Bone Maturation in 1788 Children and Adolescents with Diabetes Mellitus Type 1

2010 ◽  
Vol 23 (9) ◽  
Author(s):  
Axel Dost ◽  
Tilman Rohrer ◽  
Jörg Fussenegger ◽  
Christian Vogel ◽  
Bernd Schenk ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Children And Adolescents ◽  
Diabetes Mellitus Type 1 ◽  
Diabetes Mellitus Type ◽  
Bone Maturation

Association between IgE-mediated allergies and diabetes mellitus type 1 in children and adolescents

2015 ◽  
Vol 16 (7) ◽  
pp. 493-503 ◽  
Author(s):  
Sabine Klamt ◽  
Mandy Vogel ◽  
Thomas M Kapellen ◽  
Andreas Hiemisch ◽  
Freerk Prenzel ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Children And Adolescents ◽  
Diabetes Mellitus Type 1 ◽  
Diabetes Mellitus Type ◽  
Ige Mediated

scholarly journals Difficulties concerning Diabetes Mellitus Type 1 in children and adolescents

Rev Rene ◽  
2016 ◽  
Vol 17 (5) ◽  
pp. 651 ◽  
Author(s):  
Tatiana Rebouças Moreira ◽  
Samila Torquato Araújo Bandeira ◽  
Synara Cavalcante Lopes ◽  
Silvana Linhares de Carvalho ◽  
Francisca Diana Da Silva Negreiros ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Children And Adolescents ◽  
Diabetes Mellitus Type 1 ◽  
Diabetes Mellitus Type

scholarly journals Characteristics of insulin therapy of diabetes mellitus type 1 in children and adolescents receiving glucocorticoids

2019 ◽  
Vol 22 (3) ◽  
pp. 263-273
Author(s):  
Alisa V. Vitebskaya ◽  
Anastaiya V. Popovich ◽  
Elena Y. Afonina ◽  
Yuliya O. Kostina ◽  
Karina V. Aleksanyan ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Glycemic Control ◽  
Insulin Therapy ◽  
Children And Adolescents ◽  
Diabetes Mellitus Type 1 ◽  
Diabetes Mellitus Type ◽  
Insulin Requirements ◽  
Acting Insulin ◽  
High Doses

BACKGROUND: In coexistence of diabetes mellitus type 1 (DM1) with severe autoimmune and inflammatory diseases some patients need simultaneous administration of insulin and glucocorticoids (GC). GC therapy in patients with DM1 can worsen glycemic control. AIM: To determine characteristics of insulin therapy of DM1 in children and adolescents receiving GC. DESCRIPTION OF CLINICAL CASES: We observed 5 patients with DM1 receiving GC for juvenile idiopathic arthritis (JIA), juvenile systemic sclerosis (JSS), juvenile dermatomyositis (JDM), ulcerative colitis (UC), and reactive arthritis (RA). Intra-articular administration of GC did not significantly influence glycemic control. In case of GC pulse therapy hyperglycemia and increased insulin requirements were recognized in 36 hours after GC receipt, persisted from few hours up to 3 days after each administration. While therapy with oral GC in high doses the worst glycemic control was registered in daylight hours. To overcome insulin resistance change of time of injection and 10%-increase of long-acting insulin analogue, additional injections of ultrashort-acting insulin analogues, temporal prescription of short-acting human insulin were used. While GC therapy insulin daily dose was individual and could reach 2.0 U/kg. After transition to maintaining doses of GC or discontinuation of GC therapy patients returned to standard or relatively low insulin requirements. Levels of glycosylated hemoglobin differed significantly among patients at different stages of treatment, were maximal while long-term therapy with high doses of oral GC, but mostly depended on patients compliance. CONCLUSION: Bettering of glycemic control while receiving GC can be reached by timely dose correction of insulin therapy, selection of individual schemes, taking into account time of receipt and pharmacokinetic characteristics of GC. Adherence of the patient and his family to treatment of DM1 plays an important role in glycemic control.

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