scholarly journals The Effect of Bone Marrow Mesenchymal Stem Cells on Vitamin D3 Induced Monocytic Differentiation of U937 Cells

2016 ◽  
Vol 6 (1) ◽  
pp. 23-29 ◽  
Author(s):  
Zahra Molaeipour ◽  
Karim Shamsasanjan ◽  
Ali Akbari Movassaghpour ◽  
Parvin Akbarzadehlaleh ◽  
Fatemeh Sabaghi ◽  
...  
Keyword(s):  
Stem Cells ◽  
Bone Marrow ◽  
Mesenchymal Stem Cells ◽  
Vitamin D3 ◽  
U937 Cells ◽  
Monocytic Differentiation ◽  
Marrow Mesenchymal Stem Cells

scholarly journals Magnesium Is a Key Regulator of the Balance between Osteoclast and Osteoblast Differentiation in the Presence of Vitamin D3

2019 ◽  
Vol 20 (2) ◽  
pp. 385 ◽  
Author(s):  
Fabiana Mammoli ◽  
Sara Castiglioni ◽  
Sandra Parenti ◽  
Concettina Cappadone ◽  
Giovanna Farruggia ◽  
...  
Keyword(s):  
Stem Cells ◽  
Bone Marrow ◽  
Mesenchymal Stem Cells ◽  
Vitamin D3 ◽  
Bone Health ◽  
Osteoblast Differentiation ◽  
U937 Cells ◽  
Low Concentrations ◽  
High Concentrations ◽  
Osteoclastic Differentiation

Magnesium (Mg) is crucial for bone health. Low concentrations of Mg inhibit the activity of osteoblasts while promoting that of osteoclasts, with the final result of inducing osteopenia. Conversely, little is known about the effects of high concentrations of extracellular Mg on osteoclasts and osteoblasts. Since the differentiation and activation of these cells is coordinated by vitamin D3 (VD3), we investigated the effects of high extracellular Mg, as well as its impact on VD3 activity, in these cells. U937 cells were induced to osteoclastic differentiation by VD3 in the presence of supra-physiological concentrations (>1 mM) of extracellular Mg. The effect of high Mg concentrations was also studied in human bone-marrow-derived mesenchymal stem cells (bMSCs) induced to differentiate into osteoblasts by VD3. We demonstrate that high extra-cellular Mg levels potentiate VD3-induced osteoclastic differentiation, while decreasing osteoblastogenesis. We hypothesize that Mg might reprogram VD3 activity on bone remodeling, causing an unbalanced activation of osteoclasts and osteoblasts.

scholarly journals Study on the bone marrow mesenchymal stem cells induced drug resistance in the U937 cells and its mechanism

2006 ◽  
Vol 119 (11) ◽  
pp. 905-910 ◽  
Author(s):  
Yu-mei LIN ◽  
Gui-zhen ZHANG ◽  
Zong-xiang LENG ◽  
Zhen-xia LU ◽  
Li-sha BU ◽  
...  
Keyword(s):  
Stem Cells ◽  
Bone Marrow ◽  
Drug Resistance ◽  
Mesenchymal Stem Cells ◽  
U937 Cells ◽  
Marrow Mesenchymal Stem Cells

In vitro effect of prolactin on the osteogenic potential of bone marrow mesenchymal stem cells of rats

2013 ◽  
Author(s):  
Melo Ocarino Natalia de ◽  
Silvia Silva Santos ◽  
Lorena Rocha ◽  
Juneo Freitas ◽  
Reis Amanda Maria Sena ◽  
...  
Keyword(s):  
Stem Cells ◽  
Bone Marrow ◽  
Mesenchymal Stem Cells ◽  
Osteogenic Potential ◽  
Marrow Mesenchymal Stem Cells ◽  
Vitro Effect

Effect of lactation on the osteogenic potential of bone marrow mesenchymal stem cells of rats

2014 ◽  
Author(s):  
Reis Amanda Maria Sena ◽  
Freitas Silva Juneo de ◽  
Silvia Silva Santos ◽  
Rogeria Serakides ◽  
Melo Ocarino Natalia de
Keyword(s):  
Stem Cells ◽  
Bone Marrow ◽  
Mesenchymal Stem Cells ◽  
Osteogenic Potential ◽  
Marrow Mesenchymal Stem Cells

Tracking Observation of Cynomolgus Monkey Bone Marrow Mesenchymal Stem Cells Labeled with Feridex after Autologus Transplantation

2013 ◽  
Vol 28 (3) ◽  
pp. 224-231
Author(s):  
Zhenhua REN ◽  
Jiayin WANG ◽  
Shuyan WANG ◽  
Ying ZHANG ◽  
Chunlin ZOU ◽  
...  
Keyword(s):  
Stem Cells ◽  
Bone Marrow ◽  
Mesenchymal Stem Cells ◽  
Cynomolgus Monkey ◽  
Marrow Mesenchymal Stem Cells
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