Evaluation of creatine kinase level during long-term tocolysis

2002 ◽  
Vol 30 (6) ◽  
Author(s):  
Y. Matsuda ◽  
Y. Nagayoshi ◽  
N. Kirihara
Keyword(s):  
Creatine Kinase ◽  
Creatine Kinase Level

scholarly journals Hydroxychloroquine-Induced Creatine Kinase Elevation

2020 ◽  
Vol 25 (4) ◽  
pp. 599-602
Author(s):  
Sinem Bayrakçı ◽  
Nursel Sürmelioğlu ◽  
Ezgi Özyılmaz
Keyword(s):  
Risk Factors ◽  
Intensive Care Unit ◽  
Creatine Kinase ◽  
Intensive Care ◽  
General Condition ◽  
Creatine Kinase Level ◽  
Loading Dose ◽  
Term Administration ◽  
Drug Cessation

Long-term administration of hydroxychloroquine and chloroquine leads to deposition in the tissues including muscles, nerves and retina. Here, we report a case of hydroxychloroquine induced creatine kinase elevation after loading dose. An 80-year-old man with comorbidities, presented with a dry cough, high fever, diarrhea and general condition disorder ongoing for the last 3 days. The patient was admitted to the intensive care unit. The treatment was commenced with hydroxychloroquine. On the first day of treatment, the loading dose of hydroxychloroquine was started as 400 mg q12h, and treatment was continued as 200 mg q12h from the 3rd dose. After the hydroxychloroquine loading dose, the patient’s creatine kinase level increased, and after drug cessation, the level decreased. Hydroxychloroquine-induced creatine kinase elevated may be on not only long-term use but also acute period. Clinicians should have a high suspicion for hydroxychloroquine toxicity in patients with risk factors.

Elevated Serum Creatine Kinase Level in Rotavirus Gastroenteritis

2005 ◽  
Vol 8 (2) ◽  
pp. 117 ◽  
Author(s):  
Won Tae Bae ◽  
Jae Hui Kim ◽  
Eun Sil Park ◽  
Ji Hyun Seo ◽  
Jae Young Lim ◽  
...  
Keyword(s):  
Creatine Kinase ◽  
Creatine Kinase Level ◽  
Elevated Serum ◽  
Serum Creatine Kinase ◽  
Rotavirus Gastroenteritis ◽  
Serum Creatine Kinase Level

Troponin T is a better predictor than creatine kinase-MB of long-term mortality after coronary artery bypass graft surgery

2012 ◽  
Vol 164 (5) ◽  
pp. 779-785 ◽  
Author(s):  
Camilla Lund Søraas ◽  
Charlotte Friis ◽  
Kristin Victoria Tunheim Engebretsen ◽  
Leiv Sandvik ◽  
Sverre Erik Kjeldsen ◽  
...  
Keyword(s):  
Creatine Kinase ◽  
Coronary Artery ◽  
Coronary Artery Bypass Graft ◽  
Troponin T ◽  
Artery Bypass ◽  
Bypass Graft ◽  
Artery Bypass Graft ◽  
Creatine Kinase Mb ◽  
Long Term Mortality

scholarly journals Seven-Digit Creatine Kinase in Acute Rhabdomyolysis in a Child

2017 ◽  
Vol 4 ◽  
pp. 2329048X1668439 ◽  
Author(s):  
Nuha Basheer ◽  
Sirin Mneimneh ◽  
Mariam Rajab
Keyword(s):  
Renal Failure ◽  
Creatine Kinase ◽  
Acute Renal Failure ◽  
Creatine Kinase Level ◽  
Peak Plasma ◽  
Renal Dialysis ◽  
Acute Rhabdomyolysis ◽  
Threatening Condition ◽  
Life Threatening ◽  
Plasma Creatine Kinase

Rhabdomyolysis is an acute life-threatening condition that can occur in childhood secondary to many causes. The authors report the case of a 3-year-old male child who presented with acute rhabdomyolysis. The peak plasma creatine kinase level was extremely high. The 2 main causes of rhabdomyolysis in childhood are viral myositis and trauma, which can sometimes lead to acute renal failure. The highest creatine kinase levels reported in the literature so far was a 6-digit level in 2014 case report. In this study, the authors report the case of a 7-digit creatine kinase level in a child secondary to viral myositis who did not require renal dialysis.

Infantile polymyositis with normal serum creatine kinase level

1997 ◽  
Vol 19 (1) ◽  
pp. 63-65 ◽  
Author(s):  
Sarenur Tütüncüogˇlu ◽  
Hasan Tekgül ◽  
Eren Demirtas¸ ◽  
Seval Uysal
Keyword(s):  
Creatine Kinase ◽  
Creatine Kinase Level ◽  
Normal Serum ◽  
Serum Creatine Kinase ◽  
Serum Creatine Kinase Level

scholarly journals CREATININE AND CREATINE KINASE RATIO IN BLOOD OF DIFFERENT BODY TYPES - A NEW APPROACH.

2021 ◽  
Vol 4 (2) ◽  
Author(s):  
Anupam Bandyopadhyay ◽  
Pritha Chatterjee
Keyword(s):  
Creatine Kinase ◽  
Creatinine Level ◽  
Creatine Kinase Level ◽  
Fat Content ◽  
Standard Laboratory ◽  
Laboratory Methods ◽  
New Approach ◽  
Modifiable Factors ◽  
Post Hoc ◽  
One Way Anova

Purpose: The inconsistencies and variations of creatine kinase level due to modifiable and non-modifiable factors were the basis of this study. The aim was to find out the relationships between creatinine and creatine kinase in the blood of somatotypes.    Methods: The 122 males, aged 10 to 20 years, were classified according to their somatotypes. Somatotypes were measured by the ISAK method. By standard laboratory methods, creatinine and creatine kinase estimate. The IBM SPSS version 24 is used for calculation. One way ANOVA followed by post hoc tests was performed to compare the variables among the three groups (p<0.05).   Results: Creatinine level in the blood insignificantly deferred among the three somatotypes. The significant differences (p<0.05) were found in creatine kinase level in the blood and creatinine/creatine kinase ratio among the three dominant Somatotypes. Creatine Kinase was significantly higher in Ectomorphs (212 U/L) than Endomorphs. Ectomorphs and mesomorphs have crossed normal creatine kinase levels (35 -175 U/L). The creatinine/creatine kinase ratio was found highest in endomorphs and lowest in the ectomorphs and significantly differed in three Somatotypes.   Conclusion: Creatinine production remains the same, indicating production of Creatinine is independent of specific body types. A significant higher Creatine Kinase level in Ectomorphs over Endomorphs showed fat content was not associated with it. Significant differences in Creatinine / Creatine Kinase ratio among Somatotypes suggested its relevance between cellular and morphological relationships and might uses as biomarkers. 

scholarly journals Effects of Long-term Nonylphenol Exposure on Myocardial Fibrosis and Cardiac Function in Rats

2021 ◽  
Author(s):  
Chao Liu ◽  
Chengyu Ni ◽  
Weichu Liu ◽  
Xiaolian Yang ◽  
Renyi Zhang ◽  
...  
Keyword(s):  
Creatine Kinase ◽  
Myocardial Fibrosis ◽  
Posterior Wall ◽  
Anterior Wall ◽  
Left Ventricular ◽  
Environmental Estrogens ◽  
Control Group ◽  
Cardiac Structure ◽  
Collagen Iii

Abstract Background: Myocardial fibrosis is a critical pathological basis for the poor prognosis of cardiovascular diseases. Studies have found that myocardial fibrosis is closely associated with exposure to environmental estrogens such as nonylphenol (NP), as a representative of environmental estrogens. The aim of this study was to examine the effects of NP chronic exposure on myocardial fibrosis as well as cardiac structure and function. Forty Sprague Dawley rats were randomly divided into four groups (n = 10): control group (C), low NP dose (0.4 mg/kg, L), medium NP dose (4 mg/kg, M), and high NP dose (40 mg/kg, H) groups. The NP dose groups were gavaged with NP for 180 days. Results: The NP level in the heart of the NP groups was significantly higher than those in the control group (F = 43.658, P < 0.001). Serum aspartate aminotransferase (AST), creatine kinase (CK), creatine kinase isozyme (CK-MB), lactate dehydrogenase (LDH) and α-hydroxybutyrate dehydrogenase (α-HBDH) significantly increased in the NP groups compared with the control group (). Histopathological examination of the heart biopsy illustrates that in the medium and high NP groups, the fibrous connective tissue had a disordered and loose gridding shape, muscle fibers had fractured, and muscle fibers were loose with a widened gap. Extensive inflammatory cell infiltration and fibroblast proliferation in the myocardial interstitium were also found. With increasing NP dose, the degree of muscle fiber loosing and disorder became more significant in the NP treatment groups, and the collagen volume fraction (CVF) was higher than that in the control group (P < 0.01). Compared with the control group, the expression of collagen I and collagen III increased significantly in the medium and high NP groups (P < 0.05). The values of the systolic thickness of the left ventricular anterior wall (LVAWs), the diastolic thickness of the left ventricular posterior wall (LVPWd), the systolic thickness of the left ventricular posterior wall (LVPWs), and the left ventricular anterior wall (LVAWd) in the NP groups are were slightly lower than those in of the control group. The values of left ventricular end systolic dimensions (LVIDs) in the NP groups increased compared with the control group. Conclusions: Long-term NP exposure could lead to fibrosis in the rat myocardium, which is characterized by increased expressions of myocardial collagen I and collagen III, as well as elevated cardiac enzymes. In addition, the cardiac structure was affected and changes were observed in the thinner ventricular wall and as an enlarged ventricular cavity.

Postictal Elevation of Serum Creatine Kinase Level

1983 ◽  
Vol 40 (5) ◽  
pp. 315-317 ◽  
Author(s):  
A. L. Chesson ◽  
E. J. Kasarskis ◽  
V. W. Small
Keyword(s):  
Creatine Kinase ◽  
Creatine Kinase Level ◽  
Serum Creatine Kinase ◽  
Serum Creatine Kinase Level
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