study ◽  
Subchronic Toxicity

Subchronic toxicity of cerium nitrate by 90-day oral exposure in wistar rats

2019 ◽  
Vol 108 ◽  
pp. 104474 ◽  
Author(s):  
Yu Wu ◽  
Xiaoqiao Tang ◽  
Wenxiang Yang ◽  
Jun Fan ◽  
Lijun Tang ◽  
...  
Keyword(s):  
Wistar Rats ◽  
Cerium Nitrate ◽  
Oral Exposure ◽  
Subchronic Toxicity
Sign in / Sign up

Export Citation Format

Share Document