Degradation of chitosan in the presence of poly(vinyl alcohol) and poly(acrylic acid) by a crude enzyme complex from Trichoderma viride

e-Polymers ◽  
2003 ◽  
Vol 3 (1) ◽  
Author(s):  
Dilyana Paneva ◽  
Rosica Mincheva ◽  
Olya Stoilova ◽  
Nevena Manolova ◽  
Iliya Rashkov
Keyword(s):  
Acrylic Acid ◽  
Vinyl Alcohol ◽  
Biocontrol Agent ◽  
Trichoderma Viride ◽  
Crude Enzyme ◽  
Poly Vinyl Alcohol ◽  
Enzyme Complex ◽  
Optimal Conditions ◽  
Experimental Conditions ◽  
Poly Acrylic Acid

Abstract The degradation of chitosan in the presence of poly(vinyl alcohol) (PVA) or poly(acrylic acid) (PAA) by a crude enzyme complex from Trichoderma viride was studied. It was found that neither PVA nor PAA suppress chitosan hydrolysis. By varying the experimental conditions, the optimal conditions for chitosan degradation in the presence of PVA (37°C, pH 6) or PAA (37°C, pH 4) were found. The biocontrol agent T. viride was embedded in films of chitosan, PVA, chitosan/PVA and chitosan/PAA. Microbiological tests showed that T. viride retained its ability to develop and reproduce in all studied film types. The obtained results imply that the prepared systems are appropriate carriers of biocontrol agents and might be used as novel agropharmaceuticals.

Evaluation of Thermally Crosslinked Poly(Acrylic Acid-Co-Maleic Acid) (PAMA)/Poly(Vinyl Alcohol) (PVA) Microneedle Arrays

2019 ◽  
Vol 819 ◽  
pp. 45-50 ◽  
Author(s):  
Nway Nway Aung ◽  
Yin Yin Myat ◽  
Tanasait Ngawhirunpat ◽  
Theerasak Rojanarata ◽  
Prasopchai Patrojanasophon ◽  
...  
Keyword(s):  
Acrylic Acid ◽  
Maleic Acid ◽  
Vinyl Alcohol ◽  
Transdermal Drug Delivery ◽  
Poly Vinyl Alcohol ◽  
Optimal Conditions ◽  
Microneedle Arrays ◽  
First Time ◽  
Polymer Ratio ◽  
Poly Acrylic Acid

This study aimed to evaluate the optimal conditions for crosslinked of PAMA/PVA microneedle (MN) arrays. Poly (acrylic acid-co-maleic acid) (PAMA)/poly (vinyl alcohol) (PVA) MN arrays were fabricated for the first time using the micromolding technique. The PAMA/PVA MN arrays at the polymer ratio of 1:4 were sharp, homogenous and perfectly formed with an elegant appearance. The successfully crosslinking MN arrays were determined using FTIR and water insolubilization. The results showed that increasing the crosslinking temperature and time, the degree of crosslinking also improved, which results in a decline in water uptake. The optimal crosslinking condition for PAMA/PVA MN arrays was 130°C for 1 h. Moreover, the highest swelling was observed from crosslinked PAMA/PVA MN arrays at 90°C for 0.5 h. These studies suggest that the combination of PAMA and PVA for fabrication of MN arrays could have a great potential to develop both hydrogel and dissolving MN devices for transdermal drug delivery.

Synthesis, characterization, and their some chemical and biological properties of PVA/PAA/nPS hydrogel nanocomposites: Hydrogel and wound dressing

2020 ◽  
Vol 35 (3) ◽  
pp. 203-215
Author(s):  
Mehmet Emin Diken ◽  
Berna Koçer Kizilduman ◽  
Begümhan Yilmaz Kardaş ◽  
Enes Emre Doğan ◽  
Mehmet Doğan ◽  
...  
Keyword(s):  
Fourier Transform ◽  
Acrylic Acid ◽  
Infrared Spectra ◽  
Vinyl Alcohol ◽  
Fourier Transform Infrared ◽  
Poly Vinyl Alcohol ◽  
Seed Particles ◽  
Fourier Transform Infrared Spectra ◽  
Hydrogel Nanocomposites ◽  
Poly Acrylic Acid

The nanocomposite hydrogels were prepared by dispersing of the nanopomegranate seed particles into poly(vinyl alcohol)/poly(acrylic acid) blend matrix in an aqueous medium by the solvent casting method. These hydrogels were characterized using scanning electron microscopy, Fourier transform infrared spectra, differential scanning calorimetry, and optical contact angle instruments. The nanopomegranate seed, blend, and hydrogel nanocomposites were tested for microbial activity. In addition, cytocompatibilities of these blend and hydrogel nanocomposites/composites were tested on human lymphocyte with in vitro MTS cell viability assays. Fourier transform infrared spectra revealed that esterification reaction took place among functional groups in the structure of poly(vinyl alcohol) and poly(acrylic acid). The hydrophilic properties of all hydrogels decreased with increasing nanopomegranate seed content. The mean diameters of the nanopomegranate seed particles were about 88 nm. Nanopomegranate seed particles demonstrated antibacterial properties against gram-positive bacteria, Staphylococcus aureus, and gram-negative bacteria, Escherichia coli. The lymphocyte viabilities increased after addition of nanopomegranate seeds into the polymer blend. The swelling behavior of blend and hydrogels was dependent on the cross-linking density created by the reaction between poly(vinyl alcohol)/poly(acrylic acid) blend and nanopomegranate seed. Scanning electron microscopy images were highly consistent with Fourier transform infrared spectra, differential scanning calorimetry, and antibacterial activity results.

Poly(acrylic acid)-block-poly(vinyl alcohol) anchored maghemite nanoparticles designed for multi-stimuli triggered drug release

Nanoscale ◽  
2013 ◽  
Vol 5 (23) ◽  
pp. 11464 ◽  
Author(s):  
Ji Liu ◽  
Christophe Detrembleur ◽  
Antoine Debuigne ◽  
Marie-Claire De Pauw-Gillet ◽  
Stéphane Mornet ◽  
...  
Keyword(s):  
Drug Release ◽  
Acrylic Acid ◽  
Vinyl Alcohol ◽  
Poly Vinyl Alcohol ◽  
Maghemite Nanoparticles ◽  
Triggered Drug Release ◽  
Poly Acrylic Acid
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