scholarly journals Multi–Frequency Analysis For Interstitial Microwave Hyperthermia Using Multi–Slot Coaxial Antenna

2015 ◽  
Vol 66 (1) ◽  
pp. 26-33 ◽  
Author(s):  
Piotr Gas
Keyword(s):  
Thermal Therapy ◽  
Microwave Antenna ◽  
Human Tissues ◽  
The Finite Element Method ◽  
Bioheat Equation ◽  
Slot Antennas ◽  
Hyperthermia Treatment ◽  
Microwave Frequencies ◽  
Symmetrical Model ◽  
Microwave Hyperthermia

Abstract The presented paper shows a new concept of multi-slot coaxial antenna working at different frequencies to predict the best solution for interstitial microwave hyperthermia treatment. The described method concerns a microwave heating of unhealthy cells using a thin microwave antenna located in the human tissue. Therefore, the coupled wave equation in a sinusoidal steady-state and the transient bioheat equation under an axial symmetrical model are considered. The 4-Cole-Cole approximation has been used to compute the complex relative permittivity of the human tissues at different antenna operating frequencies. At the stage of numerical simulation the finite element method (FEM) is used. Special attention has been paid to estimate the optimal antenna parameters for thermal therapy for three microwave frequencies mainly used in medical practice and make comparison of the obtained results in the case of single-, double- and triple-slot antennas.

scholarly journals Microwave hyperthermia treatment increases heat shock proteins in human skeletal muscle * COMMENTARY

2007 ◽  
Vol 41 (7) ◽  
pp. 453-455 ◽  
Author(s):  
Y. Ogura ◽  
H. Naito ◽  
T. Tsurukawa ◽  
N. Ichinoseki-Sekine ◽  
N. Saga ◽  
...  
Keyword(s):  
Skeletal Muscle ◽  
Heat Shock ◽  
Heat Shock Proteins ◽  
Human Skeletal Muscle ◽  
Hyperthermia Treatment ◽  
Shock Proteins ◽  
Microwave Hyperthermia

Time Dependent Mathematical Model of Thermoregulation in Human Dermal Parts During Sarcopenia

2021 ◽  
Vol 4 (1) ◽  
pp. 41-53
Author(s):  
Dev Chandra Shrestha ◽  
Saraswati Acharya
Keyword(s):  
Body Weight ◽  
Muscle Mass ◽  
Vital Role ◽  
Time Dependent ◽  
The Finite Element Method ◽  
Bioheat Equation ◽  
One Dimensional ◽  
Metabolic Heat ◽  
Human Body Temperature ◽  
Weight Impact

Sarcopenia is an illness characterized by the loss of skeletal muscle mass, and its strength occurs in aging after 50 years. Muscle mass plays a vital role in body weight and metabolism. The loses in body weight impact reducing the basal metabolic rate (BMR). The BMR affects the human body temperature due to lower metabolic heat production during sarcopenia. The present study deals with time dependent temperature variation in human dermal parts during sarcopenia. The finite element method is used to solve a one-dimensional bioheat equation. In this model, the thickness of the epidermis, dermis layers, and the BMR of different aging, are estimated. The results show the nodal temperature of the epidermis and dermis layers increases due to reducing the thickness. Further, the subcutaneous nodal temperature slightly decreases due to the cause of BMR.

Heating characteristics of coaxial-slot antennas for minimally invasive microwave thermal therapy

1999 ◽  
Author(s):  
Koichi Ito ◽  
Hiroyuki Yoshimura ◽  
Kazuyuki Saito ◽  
Lira Hamada
Keyword(s):  
Minimally Invasive ◽  
Thermal Therapy ◽  
Slot Antennas

The Effects of Large Blood Vessels on Three-Dimensional Tissue Temperature Distributions During Electromagnetic Induced Nano-Hyperthermia: Numerical Simulation

2008 ◽  
Author(s):  
Zhong-Shan Deng ◽  
Jing Liu
Keyword(s):  
Blood Vessels ◽  
Tumor Cells ◽  
Three Dimensional ◽  
The Body ◽  
Thermal Therapy ◽  
Tissue Temperature ◽  
Surrounding Tissue ◽  
Temperature Profiles ◽  
Hyperthermia Treatment ◽  
Tumor Hyperthermia

As is well known, the blood flowing through large blood vessels acts as a heat sink and plays an important role in affecting temperature profiles of heated tissues [1]. In hyperthermia, heating is usually limited to the tumor and a small margin of the surrounding tissue. Since the temperatures in the rest of the body remain normal, the blood that supplies the tumor will be relatively cold. Consequently, the blood flow inside a large vessel will represent a sink which cools the nearby heated tissues and then limits heating lesion during tumor hyperthermia. Under this adverse condition, a part of vital tumor cells may remain in the thermally lethal area and lead to recurrence of tumors after hyperthermia treatment. More specifically, tumor cell survival in the vicinity of large blood vessels is often correlated with tumor recurrence after thermal therapy. Therefore, it is difficult to implement an effective hyperthermia treatment when a tumor is contiguous to a large blood vessel or such vessel transits the tumor. How to totally destroy tumor cells in the vicinity of large blood vessels has been a major challenge in hyperthermia [2].

scholarly journals Optimal Control of Thermal Damage to Targetted Regions in a Biological Material

Volume 4 ◽  
2004 ◽  
Author(s):  
F. Scott Gayzik ◽  
Elaine P. Scott ◽  
Tahar Loulou
Keyword(s):  
Objective Function ◽  
Thermal Damage ◽  
Numerical Technique ◽  
Damage Model ◽  
Gradient Algorithm ◽  
Bioheat Equation ◽  
Hyperthermia Treatment ◽  
Potential Applications ◽  
Damage Field ◽  
The Relationship

A numerical technique with potential applications in hyperthermia treatment planning is presented. The treatment is simulated using a 2D transient computational model of the Pennes bioheat equation within an optimization algorithm. The algorithm recovers the heating protocol which will lead to a desired damage field. The relationship between temperature, time and thermal damage is expressed as a first order rate process using the Arrhenius equation. The objective function of the control problem is based on this thermal damage model. The adjoint method in conjunction with the conjugate gradient algorithm is used to minimize the objective function. The results from a numerical simulation show good agreement between the optimal damage field and the damage field recovered by the algorithm. A comparison between the recovered damage field and the commonly used thermal dose is also made.

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