Clinical characteristics at presentation of type 1 diabetes mellitus in children younger than 15 years in Croatia

2011 ◽  
Vol 24 (9-10) ◽  
Author(s):  
Gordana Stipancic ◽  
Marija Pozgaj Sepec ◽  
Lavinija La Grasta Sabolic ◽  
Ana Radica ◽  
Veselin Skrabic ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Type 1 Diabetes ◽  
Type 1 Diabetes Mellitus ◽  
Clinical Characteristics

The prevalence, immune profile, and clinical characteristics of children with celiac disease and type 1 diabetes mellitus in the state of Qatar

2021 ◽  
Vol 0 (0) ◽  
Author(s):  
Basma Haris ◽  
Ahmed Abdellatief ◽  
Houda Afyouni ◽  
Tasneem Abdel-Karim ◽  
Shayma Mohammed ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Type 1 Diabetes ◽  
Celiac Disease ◽  
Type 1 Diabetes Mellitus ◽  
Clinical Characteristics ◽  
Family History Of Diabetes ◽  
Positive Type ◽  
Immune Profile ◽  
Insulin Autoantibody

Abstract Objectives Children with antibody positive type 1 diabetes mellitus (type 1 diabetes) are at an increased risk of developing celiac disease (CD) which suggests a common autoimmune basis with both high-risk human lymphocyte antigen (HLA) and non-HLA factors playing a role in the pathophysiology. We aim to describe the prevalence, immune profile, and clinical characteristics of children with CD who have type 1 diabetes mellitus in Qatar. Methods All children (aged 0–18 years) attending a regional diabetes clinic with antibody positive type 1 diabetes were screened for CD. Measurement of tissue transglutaminase IgA and IgG as well as anti-endomysial antibody, was done, clinical details about the birth history, family history of diabetes and CD, age of onset, and ethnicity were collected. Results Out of the 1,325 children with antibody positive type 1 diabetes, 54 were identified to have CD on screening and then confirmed on small bowel biopsy. The prevalence of CD in the type 1 diabetes childhood population in Qatar is 4.07%. CD and type 1 diabetes were more prevalent in the Qatari children (n=32) as compared to non-Qatari (n=22) and occurred mostly in the age group 6–10 years. The most common type 1 diabetes antibodies in children with CD were glutamic acid decarboxylase and insulin autoantibody. Twelve subjects were asymptomatic for CD symptoms and picked up only on screening. Conclusions The prevalence of CD in children with type 1 diabetes in Qatar is comparable to reports from around the world. Many children were asymptomatic and thus routine screening is recommended.

Abstract #1038612: Transition from Pediatric to Adult Care in Type 1 Diabetes Mellitus: A Llongitudinal Analysis of Clinical Characteristics and Outcomes

2021 ◽  
Vol 27 (6) ◽  
pp. S70-S71
Author(s):  
Diana Soliman ◽  
Alison Manning ◽  
Gary Maslow ◽  
Karen Chiswell ◽  
Aruna Rikhi ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Type 1 Diabetes ◽  
Type 1 Diabetes Mellitus ◽  
Clinical Characteristics ◽  
Adult Care

scholarly journals Estimated glucose disposal rate demographics and clinical characteristics of young adults with type 1 diabetes mellitus: A cross-sectional pilot study

2020 ◽  
Vol 17 (5) ◽  
pp. 147916412095232
Author(s):  
Revathi Nishtala ◽  
Noppadol Kietsiriroje ◽  
Mohammad Karam ◽  
Ramzi A Ajjan ◽  
Sam Pearson
Keyword(s):  
Diabetes Mellitus ◽  
Type 1 Diabetes ◽  
Type 1 Diabetes Mellitus ◽  
Clinical Characteristics ◽  
Glucose Disposal ◽  
Cross Sectional ◽  
Lipid Management ◽  
Estimated Glucose Disposal Rate ◽  
Glucose Disposal Rate

Background: Estimated glucose disposal rate (eGDR) is a practical measure of Insulin Resistance (IR) which can be easily incorporated into clinical practice. We profiled eGDR in younger adults with type 1 diabetes mellitus (T1DM) by their demographic and clinical characteristics. Methods: In this single centre study, medical records of TIDM were assessed and eGDR tertiles correlated with demographic and clinical variables. Results: Of 175 T1DM individuals, 108 (61.7%) were males. Mean age (±SD) was 22.0 ± 1.6 years and median time from diagnosis 11.0 years (range 1–23). Individuals were predominantly Caucasian (81.7%), with 27.4% being overweight (BMI: 25–30 kg/m2) and 13.7% obese (BMI > 30 kg/m2). Mean total cholesterol (TC) levels were significantly lower in high and middle eGDR tertiles (4.4 ± 1 and 4.3 ± 0.8 mmol/l, respectively) compared with low eGDR tertile (4.8 ± 1, p < 0.05 for both). Triglyceride (TG) levels showed a similar trend at 1.1 ± 0.5 and 1.1 ± 0.5 mmol/l for high and middle eGDR tertile compared to low eGDR tertile (1.5 ± 1 mmol/l, p < 0.05 for both). Renal function was similar across eGDR tertiles and no difference in retinopathy was detected. Conclusion: TC and TG are altered in individuals with T1DM and low eGDR, suggesting that this subgroup requires optimal lipid management to ameliorate their vascular risk.

Clinical Characteristics of 261 Cases of Hospitalized Patients with Type 1 Diabetes Mellitus

2016 ◽  
Vol 31 (2) ◽  
pp. 69-75
Author(s):  
Jing Yang ◽  
Mei-cen Zhou ◽  
Kai Feng ◽  
Ou Wang ◽  
Hua-bing Zhang ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Type 1 Diabetes ◽  
Type 1 Diabetes Mellitus ◽  
Clinical Characteristics ◽  
Hospitalized Patients

Expression of miR-22 and miR-150 in type 1 diabetes mellitus: Possible relationship with autoimmunity and clinical characteristics

2016 ◽  
Vol 147 (6) ◽  
pp. 245-247 ◽  
Author(s):  
Santiago Estrella ◽  
Diego F. Garcia-Diaz ◽  
Ethel Codner ◽  
Patricia Camacho-Guillén ◽  
Francisco Pérez-Bravo
Keyword(s):  
Diabetes Mellitus ◽  
Type 1 Diabetes ◽  
Type 1 Diabetes Mellitus ◽  
Clinical Characteristics
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