Immobilization of Lipase on Iron Oxide Organic/Inorganic Hybrid Particles: A Review Article

2018 ◽  
Vol 53 (1) ◽  
pp. 106-117 ◽  
Author(s):  
Zafar Ali ◽  
Tian Li ◽  
Muhammad Khan ◽  
Nisar Ali ◽  
Qiuyu Zhang

Abstract In last few decades the demand of lipase has been dramatically increase due to its useful use in numbers of biochemical industries. Varieties of natural and synthetic carriers and methodologies have been used to improve lipase activities by the process of immobilization in order to enhance its activities in term of its resistance to high temperature, pH and to increase its reusibity and storage capacity. Due to the expensive nature the recycling of the lipase has been the target of the researchers to decrease its cost in the industrial process. Magnetic iron oxide organic/inorganic hybrid nanoparticles as a support have been mostly used in the lipase immobilization due its large surface area, less toxicity, bio compatibility, easily functionalization, separation avoiding long time consuming process like filtration and centrifuging.

2009 ◽  
Vol 1189 ◽  
Author(s):  
Dickson K Kirui ◽  
Carl A Batt

AbstractMagnetofluorescent hybrid nanoparticles consisting of Au layer, an iron oxide moiety, and fluorescent molecules could provide a promising platform for development of multimodal imaging and therapy approaches in the treatment of cancer. However, the feasibility of this platform has yet to be fully explored. In this study, we synthesized biocompatible dumbbell-like iron-gold hybrid particles that are superparamagnetic, fluorescent and with strong optical absorption. Furthermore, we showed that hybrid nanoparticles can be conjugated to targeting agents allowing for specific targeting of cancer cells.


RSC Advances ◽  
2015 ◽  
Vol 5 (40) ◽  
pp. 31920-31929 ◽  
Author(s):  
Moritz von der Lühe ◽  
Ulrike Günther ◽  
Andreas Weidner ◽  
Christine Gräfe ◽  
Joachim H. Clement ◽  
...  

We report on the coating of superparamagnetic iron oxide nanoparticles using polyanionic or polyzwitterionic materials based on polydehydroalanine. The resulting core–shell hybrid nanoparticles exhibit shells of different charge and thickness.


Langmuir ◽  
2008 ◽  
Vol 24 (22) ◽  
pp. 13197-13202 ◽  
Author(s):  
Hai-Tao Zhang ◽  
Jun Ding ◽  
Gan-Moog Chow ◽  
Zhi-Li Dong

Sensors ◽  
2019 ◽  
Vol 19 (6) ◽  
pp. 1339 ◽  
Author(s):  
Hasan Islam ◽  
Dmitrij Lagutin ◽  
Antti Ylä-Jääski ◽  
Nikos Fotiou ◽  
Andrei Gurtov

The Constrained Application Protocol (CoAP) is a specialized web transfer protocol which is intended to be used for constrained networks and devices. CoAP and its extensions (e.g., CoAP observe and group communication) provide the potential for developing novel applications in the Internet-of-Things (IoT). However, a full-fledged CoAP-based application may require significant computing capability, power, and storage capacity in IoT devices. To address these challenges, we present the design, implementation, and experimentation with the CoAP handler which provides transparent CoAP services through the ICN core network. In addition, we demonstrate how the CoAP traffic over an ICN network can unleash the full potential of the CoAP, shifting both overhead and complexity from the (constrained) endpoints to the ICN network. The experiments prove that the CoAP Handler helps to decrease the required computation complexity, communication overhead, and state management of the CoAP server.


1975 ◽  
Vol 65 (2) ◽  
pp. 359-372 ◽  
Author(s):  
H J Reimers ◽  
D J Allen ◽  
I A Feuerstein ◽  
J F Mustard

Repeated thrombin treatment of washed platelets prepared from rabbits can decrease the serotonin content of the platelets by about 80%. When these platelets are deaggregated they reaccumulate serotonin but their storage capacity for serotonin is reduced by about 60%. If thrombin-pretreated platelets are allowed to equilibrate with a high concentration of serotonin (123 mu M), they release a smaller percentage of their total serotonin upon further thrombin treatment, in comparison with the percentage of serotonin released from control platelets equilibrated with the same concentration of serotonin calculations indicate that in thrombin-treated platelets reequilibrated with serotonin, two-thirds of the serotonin is in the granule compartment and one-third is in the extragranular compartment, presumably the cytoplasm. Analysis of the exchange of serotonin between the suspending fluid and the platelets showed that thrombin treatment does not alter the transport rate of serotonin across the platelet membrane and does not cause increased diffusion of serotonin from the platelets into the suspending fluid. The primary reason for the reduced serotonin accumulation by the thrombin-treated platelets appears to be loss of amine storage granules or of the storage capacity within the granules.


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