A randomized trial of tight vs. less tight control of mild essential and gestational hypertension in pregnancy

2008 ◽  
Vol 36 (5) ◽  
Author(s):  
Alaa A. El Guindy ◽  
Ashraf F. Nabhan
Keyword(s):  
Randomized Trial ◽  
Gestational Hypertension ◽  
Tight Control ◽  
Hypertension In Pregnancy ◽  
In Pregnancy

scholarly journals Less-Tight Versus Tight Control of Hypertension in Pregnancy

2015 ◽  
Vol 70 (5) ◽  
pp. 307-308 ◽  
Author(s):  
Laura A. Magee ◽  
Peter von Dadelszen ◽  
Evelyne Rey ◽  
Susan Ross ◽  
Elizabeth Asztalos ◽  
...  
Keyword(s):  
Tight Control ◽  
Hypertension In Pregnancy ◽  
In Pregnancy

scholarly journals Dopamine in the Pathophysiology of Preeclampsia and Gestational Hypertension: Monoamine Oxidase (MAO) and Catechol-O-methyl Transferase (COMT) as Possible Mechanisms

2019 ◽  
Vol 2019 ◽  
pp. 1-8 ◽  
Author(s):  
Wendy N. Phoswa
Keyword(s):  
Monoamine Oxidase ◽  
Gestational Hypertension ◽  
Morbidity And Mortality ◽  
Therapeutic Interventions ◽  
Hypertensive Disorders Of Pregnancy ◽  
Methyl Transferase ◽  
Hypertension In Pregnancy ◽  
Health Burden ◽  
Hypertensive Disorders ◽  
In Pregnancy

Purpose of the Review. Hypertension in pregnancy is the global health burden. Amongst the hypertensive disorders of pregnancy, preeclampsia and gestational hypertension are the world’s leading disorders that lead to both maternal and fetal morbidity and mortality. Recent Findings. Dopamine inactive metabolites, namely, monoamine oxidase (MAO) and catechol-O-methyl transferase (COMT), have been reported to be associated with hypertensive disorders of pregnancy such preeclampsia and gestational hypertension. Summary. This review discusses the involvement of MAO and COMT in the pathophysiology of both conditions in order to have a better understanding on the pathogenesis of both conditions, suggesting promising therapeutic interventions and subsequently reducing maternal and fetal morbidity and mortality.

scholarly journals Hypertension in pregnancy: Pathophysiology and treatment

2019 ◽  
Vol 7 ◽  
pp. 205031211984370 ◽  
Author(s):  
Stephanie Braunthal ◽  
Andrei Brateanu
Keyword(s):  
Gestational Hypertension ◽  
Severe Hypertension ◽  
Organ Damage ◽  
Morbidity And Mortality ◽  
Perinatal Morbidity ◽  
Hypertensive Disorders Of Pregnancy ◽  
Hypertension In Pregnancy ◽  
Hypertensive Disorders ◽  
In Pregnancy ◽  
The Ideal

Hypertensive disorders of pregnancy, an umbrella term that includes preexisting and gestational hypertension, preeclampsia, and eclampsia, complicate up to 10% of pregnancies and represent a significant cause of maternal and perinatal morbidity and mortality. Despite the differences in guidelines, there appears to be consensus that severe hypertension and non-severe hypertension with evidence of end-organ damage need to be controlled; yet the ideal target ranges below 160/110 mmHg remain a source of debate. This review outlines the definition, pathophysiology, goals of therapy, and treatment agents used in hypertensive disorders of pregnancy.

scholarly journals Less-Tight versus Tight Control of Hypertension in Pregnancy

2015 ◽  
Vol 372 (5) ◽  
pp. 407-417 ◽  
Author(s):  
Laura A. Magee ◽  
Peter von Dadelszen ◽  
Evelyne Rey ◽  
Susan Ross ◽  
Elizabeth Asztalos ◽  
...  
Keyword(s):  
Tight Control ◽  
Hypertension In Pregnancy ◽  
In Pregnancy

199. Oral antihypertensive treatment of severe hypertension in pregnancy – A randomized trial of 3 regimens

2018 ◽  
Vol 13 ◽  
pp. S30-S31 ◽  
Author(s):  
Thomas Easterling ◽  
Shuchita Mundle ◽  
Hillary Bracken ◽  
Laura Magee ◽  
Peter von Dadelszen ◽  
...  
Keyword(s):  
Randomized Trial ◽  
Antihypertensive Treatment ◽  
Severe Hypertension ◽  
Hypertension In Pregnancy ◽  
In Pregnancy

scholarly journals Hypertension in pregnancy in general practice

2019 ◽  
Vol 23 (2) ◽  
pp. 15-20
Author(s):  
Irina Е. Moiseeva
Keyword(s):  
Pregnant Women ◽  
Negative Impact ◽  
Gestational Hypertension ◽  
Chronic Hypertension ◽  
Proper Treatment ◽  
Social Significance ◽  
Knowledge And Skills ◽  
Hypertension In Pregnancy ◽  
Treatment And Prevention ◽  
In Pregnancy

Hypertension occurs in 5–30% of pregnant women. Its medical and social significance is associated with the risk of a negative impact on the course of pregnancy and on the condition of the fetus and newborn.This requires from the general practitioner to have enough knowledge and skills in this area.Clinical variants of hypertension in pregnancy include pre-existing hypertension (chronic hypertension), gestational hypertension, chronic hypertension complicated by preeclampsia, and preeclampsia/eclampsia.The main tasks of general practitioners — early diagnosis, proper treatment and prevention of complications of hypertension in pregnant women.

Depression, Antidepressants and Hypertensive Disorders of Pregnancy: A Systematic Review

2019 ◽  
Vol 14 (2) ◽  
pp. 102-108 ◽  
Author(s):  
Sabrina Youash ◽  
Verinder Sharma
Keyword(s):  
Systematic Review ◽  
Systematic Reviews ◽  
Gestational Hypertension ◽  
Research Question ◽  
Current Evidence ◽  
Hypertensive Disorders Of Pregnancy ◽  
Hypertension In Pregnancy ◽  
Hypertensive Disorders ◽  
The Relationship ◽  
In Pregnancy

Background: Hypertensive disorders of pregnancy including gestational hypertension, preeclampsia and eclampsia are conditions that cause significant perinatal and maternal morbidity and mortality. </P><P> Objective: This is a systematic review of the current evidence examining the relationship between both depression and antidepressants on pregnancy-related hypertensive conditions. </P><P> Methods: In accordance with the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) protocol, six databases were searched for articles published between January 1990 and December 2017 (PubMed, Embase, PsycINFO, Cochrane Database of Systematic Reviews, MEDLINE and ClinicalTrials. gov). Randomized control trials, cohort studies and case-control studies were included in this review. Studies that measured the following exposures were included: Antidepressant exposure or diagnosis of depression. Studies that measured the following outcomes were included: Gestational hypertension, preeclampsia or eclampsia. A combination of keywords, as well as Medical Subject Headings (MeSH) index terms, was used for three general categories: antidepressants, depression and hypertensive disorders of pregnancy. A total of 743 studies were identified and 711 were excluded based on relevance to the research question. Twenty studies were included in the final systematic review. </P><P> Results: Of the twenty relevant studies, ten specifically examined the relationship between depression and hypertension in pregnancy. Only two of these did not find a significant association. Of the ten studies that concentrated on antidepressant medications, all except one found an association with hypertension in pregnancy to varying degrees. </P><P> Conclusion: Review of the literature suggests a possible association between depression and antihypertensive medications with pregnancy-related hypertension, but further studies are needed.</P>

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